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公开(公告)号：US5895654A
公开(公告)日：1999-04-20
申请号：US789727
申请日：1997-01-27
IPC: C12N1/20 , A61K20060101 , A61K9/14 , A61K9/19 , A61K35/74 , A61K39/02 , A61K39/05 , A61K39/08 , A61K39/085 , A61K39/09 , A61K39/12 , A61K39/145 , A61K39/193 , A61K39/245 , A61P11/00 , A61P31/04 , C12N20060101 , C12R1/46
CPC classification number: C12R1/46 , A61K39/092
Abstract: The present invention relates to a live attenuated strain of the bacterium Streptococcus equi, a pathogen causing strangles in horses. The invention also relates to a vaccine against strangles, methods for the preparation of such a vaccine and to the use of the strain for the preparation of such a vaccine.
Abstract translation: 本发明涉及一种细菌链球菌属的减毒菌株，其是在马中引起扼制的病原体。 本发明还涉及抗扼杀疫苗，制备这种疫苗的方法以及该菌株用于制备这种疫苗的用途。
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公开(公告)号：US06994855B1
公开(公告)日：2006-02-07
申请号：US09679643
申请日：2000-10-05
Applicant: Timothy James Foster , Damien Leo McDevitt
Inventor： Timothy James Foster , Damien Leo McDevitt
IPC: A61K39/40
CPC classification number: C07K16/1271 , C07K14/31 , C07K2317/76
Abstract: The invention relates to the isolation of the fibrinogen binding protein gene from Staphylococcus aureus and to the use of the fibrinogen binding protein and antibodies generated against it for wound healing, blocking adherence to indwelling medical devices, immunization or diagnosis of infection.
Abstract translation: 本发明涉及从金黄色葡萄球菌中分离纤维蛋白原结合蛋白基因，以及使用纤维蛋白原结合蛋白和针对其产生的针对伤口愈合的抗体，阻止对留置医疗器械的粘附，免疫或诊断感染。
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Patent Agency Ranking
公开(公告)号：US06177084B1
公开(公告)日：2001-01-23
申请号：US09421868
申请日：1999-10-19
Applicant: Timothy James Foster , Damien Leo McDevitt
Inventor： Timothy James Foster , Damien Leo McDevitt
IPC: A61K39085
CPC classification number: C07K14/31
Abstract: The isolation of the S. aureus fibrinogen binding protein gene is described and a minimal fibrinogen binding protein is identified. The protein finds use as a vaccine or a pharmaceutical composition for application to prevent infection, promotion of wound healing, blocking adherence to indwelling medical devices, or diagnosis of infection.
Abstract translation: 描述了金黄色葡萄球菌纤维蛋白原结合蛋白基因的分离，并鉴定了最小的纤维蛋白原结合蛋白。 该蛋白质可用作疫苗或药物组合物，用于预防感染，促进伤口愈合，阻止对留置医疗器械的依从性或感染诊断。
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公开(公告)号：US6008341A
公开(公告)日：1999-12-28
申请号：US293728
申请日：1994-08-22
Applicant: Timothy James Foster , Damien Leo McDevitt
Inventor： Timothy James Foster , Damien Leo McDevitt
CPC classification number: C07K14/31
Abstract: The isolation of the S. aureus fibrinogen binding protein gene is described and a minimal fibrinogen binding protein is identified. The protein finds use as a vaccine or a pharmaceutical composition for application to prevent infection, promotion of wound healing, blocking adherence to indwelling medical devices, or diagnosis of infection.
Abstract translation: 描述了金黄色葡萄球菌纤维蛋白原结合蛋白基因的分离，并鉴定了最小的纤维蛋白原结合蛋白。 该蛋白质可用作疫苗或药物组合物，用于预防感染，促进伤口愈合，阻止对留置医疗器械的依从性或感染诊断。
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公开(公告)号：US07838012B2
公开(公告)日：2010-11-23
申请号：US12115987
申请日：2008-05-06
Applicant: Timothy James Foster , Damien Leo McDevitt
Inventor： Timothy James Foster , Damien Leo McDevitt
IPC: A61K39/085
CPC classification number: C07K16/1271 , C07K14/31 , C07K2317/76
Abstract: The isolation of genes and proteins from Staphylococcus aureus is provided, and the nucleic acids coding for specific regions of the S. aureus protein are described. The nucleic acids encode proteins that can be useful as vaccines or in pharmaceutical compositions for application to prevent infection, promotion of wound healing, blocking adherence to indwelling medical devices, or diagnosis of infection.
Abstract translation: 提供了从金黄色葡萄球菌分离基因和蛋白质，并描述了编码金黄色葡萄球菌蛋白质的特定区域的核酸。 核酸编码可用作疫苗的蛋白质或用于预防感染，促进伤口愈合，阻止对留置医疗器械的依从性或诊断感染的药物组合物中的蛋白质。
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公开(公告)号：US20090246218A1
公开(公告)日：2009-10-01
申请号：US12115987
申请日：2008-05-06
Applicant: Timothy James FOSTER , Damien Leo McDevitt
Inventor： Timothy James FOSTER , Damien Leo McDevitt
IPC: A61K39/085
CPC classification number: C07K16/1271 , C07K14/31 , C07K2317/76
Abstract: The isolation of genes and proteins from Staphylococcus aureus is provided, and the nucleic acids coding for specific regions of the S. aureus protein are described. The nucleic acids encode proteins that can be useful as vaccines or in pharmaceutical compositions for application to prevent infection, promotion of wound healing, blocking adherence to indwelling medical devices, or diagnosis of infection.
Abstract translation: 提供了从金黄色葡萄球菌分离基因和蛋白质，并描述了编码金黄色葡萄球菌蛋白质的特定区域的核酸。 核酸编码可用作疫苗的蛋白质或用于预防感染，促进伤口愈合，阻止对留置医疗器械的依从性或诊断感染的药物组合物中的蛋白质。
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公开(公告)号：US07368112B2
公开(公告)日：2008-05-06
申请号：US11348437
申请日：2006-02-07
Applicant: Timothy James Foster , Damien Leo McDevitt
Inventor： Timothy James Foster , Damien Leo McDevitt
IPC: A61K39/40
CPC classification number: C07K16/1271 , C07K14/31 , C07K2317/76
Abstract: The isolation of genes and proteins from Staphylococcus aureus is provided, and the nucleic acids coding for specific regions of the S. aureus CIfA protein are described. The nucleic acids encode proteins that can be useful as vaccines or in pharmaceutical compositions for application to prevent infection, promotion of wound healing, blocking adherence to indwelling medical devices, or diagnosis of infection.
Abstract translation: 提供了从金黄色葡萄球菌分离基因和蛋白质，并描述了编码金黄色葡萄球菌CIfA蛋白质的特定区域的核酸。 核酸编码可用作疫苗的蛋白质或用于预防感染，促进伤口愈合，阻止对留置医疗器械的依从性或诊断感染的药物组合物中的蛋白质。
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