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公开(公告)号：US6156732A
公开(公告)日：2000-12-05
申请号：US387489
申请日：1999-09-01
CPC分类号： C07K5/0821 , A61K38/00 , Y10S514/822
摘要： Azole derivatives of formula (I): ##STR1## are disclosed as useful in treating platelet-mediated thrombotic disorders.
摘要翻译： 公开了式（I）的唑衍生物：可用于治疗血小板介导的血栓形成障碍。
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2.发明申请Substituted Quinoline Compounds For Use As Selective Estrogen Receptor Modulator 失效用作选择性雌激素受体调节剂的取代喹啉化合物公开(公告)号：US20070203180A1
公开(公告)日：2007-08-30
申请号：US10598246
申请日：2005-02-22
IPC分类号： A61K31/47 , A61K31/09 , A61K31/165 , C07C233/11 , C07C53/136 , C07D221/00 , C07D215/20 , C07C43/205 , A61K31/19 , A61K31/445
CPC分类号： C07D215/233 , C07C59/68 , C07D215/36
摘要： The present invention relates to novel compounds of formula (I) with a variety of therapeutic uses, more particularly novel substituted quinoline compounds particularly useful for selective estrogen receptor modulation.
摘要翻译： 本发明涉及具有多种治疗用途的新型式（I）化合物，更特别地涉及特别用于选择性雌激素受体调节的新颖取代的喹啉化合物。
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公开(公告)号：US20060009396A1
公开(公告)日：2006-01-12
申请号：US11227504
申请日：2005-09-15
CPC分类号： C07K5/06191 , C07K5/06095
摘要： The invention is directed to novel heteroaryl peptidomimetic compounds which are useful as thrombin receptor antagonists for the treatment of diseases associated with thrombosis, restenosis, hypertension, heart failure, arrhythmia, inflammation, angina, stroke, atherosclerosis, ischemic conditions, angiogenesis and related disorders, cancer, and neurodegenerative disorders. Pharmaceutical compositions comprising the substituted heteroaryl peptidomimetics of the present invention and methods of treating conditions mediated by the thrombin receptor are also disclosed.
摘要翻译： 本发明涉及可用作凝血酶受体拮抗剂用于治疗与血栓形成，再狭窄，高血压，心力衰竭，心律失常，炎症，心绞痛，中风，动脉粥样硬化，缺血性疾病，血管生成和相关疾病相关的疾病的新型杂芳族肽模拟化合物， 癌症和神经变性疾病。 还公开了包含本发明的取代的杂芳基肽模拟物的药物组合物和治疗由凝血酶受体介导的病症的方法。
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公开(公告)号：US6017890A
公开(公告)日：2000-01-25
申请号：US245739
申请日：1999-02-08
CPC分类号： C07K5/0821 , A61K38/00 , Y10S514/822
摘要： Azole derivatives of formula (I): ##STR1## are disclosed as useful in treating platelet-mediated thrombotic disorders.
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