公开(公告)号：US20060199728A1

公开(公告)日：2006-09-07

申请号：US10527899

申请日：2003-09-12

申请人： John Hartwig ,  Chutian Shu ,  Toshimichi Ohmura ,  Christoph Kiener ,  Fernando Lopez

发明人： John Hartwig ,  Chutian Shu ,  Toshimichi Ohmura ,  Christoph Kiener ,  Fernando Lopez

IPC分类号： B01J31/00

CPC分类号： C07B53/00 ,  B01J31/122 ,  B01J31/186 ,  B01J2231/44 ,  B01J2531/0266 ,  B01J2531/64 ,  B01J2531/66 ,  B01J2531/827 ,  C07B2200/07 ,  C07C209/08 ,  C07C209/16 ,  C07F9/657154 ,  C07F15/0033

摘要： The present invention is directed to a catalyst composition, comprising: (1) a catalyst precursor having the general structure MSXn wherein M is a transition metal selected from the group consisting of iridium, molybdenum, and tungsten; S is a coordinating ligand; X is a counterion; and n is an integer from 0 to 5; and (2) a phosphoramidite ligand having the structure wherein O—Cn—O is an aliphatic or aromatic diolate and wherein R1, R2, R3 and R4 are selected from the group consisting of substituted or unsubstituted aryl groups, substituted or unsubstituted heteroaryl groups, substituted or unsubstituted aliphatic groups, and combinations thereof, with the proviso that at least one of R1, R2, R3, or R4 must be a substituted or unsubstituted aryl or heteroaryl group. The present invention is also directed to activated catalysts made from the above catalyst composition, as well as methods of allylic amination and etherification using the above catalysts.

摘要翻译： 本发明涉及一种催化剂组合物，其包含：（1）具有一般结构MSX N的催化剂前体，其中M是选自铱，钼和钨的过渡金属; S是配位配体; X是抗衡离子 n为0〜5的整数。 和（2）具有以下结构的亚磷酰胺配体，其中OC n-O是脂族或芳族二醇酯，并且其中R 1，R 2， R 3和R 4选自取代或未取代的芳基，取代或未取代的杂芳基，取代或未取代的脂族基团及其组合，与 条件是R 1，R 2，R 3或R 4中的至少一个必须是取代的 或未取代的芳基或杂芳基。 本发明还涉及由上述催化剂组合物制备的活化催化剂，以及使用上述催化剂的烯丙基胺化和醚化的方法。

公开(公告)号：US07732365B2

公开(公告)日：2010-06-08

申请号：US10527899

申请日：2003-09-12

申请人： John F. Hartwig ,  Chutian Shu ,  Toshimichi Ohmura ,  Christoph Kiener ,  Fernando Garcia Lopez

发明人： John F. Hartwig ,  Chutian Shu ,  Toshimichi Ohmura ,  Christoph Kiener ,  Fernando Garcia Lopez

IPC分类号： B01J31/00 ,  B01J27/24 ,  B01J27/00 ,  B01J27/185

CPC分类号： C07B53/00 ,  B01J31/122 ,  B01J31/186 ,  B01J2231/44 ,  B01J2531/0266 ,  B01J2531/64 ,  B01J2531/66 ,  B01J2531/827 ,  C07B2200/07 ,  C07C209/08 ,  C07C209/16 ,  C07F9/657154 ,  C07F15/0033

摘要： The present invention is directed to a catalyst composition, comprising: (1) a catalyst precursor having the general structure MSXn wherein M is a transition metal selected from the group consisting of iridium, molybdenum, and tungsten; S is a coordinating ligand; X is a counterion; and n is an integer from 0 to 5; and (2) a phosphoramidite ligand having the structure wherein O—Cn—O is an aliphatic or aromatic diolate and wherein R1, R2, R3 and R4 are selected from the group consisting of substituted or unsubstituted aryl groups, substituted or unsubstituted heteroaryl groups, substituted or unsubstituted aliphatic groups, and combinations thereof, with the proviso that at least one of R1, R2, R3, or R4 must be a substituted or unsubstituted aryl or heteroaryl group. The present invention is also directed to activated catalysts made from the above catalyst composition, as well as methods of allylic amination and etherification using the above catalysts.

摘要翻译： 本发明涉及一种催化剂组合物，其包括：（1）具有一般结构MSXn的催化剂前体，其中M是选自铱，钼和钨的过渡金属; S是配位配体; X是抗衡离子 n为0〜5的整数。 和（2）具有以下结构的亚磷酰胺配体，其中O-Cn-O是脂族或芳族二醇酯，并且其中R 1，R 2，R 3和R 4选自取代或未取代的芳基，取代或未取代的杂芳基， 取代或未取代的脂族基团及其组合，条件是R 1，R 2，R 3或R 4中的至少一个必须是取代或未取代的芳基或杂芳基。 本发明还涉及由上述催化剂组合物制备的活化催化剂，以及使用上述催化剂的烯丙基胺化和醚化的方法。