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公开(公告)号:US5482710A
公开(公告)日:1996-01-09
申请号:US99876
申请日:1993-07-30
申请人: Craig S. Slavtcheff , Stephen R. Barrow , Vispi D. Kanga , Michael C. Cheney , Alexander Znaiden
发明人: Craig S. Slavtcheff , Stephen R. Barrow , Vispi D. Kanga , Michael C. Cheney , Alexander Znaiden
IPC分类号: A61K8/30 , A61K8/00 , A61K8/02 , A61K8/26 , A61K8/27 , A61K8/31 , A61K8/33 , A61K8/34 , A61K8/36 , A61K8/365 , A61K8/368 , A61K8/63 , A61K8/97 , A61K36/886 , A61Q19/00 , A61Q19/10 , A61K7/32 , A61K7/36 , A61K7/38 , A61K7/42
CPC分类号: A61K8/0229 , A61K8/0212 , A61K8/27 , A61K8/34 , A61K8/365 , A61K8/368 , A61K8/63 , A61K8/97 , A61Q19/00 , A61Q19/10 , A61Q19/007 , A61Q5/006 , Y10S424/05 , Y10S514/844 , Y10S514/845 , Y10S514/846 , Y10S514/847 , Y10S514/859
摘要: A cosmetic composition is provided which includes at least one keratolytic agent and a combination of water-soluble and water-insoluble anti-irritancy agents in a pharmaceutically acceptable carrier. Most effective is a combination of a C.sub.7 -C.sub.30 .beta.-hydroxy carboxylic acids such as salicylic acid with a C.sub.1 -C.sub.25 .alpha.-hydroxy carboxylic acid such as glycolic or lactic acids. The water-soluble anti-irritancy agent is preferably a salt of glycyrrhizinic acid. The water-insoluble anti-irritancy agent is preferably .alpha.-bisabolol, azulene or combinations thereof. Other performance components may include a C.sub.1 -C.sub.10 alkyl lactate and an antimicrobial agent such as a zinc or aluminum salt.
摘要翻译: 提供了一种化妆品组合物,其包含至少一种角质积水剂和药学上可接受的载体中的水溶性和水不溶性抗刺激剂的组合。 最有效的是C7-C30β-羟基羧酸如水杨酸与C1-C25α-羟基羧酸如乙醇酸或乳酸的组合。 水溶性抗刺激剂优选为甘草酸的盐。 水不溶性抗刺激剂优选为α-对映体,薁或其组合。 其它性能组分可包括乳酸C1-C10烷基酯和抗微生物剂如锌或铝盐。
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公开(公告)号:US5614201A
公开(公告)日:1997-03-25
申请号:US417417
申请日:1995-04-05
申请人: Craig S. Slavtcheff , Stephen R. Barrow , Vispi D. Kanga , Michael C. Cheney , Alexander Znaiden
发明人: Craig S. Slavtcheff , Stephen R. Barrow , Vispi D. Kanga , Michael C. Cheney , Alexander Znaiden
IPC分类号: A61K8/30 , A61K8/00 , A61K8/02 , A61K8/26 , A61K8/27 , A61K8/31 , A61K8/33 , A61K8/34 , A61K8/36 , A61K8/365 , A61K8/368 , A61K8/63 , A61K8/97 , A61K36/886 , A61Q19/00 , A61Q19/10 , A61K7/00 , A61K31/19 , A61K35/78
CPC分类号: A61K8/0229 , A61K8/0212 , A61K8/27 , A61K8/34 , A61K8/365 , A61K8/368 , A61K8/63 , A61K8/97 , A61Q19/00 , A61Q19/10 , A61Q19/007 , A61Q5/006 , Y10S424/05 , Y10S514/844 , Y10S514/845 , Y10S514/846 , Y10S514/847 , Y10S514/859
摘要: A cosmetic composition is provided which includes at least one keratolytic agent and a combination of water-soluble and water-insoluble anti-irritancy agents in a pharmaceutically acceptable carrier. Most effective is a combination of a C.sub.7 -C.sub.30 .beta.-hydroxy carboxylic acids such as salicylic acid with a C.sub.1 -C.sub.2 .alpha.-hydroxy carboxylic acid such as glycolic or lactic acids. The water-soluble anti-irritancy agent is preferably a salt of glycyrrhizinic acid. The water-insoluble anti-irritancy agent is preferably a-bisabolol, azulene or combinations thereof. Other performance components may include a C.sub.1 -C.sub.10 alkyl lactate and an antimicrobial agent such as a zinc or aluminum salt.
摘要翻译: 提供了一种化妆品组合物,其包含至少一种角质积水剂和药学上可接受的载体中的水溶性和水不溶性抗刺激剂的组合。 最有效的是C7-C30β-羟基羧酸如水杨酸与C1-C2α-羟基羧酸如乙醇酸或乳酸的组合。 水溶性抗刺激剂优选为甘草酸的盐。 所述水不溶性抗刺激剂优选为β-赤刺酚,薁或其组合。 其它性能组分可包括乳酸C1-C10烷基酯和抗微生物剂如锌或铝盐。
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