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公开(公告)号：US20240139282A1
公开(公告)日：2024-05-02
申请号：US18484819
申请日：2023-10-11
摘要： The present disclosure relates to a stable aqueous composition of dalbavancin, the process for making such compositions and use of such compositions for treatment of a patient in need thereof.
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公开(公告)号：US20240139278A1
公开(公告)日：2024-05-02
申请号：US18392896
申请日：2023-12-21
发明人： Ivona Jasprica , Marcel Lagedroste
IPC分类号： A61K38/095 , A61K47/12 , A61K47/18 , A61K47/26
CPC分类号： A61K38/095 , A61K47/12 , A61K47/183 , A61K47/26
摘要： The present disclosure relates to a ready-to-administer formulation of oxytocin, its pharmaceutically acceptable salts, or derivatives thereof, as well as products including the formulation. Specifically, the disclosure is directed to storage stable ready-to-administer formulations of oxytocin, method of producing such formulations and uses thereof.
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公开(公告)号：US11759497B2
公开(公告)日：2023-09-19
申请号：US16642462
申请日：2018-08-28
IPC分类号： A61K38/12 , A61P31/04 , A61K9/19 , A61K31/198 , A61K31/4172 , A61K47/02 , A61K47/12 , A61K47/18 , A61K9/00 , A61K9/08
CPC分类号： A61K38/12 , A61K9/19 , A61K31/198 , A61K31/4172 , A61K47/02 , A61K47/12 , A61K47/183 , A61P31/04 , A61K9/0019 , A61K9/08
摘要： The present invention relates to compositions comprising daptomycin and at least one amino acid, methods of providing such compositions and the uses thereof.
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公开(公告)号：US20190240155A1
公开(公告)日：2019-08-08
申请号：US16343443
申请日：2017-10-17
发明人： Tina GJONI , Dubravka STRAZIC
CPC分类号： A61K9/08 , A61K38/12 , A61K47/10 , A61K47/14 , A61K47/20 , A61K47/26 , A61K47/44 , A61P31/04
摘要： The present invention relates to liquid pharmaceutical compositions comprising daptomycin, methods of providing such compositions and the use thereof. Provided herein are formulations comprising daptomycin, one or more polar protic solvents, and mixtures thereof. Formulations according to the present invention can further comprise polar aprotic solvent and/or source of calcium.
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公开(公告)号：US20180133286A1
公开(公告)日：2018-05-17
申请号：US15827719
申请日：2017-11-30
发明人： IVONA JASPRICA , SABINA KESER , KATARINA PINDRIC
CPC分类号： A61K38/14 , A61K9/0019 , A61K9/08 , A61K47/183
摘要： Solutions comprising a glycopeptide antibiotic, for example Vancomycin, and an amino acid or amino acid derivative such as N-acetyl-Glycine or N-acetyl-D-Alanine are provided. These solutions are stable or stabilized for long-term periods at conditions of normal use and storage, and can be formulated as pharmaceutical solutions for use in subjects. Methods of manufacturing and using these solutions are also provided, as are methods of stabilizing a glycopeptide antibiotic, for example Vancomycin, using amino acids or amino acid derivatives such as N-acetyl-Glycine or N-acetyl-D-Alanine.
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公开(公告)号：US20170218024A1
公开(公告)日：2017-08-03
申请号：US15324882
申请日：2015-06-29
发明人： VIDAR BJORNSTAD , SOLVI GUNNES , TORBEN KOCH , CLAES MELANDER
IPC分类号： C07K7/62
摘要： The present invention relates to novel low substituted polymyxins and compositions thereof.
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公开(公告)号：US20150352112A1
公开(公告)日：2015-12-10
申请号：US14760260
申请日：2014-01-09
IPC分类号： A61K31/506 , A61K9/08 , A61K47/48
CPC分类号： A61K31/506 , A61K9/08 , A61K47/6951 , B82Y5/00 , C08B37/0012 , C08B37/0015 , C08L5/16
摘要： The present invention relates to new voriconazole formulations comprising 2-hydroxypropyl-□-cyclodextrins and the preparation thereof.
摘要翻译： 本发明涉及包含2-羟丙基-β-环糊精及其制备的新的伏立康唑制剂。
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公开(公告)号：US20230158101A1
公开(公告)日：2023-05-25
申请号：US18151155
申请日：2023-01-06
发明人： Ivona Jasprica , Sabina Keser , Katarina Pindric
CPC分类号： A61K38/14 , A61K9/0019 , A61K47/183 , A61K9/08
摘要： Solutions comprising a glycopeptide antibiotic, for example Vancomycin, and an amino acid or amino acid derivative such as an N-acetyl amino acid are provided. These solutions are stable or stabilized for long-term periods at conditions of normal use and storage, and can be formulated as pharmaceutical solutions for use in subjects. Methods of manufacturing and using these solutions are also provided, as are methods of stabilizing a glycopeptide antibiotic, for example Vancomycin, using amino acids or amino acid derivatives such as N-acetyl amino acids.
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公开(公告)号：US20220354927A1
公开(公告)日：2022-11-10
申请号：US17860642
申请日：2022-07-08
发明人： Ivona Jasprica , Sabina Keser , Katarina Pindric
摘要： Solutions comprising a glycopeptide antibiotic, for example Vancomycin, and an amino acid or amino acid derivative such as N-acetyl-Glycine or N-acetyl-D-Alanine are provided. These solutions are stable or stabilized for long-term periods at conditions of normal use and storage, and can be formulated as pharmaceutical solutions for use in subjects. Methods of manufacturing and using these solutions are also provided, as are methods of stabilizing a glycopeptide antibiotic, for example Vancomycin, using amino acids or amino acid derivatives such as N-acetyl-Glycine or N-acetyl-D-Alanine.
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公开(公告)号：US20200254054A1
公开(公告)日：2020-08-13
申请号：US16642462
申请日：2018-08-28
IPC分类号： A61K38/12 , A61K31/198 , A61K31/4172 , A61K47/18 , A61K47/12 , A61K47/02 , A61P31/04 , A61K9/19
摘要： The present invention relates to compositions comprising daptomycin and at least one amino acid, methods of providing such compositions and the uses thereof.
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