-
1.发明申请METHOD OF ANALYSING A BLOOD SAMPLE OF A SUBJECT FOR THE PRESENCE OF A FOETAL DISEASE OR CONDITION MARKER 审中-公开分析场症或病情标记存在的病人血液样本的方法公开(公告)号：US20140256590A1
公开(公告)日：2014-09-11
申请号：US14237424
申请日：2012-08-08
CPC分类号： C12Q1/6883 , C12Q1/6879 , C12Q2600/156 , C12Q2600/158 , G01N33/5023 , G01N33/689 , G01N33/86 , G01N2800/368 , G01N2800/385
摘要： The present invention relates to a method of analysing a blood sample of a subject carrying a foetus for the presence of a foetal disease or condition marker, said method comprising the steps of a) extracting nucleic acid from anucleated blood cells, preferably thrombocytes, in said blood sample to provide an anucleated blood cell-extracted nucleic acid fraction, and b) analysing said anucleated blood cell-extracted nucleic acid fraction for the presence of a foetal disease or condition marker, wherein said foetal disease or condition marker is a nucleic acid of a foetus, or wherein said foetal disease or condition marker is a foetal disease or condition-specific expression profile of genes of a cell of said foetus.
摘要翻译： 本发明涉及一种分析胎儿疾病或病症标记物携带胎儿的血液样本的方法，所述方法包括以下步骤：a）从所述胎儿疾病或病症标记中的未成熟血细胞，优选血小板提取核酸， 提供无核细胞提取的核酸级分的血液样品，以及b）分析所述无核细胞提取的核酸部分是否存在胎儿疾病或病症标记物，其中所述胎儿疾病或病症标记是 胎儿，或其中所述胎儿疾病或病症标记是所述胎儿的细胞的基因的胎儿疾病或条件特异性表达谱。
-
2.发明申请METHOD OF ANALYSING A BLOOD SAMPLE OF A SUBJECT FOR THE PRESENCE OF A DISEASE MARKER 审中-公开分析疾病标志物存在的病人血液样本的方法公开(公告)号：US20130196873A1
公开(公告)日：2013-08-01
申请号：US13809960
申请日：2011-07-15
IPC分类号： C12Q1/68
CPC分类号： C12Q1/6827 , C12Q1/6886 , C12Q2600/112 , C12Q2600/158
摘要： The present invention relates to a method of analyzing a blood sample of a subject for the presence of a disease marker, said method comprising the steps of a) extracting nucleic acid from anucleated blood cells in said blood sample to provide an anucleated blood cells-extracted nucleic acid fraction, and b) analysing said anucleated blood cells-extracted nucleic acid fraction for the presence of a disease marker, wherein said disease marker is a disease-specific mutation in a gene of a cell of said subject, or wherein said disease marker is a disease-specific expression profile of genes of a cell of said subject.
摘要翻译： 本发明涉及一种分析患者血液样本中疾病标志物存在的方法，所述方法包括以下步骤：a）从所述血液样品中的未核化血细胞提取核酸，以提供无核细胞提取的 核酸级分，以及b）分析所述无核细胞提取的核酸级分是否存在疾病标志物，其中所述疾病标志物是所述受试者的细胞基因中的疾病特异性突变，或其中所述疾病标记 是所述受试者的细胞的基因的疾病特异性表达谱。
-
公开(公告)号：US10174364B2
公开(公告)日：2019-01-08
申请号：US13809960
申请日：2011-07-15
IPC分类号： C12Q1/68 , C12Q1/6827 , C12Q1/6886
摘要： The present invention relates to a method of analyzing a blood sample of a subject for the presence of a disease marker, said method comprising the steps of a) extracting nucleic acid from anucleated blood cells in said blood sample to provide an anucleated blood cells-extracted nucleic acid fraction, and b) analyzing said anucleated blood cells-extracted nucleic acid fraction for the presence of a disease marker, wherein said disease marker is a disease-specific mutation in a gene of a cell of said subject, or wherein said disease marker is a disease-specific expression profile of genes of a cell of said subject.
-
-
搜索结果
3 条记录 (耗时 0.012 秒)
