公开(公告)号：US20180037871A1

公开(公告)日：2018-02-08

申请号：US15230634

申请日：2016-08-08

申请人： Thai-Yen Ling

发明人： Thai-Yen Ling ,  Sui-Yuan Chang ,  Tai-Ling Chao ,  Sing-Yi Gu ,  Yufeng Jane Tseng ,  Ming-Tsung Hsu

IPC分类号： C12N7/00 ,  C07K14/47 ,  C12N15/85

CPC分类号： C12N7/00 ,  C07K14/47 ,  C12N5/0693 ,  C12N15/85 ,  C12N15/86 ,  C12N2501/603 ,  C12N2510/00 ,  C12N2710/10022 ,  C12N2740/10043 ,  C12N2770/32322

摘要： The present invention relates to a cancer initiating cell comprising an isolated coxsackievirus and adenovirus receptor positive mouse pulmonary stem/progenitor cell that overexpresses Oct-4.

公开(公告)号：US20070087332A1

公开(公告)日：2007-04-19

申请号：US11252458

申请日：2005-10-17

申请人： John Yu ,  Alice Yu ,  Thai-Yen Ling

发明人： John Yu ,  Alice Yu ,  Thai-Yen Ling

IPC分类号： C12Q1/70 ,  C12N7/00 ,  C12N5/08 ,  C12N15/86

CPC分类号： C12N7/00 ,  C12N5/0689 ,  C12N2500/25 ,  C12N2501/11 ,  C12N2760/16011 ,  C12N2770/20011

摘要： Isolated pulmonary stem cells, the isolated pulmonary stem cells being slowly dividing Oct-4 expressing cells forming individual colonies and able to undergoing terminal differentiation into a mature phenotype in vitro; a method to identify stem cells of a tissue; a kit for the identification of stem cell of a tissue; a method for identifying an infective agent able to infect pulmonary cells; a method for the production of a virus able to infect pulmonary cells and method for identifying a compound interfering with infection of a cell by an infective agent.

摘要翻译： 分离的肺干细胞，分离的肺干细胞正在缓慢分化形成单个菌落的Oct-4表达细胞，并能够在体外进行末端分化成成熟表型; 识别组织干细胞的方法; 用于鉴定组织干细胞的试剂盒; 用于鉴定能够感染肺细胞的感染剂的方法; 用于生产能够感染肺细胞的病毒的方法和用于鉴定通过感染剂干扰细胞感染的化合物的方法。