公开(公告)号：US20090098639A1

公开(公告)日：2009-04-16

申请号：US12162850

申请日：2007-01-31

Applicant: Oystein Ljungmann ,  Torstein Ljungmann

Inventor： Oystein Ljungmann ,  Torstein Ljungmann

IPC: G01N1/31

CPC classification number: G01N1/312 ,  G02B21/34 ,  G02B21/365 ,  Y10T436/2575

Abstract: An apparatus for automatic execution of different treatment operations in connection with staining of tissue specimens on microscope slides, wherein the apparatus (1) comprises a loading station (2) for microscope slides (7) with tissue specimens, a number of reagent stations (3) for staining of the tissue specimens on supplied microscope slides, a conveyor (5) for transfer of microscope slides (7) between the stations (3) in accordance with a staining program, an unloading station (10) for treated microscope slides, and a control unit (19) for controlling the treatment operations in accordance with a data program. The apparatus comprise a photo station (25) with a digital camera (26) for automatic photographing with a background light source of the finished treated tissue specimens on supplied microscope slides (7). The camera is connected to the control unit (19) of the apparatus and the control unit is arranged to store the picture of each individual tissue specimen and information which is located on the relevant microscopic slide (7) and preferably also information about the staining program and status of reagents at the reagent stations (3) for automatic transmission of the information to a place for result analysis.

Abstract translation: 一种用于自动执行与显微镜载片上的组织标本的染色相关的不同处理操作的装置，其中所述装置（1）包括用于具有组织标本的显微镜载片（7）的装载站（2），多个试剂站（3 ），用于在供应的显微镜载玻片上染色组织标本，用于根据染色程序在站（3）之间传送显微镜载片（7）的传送器（5），用于处理的显微镜载玻片的卸载站（10）和 用于根据数据程序控制处理操作的控制单元（19）。 该装置包括具有数字照相机（26）的照相站（25），用于在所提供的显微镜载片（7）上用完成的处理过的组织标本的背景光源进行自动拍摄。 相机连接到装置的控制单元（19），并且控制单元被布置成存储每个单独的组织样本的图片和位于相关微观滑块（7）上的信息，并且优选地还包括关于染色程序的信息 和试剂站（3）上的试剂的状态，用于将信息自动传输到用于结果分析的地方。

公开(公告)号：US08216846B2

公开(公告)日：2012-07-10

申请号：US11793558

申请日：2005-12-22

Applicant: Øystein Ljungmann ,  Torstein Ljungmann

Inventor： Øystein Ljungmann ,  Torstein Ljungmann

IPC: G01N35/00

CPC classification number: G01N1/312 ,  Y10T436/11 ,  Y10T436/2575

Abstract: A method and a system for use of treatment liquids in an apparatus for staining of tissue specimens on microscope slides, wherein the apparatus comprises a plurality of vessels (4) for receiving different liquids for treatment of the tissue specimens, a plurality of tanks (11) for treatment liquids, connecting lines (15) between the tanks and the vessels, a plurality of pumps (13) connected on the connecting lines, and a control unit for control of the apparatus and the liquid treatment by means of a data program, wherein the control unit is arranged for selective control of the relevant pumps (13), so that vessels (4) to be used in a staining process, are filled with liquid (14) at the start of the staining process, and so that the liquid-filled vessels (4) are emptied automatically when they are no longer to be used in the staining process.

Abstract translation: 一种用于在显微镜载片上染色组织样本的装置中的处理液的方法和系统，其中所述装置包括用于接收不同液体以处理组织样本的多个容器（4），多个容器（11 ），用于处理液体，罐和容器之间的连接管线（15），连接在连接管线上的多个泵（13）和用于通过数据程序控制装置和液体处理的控制单元， 其中所述控制单元被布置用于选择性地控制所述相关泵（13），使得在染色过程中使用的容器（4）在染色过程开始时被填充有液体（14），使得 液体填充容器（4）在染色过程中不再使用时自动排空。

公开(公告)号：US20120017830A1

公开(公告)日：2012-01-26

申请号：US13188839

申请日：2011-07-22

Applicant: Øystein Ljungmann ,  Torstein Ljungmann

Inventor： Øystein Ljungmann ,  Torstein Ljungmann

IPC: B05C9/12 ,  B05C11/00

CPC classification number: G01N1/312 ,  G02B21/34 ,  Y10T436/2575

Abstract: An apparatus for automatic execution of different treatment operations in connection with staining of tissue specimens on microscope slides, wherein the apparatus (1) comprises an assembly of vessels (4) for receiving different liquids for staining of the tissue specimens, a loading station (2) for microscope slides (28), a conveyor (5) for transfer of carriers with microscope slides from vessel to vessel in accordance with a treatment program, an unloading station (8) for treated microscope slides, and a control unit (18) for controlling the treatment operations in accordance with a data program. The apparatus comprises different levels (I, II) having units for execution of the relevant treatment operations. Thus, a first level (I) comprises the loading station (2) and the assembly of said vessels (4) with the appurtenant conveyor (5) and a second level (II) comprises a station (6) for application of cover glasses on the stained microscope slides (28), a succeeding station (7) for drying of the cover-slipped microscope slides, and the unloading station (8), a means (9) being provided for gripping and transfer of carriers (10) with stained microscope slides from the first level (I) to the cover-slipping station (6) on the second level (II).

Abstract translation: 一种用于自动执行与显微镜载玻片上的组织标本的染色相关的不同处理操作的装置，其中所述装置（1）包括用于接收用于染色组织样本的不同液体的容器（4）的组件，装载站（2 ）用于显微镜载玻片（28），用于根据处理程序将显微镜载玻片从容器转移到容器的传送器（5），用于处理的显微镜载片的卸载站（8）和用于 根据数据程序控制治疗操作。 该装置包括具有用于执行相关治疗操作的单元的不同级别（I，II）。 因此，第一级（I）包括装载站（2）和所述容器（4）与附属输送机（5）的组装，并且第二级（II）包括用于将盖玻片应用于 染色显微镜载玻片（28），用于干燥覆盖滑动的显微镜载玻片的后续站（7）和卸载站（8），提供用于夹持和转移带有染色的载体（10）的装置（9） 显微镜从第一级（I）滑动到第二级（II）上的盖板滑移台（6）。

公开(公告)号：US20060127276A1

公开(公告)日：2006-06-15

申请号：US10537826

申请日：2002-12-17

Applicant: Oystein Ljungmann ,  Torstein Ljungmann

Inventor： Oystein Ljungmann ,  Torstein Ljungmann

IPC: G01N35/00

CPC classification number: G01N1/312 ,  G01N2035/00039 ,  Y10T436/113332 ,  Y10T436/114165

Abstract: A Staining machine for treatment of tissue specimens on slides placed in baskets (9) includes a number of baths (7, 12) placed successively in a row (6 resp. 11), and a device for successive transport of the baskets in a transport path from one bath to the next one, the baskets (9) being transported from an input station (5) to an output station (14) in accordance with a predetermined treatment program. The machine includes at least two bath rows (6 resp. 11) placed juxtaposed and parallel with each other, the first bath row (6) extending from the input station (5) to an opposite end of this row, and second path row (11) extending from the output station (14) to an opposite end of this row. Further, the machine includes a first device (8, 21, 22) for transport of baskets (9) in a first transport path from the input station (5) to the opposite end of the first row (6), a second device (13, 15-19) for transport of baskets (9) in a second transport path towards the output station (14) from the opposite end of the second row (11), and a device for transfer of baskets between the transport paths of opposite ends of the rows belonging together.

Abstract translation: 用于处理放置在篮子（9）中的载玻片上的组织标本的染色机包括连续放置在一排（6或11）中的多个浴室（7,12））和用于在运输工具中连续运送篮子的装置 从一个浴槽到下一个洗涤槽的路径，根据预定的处理程序将篮子（9）从输入站（5）运送到输出站（14）。 该机器包括彼此并置并且平行放置的至少两个浴排（6或11），从输入站（5）延伸到该行的相对端的第一浴槽排（6）和第二路径排 11）从输出站（14）延伸到该行的相对端。 此外，机器包括用于在从输入站（5）到第一排（6）的相对端的第一传送路径中传送筐（9）的第一设备（8,21,22），第二设备 用于在第二传送路径中从第二排（11）的相对端向输出站（14）输送筐（9）的装置，以及用于在相对的传送路径之间传送筐的装置 属于一行的行尾。

公开(公告)号：US06382693B1

公开(公告)日：2002-05-07

申请号：US09714271

申请日：2000-11-17

Applicant: Torstein Ljungmann

Inventor： Torstein Ljungmann

IPC: B25J1506

CPC classification number: G02B21/34 ,  B25J15/0616

Abstract: A device for automatically attaching cover slips to microscope slides carrying a specimen for microscopic examination and a mounting medium, comprising a lifting mechanism (1) having a holder (2) in which there are mounted a pair of mutually spaced suction cups (3) extending in a vertical plane, and an abutment body (5) arranged between and outside of the suction cups (3) and having a downwards convexly curved abutment surface (6) for abutment against a cover slip (7) retained by the suction cups. The abutment body (5), at and end portion thereof situated laterally outside of the suction cups (3), is rotatably mounted in the holder (2) about an axis (9) extending transversely relative to the vertical plane, and the abutment body (5) is limitedly rotatable in the holder (2) to each side of an essentially horizontal intermediate position.

Abstract translation: 一种用于将盖板自动地附接到载体上用于显微镜检查的样本的显微镜载玻片的装置和一种安装介质，该装置包括具有保持器（2）的提升机构（1），其中安装有一对相互间隔开的吸盘（3） 以及设置在吸盘（3）的内部和外部的邻接体（5），并且具有向下的凸形弯曲的邻接表面（6），用于抵靠由吸盘保持的盖板（7）。 位于吸盘（3）的横向外侧的其邻接部分​​（5）和端部部分围绕相对于垂直平面横向延伸的轴线（9）可旋转地安装在保持器（2）中，并且抵接体 （5）在保持器（2）中有限地可旋转到基本上水平的中间位置的每一侧。

公开(公告)号：US6017495A

公开(公告)日：2000-01-25

申请号：US78825

申请日：1998-05-14

Applicant: Torstein Ljungmann

Inventor： Torstein Ljungmann

IPC: G01N1/30 ,  G01N1/31 ,  G02B21/34 ,  G01N35/10

CPC classification number: G02B21/34 ,  G01N1/312 ,  Y10T436/11 ,  Y10T436/112499 ,  Y10T436/113332 ,  Y10T436/114165

Abstract: A staining apparatus for staining of tissue specimens placed on microscope slides comprises a number of staining stations (4) and other working stations (1, 2, 3), where the staining stations (4) receive vessels (5) having liquid baths for receiving baskets containing microscope slides with the topical specimens, and a transport mechanism (17-20) having a hoisting device (17) arranged to be moved over the vessels (5) and to place baskets in or take these up from the vessels, and to transfer the baskets between the working stations (1-4) in accordance with a programme-controlled staining process. The vessels (5) are transparent and are arranged in a number of horizontal rows placed above one another on a stepped base like a tribune, the tribune having a gradient allowing visual inspection of the individual vessels (5) at the working stations (4) from a place of view in front of the apparatus.

Abstract translation: 用于染色放置在显微镜载片上的组织标本的染色装置包括多个染色站（4）和其他工作站（1,2,3），其中染色站（4）接收具有用于接收的液槽的容器（5） 包含具有局部标本的显微镜载玻片的篮子和具有布置成在容器（5）上移动并将筐放置在容器中或将其从容器中取出的提升装置（17）的输送机构（17-20） 根据程序控制的染色过程在工作站（1-4）之间转移篮子。 容器（5）是透明的，并且布置成多个水平排，这些水平行彼此相对放置在阶梯状的基座上，如论坛上，该论坛具有梯度，允许目视检查工作站（4）处的各个容器（5） 从设备前面的一个视角。

公开(公告)号：US08652408B2

公开(公告)日：2014-02-18

申请号：US13188839

申请日：2011-07-22

Applicant: Oystein Ljungmann ,  Torstein Ljungmann

Inventor： Oystein Ljungmann ,  Torstein Ljungmann

IPC: G01N21/00

CPC classification number: G01N1/312 ,  G02B21/34 ,  Y10T436/2575

Abstract: An apparatus for automatic execution of different treatment operations in connection with staining of tissue specimens on microscope slides, wherein the apparatus (1) comprises an assembly of vessels (4) for receiving different liquids for staining of the tissue specimens, a loading station (2) for microscope slides (28), a conveyor (5) for transfer of carriers with microscope slides from vessel to vessel in accordance with a treatment program, an unloading station (8) for treated microscope slides, and a control unit (18) for controlling the treatment operations in accordance with a data program. The apparatus comprises different levels (I, II) having units for execution of the relevant treatment operations. Thus, a first level (I) comprises the loading station (2) and the assembly of said vessels (4) with the appurtenant conveyor (5) and a second level (II) comprises a station (6) for application of cover glasses on the stained microscope slides (28), a succeeding station (7) for drying of the cover-slipped microscope slides, and the unloading station (8), a means (9) being provided for gripping and transfer of carriers (10) with stained microscope slides from the first level (I) to the cover-slipping station (6) on the second level (II).

Abstract translation: 一种用于自动执行与显微镜载玻片上的组织标本的染色相关的不同处理操作的装置，其中所述装置（1）包括用于接收用于染色组织样本的不同液体的容器（4）的组件，装载站（2 ）用于显微镜载玻片（28），用于根据处理程序将显微镜载玻片从容器转移到容器的传送器（5），用于处理的显微镜载片的卸载站（8）和用于 根据数据程序控制治疗操作。 该装置包括具有用于执行相关治疗操作的单元的不同级别（I，II）。 因此，第一级（I）包括装载站（2）和所述容器（4）与附属输送机（5）的组装，并且第二级（II）包括用于将盖玻片应用于 染色显微镜载玻片（28），用于干燥覆盖滑动的显微镜载玻片的后续站（7）和卸载站（8），提供用于夹持和转移带有染色的载体（10）的装置（9） 显微镜从第一级（I）滑动到第二级（II）上的盖板滑移台（6）。

公开(公告)号：US20130040339A1

公开(公告)日：2013-02-14

申请号：US13654259

申请日：2012-10-17

Applicant: Oystein Ljungmann ,  Torstein Ljungmann

Inventor： Oystein Ljungmann ,  Torstein Ljungmann

IPC: G01N1/30

CPC classification number: G01N1/312 ,  G02B21/34 ,  G02B21/365 ,  Y10T436/2575

Abstract: An apparatus for automatic execution of different treatment operations in connection with staining of tissue specimens on microscope slides, wherein the apparatus (1) comprises a loading station (2) for microscope slides (7) with tissue specimens, a number of reagent stations (3) for staining of the tissue specimens on supplied microscope slides, a conveyor (5) for transfer of microscope slides (7) between the stations (3) in accordance with a staining program, an unloading station (10) for treated microscope slides, and a control unit (19) for controlling the treatment operations in accordance with a data program. The apparatus comprise a photo station (25) with a digital camera (26) for automatic photographing with a background light source of the finished treated tissue specimens on supplied microscope slides (7). The camera is connected to the control unit (19) of the apparatus and the control unit is arranged to store the picture of each individual tissue specimen and information which is located on the relevant microscopic slide (7) and preferably also information about the staining program and status of reagents at the reagent stations (3) for automatic transmission of the information to a place for result analysis.

公开(公告)号：US20120309044A1

公开(公告)日：2012-12-06

申请号：US13493477

申请日：2012-06-11

Applicant: Øystein LJUNGMANN ,  Torstein Ljungmann

Inventor： Øystein LJUNGMANN ,  Torstein Ljungmann

IPC: G01N1/30

CPC classification number: G01N1/312 ,  Y10T436/11 ,  Y10T436/2575

Abstract: A method and a system for use of treatment liquids in an apparatus for staining of tissue specimens on microscope slides, wherein the apparatus comprises a plurality of vessels (4) for receiving different liquids for treatment of the tissue specimens, a plurality of tanks (11) for treatment liquids, connecting lines (15) between the tanks and the vessels, a plurality of pumps (13) connected on the connecting lines, and a control unit for control of the apparatus and the liquid treatment by means of a data program, wherein the control unit is arranged for selective control of the relevant pumps (13), so that vessels (4) to be used in a staining process, are filled with liquid (14) at the start of the staining process, and so that the liquid-filled vessels (4) are emptied automatically when they are no longer to be used in the staining process.

Abstract translation: 一种用于在显微镜载片上染色组织样本的装置中的处理液的方法和系统，其中所述装置包括用于接收不同液体以处理组织样本的多个容器（4），多个容器（11 ），用于处理液体，罐和容器之间的连接管线（15），连接在连接管线上的多个泵（13）和用于通过数据程序控制装置和液体处理的控制单元， 其中所述控制单元被布置用于选择性地控制所述相关泵（13），使得在染色过程中使用的容器（4）在染色过程开始时被填充有液体（14），使得 液体填充容器（4）在染色过程中不再使用时自动排空。

公开(公告)号：US20090027770A1

公开(公告)日：2009-01-29

申请号：US11793557

申请日：2005-12-22

Applicant: Oystein Ljungmann ,  Torstein Ljungmann

Inventor： Oystein Ljungmann ,  Torstein Ljungmann

IPC: G02B21/34

CPC classification number: G01N1/312 ,  B01L9/52 ,  B01L2300/0822 ,  G02B21/34

Abstract: A holding device for retaining a number of slides (12) with tissue specimens, wherein the surfaces of the microscope slides in retained position are located in a common plane, comprises an elongated hanger (1) having a clamping means (6) for releasable clamping of microscope slides (12) in a hanging position with the surfaces in said plane, the microscope slides being clamped at their upper end and by release from the clamping means (6) being free to fall from the hanger (1) because of their own weight. The clamping means (6) preferably is arranged to cooperate with a loading rack (7) having a supporting surface (14) for support of the current microscope slides (12) in said plan, the hanger (1) being able to be introduced into the rack (7) and the clamping means being able to actuated so that all microscope slides placed on the supporting surface are clamped in the holding device.

Abstract translation: 一种保持装置，用于保持具有组织样本的多个幻灯片（12），其中所述显微镜的表面在保持位置滑动位于公共平面中，包括细长悬挂器（1），其具有用于可释放夹紧的夹紧装置（6） 的显微镜载玻片（12）处于悬挂位置，其中所述平面中的表面，显微镜载玻片在其上端被夹紧，并且由于夹具（6）由于其自身而从吊架（1）自由地脱落 重量。 夹紧装置（6）优选地布置成与具有支撑表面（14）的装载架（7）配合，用于在所述平面图中支撑当前的显微镜载玻片（12），所述衣架（1）能够被引入 支架（7）和夹紧装置能够致动，使得放置在支撑表面上的所有显微镜载玻片夹紧在保持装置中。