公开(公告)号：US20110009929A1

公开(公告)日：2011-01-13

申请号：US12599259

申请日：2008-05-09

申请人： Richard L. Nuccitelli ,  Uwe F. Pliquett ,  Pamela Nuccitelli ,  Changyi Li ,  Saleh H. Sheikh

发明人： Richard L. Nuccitelli ,  Uwe F. Pliquett ,  Pamela Nuccitelli ,  Changyi Li ,  Saleh H. Sheikh

IPC分类号： A61N1/04

CPC分类号： A61N1/0452 ,  A61N1/0412 ,  A61N1/0456 ,  A61N1/0472 ,  A61N1/32

摘要： A medical instrument for delivering electrotherapy is provided. The instrument includes an outer support member having an open distal end and a base wall portion within the support member arranged to form a cup-like volume at the distal end. The instrument also includes at least one aperture formed in the cup-like volume for applying a suction to the cup-like region. The instrument further includes a first and a second electrode having at least a portion within the cup region or proximate to the cup region for providing an electric field in the cup region when a bias signal is applied between the first and second electrodes.

摘要翻译： 提供了一种用于提供电疗的医疗仪器。 仪器包括外部支撑构件，该外部支撑构件具有敞开的远端，并且支撑构件内的底壁部分布置成在远端处形成杯状体积。 仪器还包括形成在杯状体积中的至少一个孔，用于向杯状区域施加抽吸。 所述仪器还包括第一和第二电极，所述第一和第二电极具有在所述杯状区域内或靠近所述杯状区域的至少一部分，以在偏置信号施加在所述第一和第二电极之间时在所述杯状区域中提供电场。

公开(公告)号：US20090281411A1

公开(公告)日：2009-11-12

申请号：US12117598

申请日：2008-05-08

申请人： Richard Nuccitelli ,  Pamela Nuccitelli ,  Shr-Kai Liau ,  Uwe F. Pliquett ,  Changyi Li ,  Suman Narsing ,  Brian Athos ,  Saleh Sheikh

发明人： Richard Nuccitelli ,  Pamela Nuccitelli ,  Shr-Kai Liau ,  Uwe F. Pliquett ,  Changyi Li ,  Suman Narsing ,  Brian Athos ,  Saleh Sheikh

IPC分类号： A61B5/05

CPC分类号： A61B5/444 ,  A61B5/0051 ,  A61B5/04 ,  A61B5/442 ,  A61B5/6844 ,  A61B2560/04 ,  A61B2562/0214

摘要： The present invention provides a hand-held, noninvasive diagnostic device for measuring the electric fields in mammalian skin and other epithelial structures. The device includes an outer housing that contacts the skin, providing stability and allowing the device to move along with minor movement of the skin. Recessed within the outer housing is a probe that acts as a sensor to measure the electric field in the skin through an aperture in the bottom surface of the outer housing. By applying a series of known voltages while the probe is vibrating, the skin's local surface potential can be measured and the lateral electric field can be calculated from the spatial distribution of surface potential measurements. Active feedback is used to maintain a constant distance between the probe and the skin surface.

摘要翻译： 本发明提供了用于测量哺乳动物皮肤和其它上皮结构中的电场的手持式无创诊断装置。 该装置包括接触皮肤的外壳，提供稳定性并允许装置随着皮肤的轻微移动而移动。 嵌入在外壳内部的探头是用作传感器的探针，用于通过外壳底面的孔来测量皮肤中的电场。 通过在探头振动时应用一系列已知的电压，可以测量皮肤的局部表面电位，并可以从表面电位测量的空间分布计算横向电场。 主动反馈用于保持探头与皮肤表面之间的恒定距离。

公开(公告)号：US08694088B2

公开(公告)日：2014-04-08

申请号：US12117598

申请日：2008-05-08

申请人： Richard Nuccitelli ,  Pamela Nuccitelli ,  Shr-Kai Liau ,  Uwe F. Pliquett ,  Changyi Li ,  Suman Narsing ,  Brian Athos ,  Saleh Sheikh

发明人： Richard Nuccitelli ,  Pamela Nuccitelli ,  Shr-Kai Liau ,  Uwe F. Pliquett ,  Changyi Li ,  Suman Narsing ,  Brian Athos ,  Saleh Sheikh

IPC分类号： A61B5/00

CPC分类号： A61B5/444 ,  A61B5/0051 ,  A61B5/04 ,  A61B5/442 ,  A61B5/6844 ,  A61B2560/04 ,  A61B2562/0214

摘要： The present invention provides a hand-held, noninvasive diagnostic device for measuring the electric fields in mammalian skin and other epithelial structures. The device includes an outer housing that contacts the skin, providing stability and allowing the device to move along with minor movement of the skin. Recessed within the outer housing is a probe that acts as a sensor to measure the electric field in the skin through an aperture in the bottom surface of the outer housing. By applying a series of known voltages while the probe is vibrating, the skin's local surface potential can be measured and the lateral electric field can be calculated from the spatial distribution of surface potential measurements. Active feedback is used to maintain a constant distance between the probe and the skin surface.

摘要翻译： 本发明提供了用于测量哺乳动物皮肤和其它上皮结构中的电场的手持式无创诊断装置。 该装置包括接触皮肤的外壳，提供稳定性并允许装置随着皮肤的轻微移动而移动。 嵌入在外壳内部的探头是用作传感器的探针，用于通过外壳底面的孔来测量皮肤中的电场。 通过在探头振动时应用一系列已知的电压，可以测量皮肤的局部表面电位，并可以从表面电位测量的空间分布计算横向电场。 主动反馈用于保持探头与皮肤表面之间的恒定距离。

公开(公告)号：US08688227B2

公开(公告)日：2014-04-01

申请号：US12599259

申请日：2008-05-09

申请人： Richard L. Nuccitelli ,  Uwe F. Pliquett ,  Pamela Nuccitelli ,  Changyi Li ,  Saleh H. Sheikh

发明人： Richard L. Nuccitelli ,  Uwe F. Pliquett ,  Pamela Nuccitelli ,  Changyi Li ,  Saleh H. Sheikh

IPC分类号： A61B18/14

CPC分类号： A61N1/0452 ,  A61N1/0412 ,  A61N1/0456 ,  A61N1/0472 ,  A61N1/32

摘要： A medical instrument for delivering electrotherapy is provided. The instrument includes an outer support member having an open distal end and a base wall portion within the support member arranged to form a cup-like volume at the distal end. The instrument also includes at least one aperture formed in the cup-like volume for applying a suction to the cup-like region. The instrument further includes a first and a second electrode having at least a portion within the cup region or proximate to the cup region for providing an electric field in the cup region when a bias signal is applied between the first and second electrodes.

摘要翻译： 提供了一种用于提供电疗的医疗仪器。 仪器包括外部支撑构件，该外部支撑构件具有敞开的远端，并且支撑构件内的底壁部分布置成在远端处形成杯状体积。 仪器还包括形成在杯状体积中的至少一个孔，用于向杯状区域施加抽吸。 所述仪器还包括第一和第二电极，所述第一和第二电极具有在所述杯状区域内或靠近所述杯状区域的至少一部分，以在偏置信号施加在所述第一和第二电极之间时在所述杯状区域中提供电场。