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公开(公告)号：US08541010B2
公开(公告)日：2013-09-24
申请号：US13023804
申请日：2011-02-09
申请人： Sung-Bo Shim , Byoung-Young Jeon , Joo-Hyuck Lim , Jong-Keun Choi , Yong-Joon Joo , Jin-Hun Cho
发明人： Sung-Bo Shim , Byoung-Young Jeon , Joo-Hyuck Lim , Jong-Keun Choi , Yong-Joon Joo , Jin-Hun Cho
CPC分类号： A61K8/90 , A61K8/0241 , A61K8/11 , A61K8/553 , A61K8/676 , A61K8/97 , A61K2800/412 , A61K2800/56 , A61Q19/00
摘要： Disclosed is a cosmetic composition having a double-shell type nano-structure. More particularly, the nano-structure of the cosmetic composition includes: a water-soluble bioactive ingredient core; a core shell containing poly(ethyleneglycol)-poly(caprolactone)-poly(ethyleneglycol) (PE-PCL-PEG) triblock copolymer in order to include the bioactive ingredient core therein; and an outer shell containing phospholipids or derivatives thereof in order to enclose the core shell therein. Such a cosmetic composition improves stability of active components which are prone to oxidation, light degradation, heat degradation, etc., is formed in a nanoparticle size which in turn shows high transdermal absorption and is very useful to prepare a cosmetic composition stably encapsulating various bioactive ingredients with anti-wrinkle effects, whitening effects, and so forth.
摘要翻译： 公开了具有双壳型纳米结构的化妆品组合物。 更具体地，化妆品组合物的纳米结构包括：水溶性生物活性成分核心; 包含聚（乙二醇） - 聚（己内酯） - 聚（乙二醇）（PE-PCL-PEG）三嵌段共聚物的核壳，以包括其中的生物活性成分核心; 以及含有磷脂或其衍生物的外壳，以便将核壳包围在其中。 这种化妆品组合物提高了易于氧化，光降解，热降解等的活性成分的稳定性，其纳米颗粒大小形成，其又显示高透皮吸收，并且非常有用于制备稳定地包封各种生物活性物质的化妆品组合物 具有抗皱效果，美白效果等的成分。
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公开(公告)号：US20120015011A1
公开(公告)日：2012-01-19
申请号：US13023804
申请日：2011-02-09
申请人： Sung-Bo SHIM , Byoung-Young JEON , Joo-Hyuck LIM , Jong-Keun CHOI , Yong-Joon JOO , Jin-Hun CHO
发明人： Sung-Bo SHIM , Byoung-Young JEON , Joo-Hyuck LIM , Jong-Keun CHOI , Yong-Joon JOO , Jin-Hun CHO
CPC分类号： A61K8/90 , A61K8/0241 , A61K8/11 , A61K8/553 , A61K8/676 , A61K8/97 , A61K2800/412 , A61K2800/56 , A61Q19/00
摘要： Disclosed is a cosmetic composition having a double-shell type nano-structure. More particularly, the nano-structure of the cosmetic composition includes: a water-soluble bioactive ingredient core; a core shell containing poly(ethyleneglycol)-poly(caprolactone)-poly(ethyleneglycol) (PE-PCL-PEG) triblock copolymer in order to include the bioactive ingredient core therein; and an outer shell containing phospholipids or derivatives thereof in order to enclose the core shell therein. Such a cosmetic composition improves stability of active components which are prone to oxidation, light degradation, heat degradation, etc., is formed in a nanoparticle size which in turn shows high transdermal absorption and is very useful to prepare a cosmetic composition stably encapsulating various bioactive ingredients with anti-wrinkle effects, whitening effects, and so forth.
摘要翻译： 公开了具有双壳型纳米结构的化妆品组合物。 更具体地，化妆品组合物的纳米结构包括：水溶性生物活性成分核心; 包含聚（乙二醇） - 聚（己内酯） - 聚（乙二醇）（PE-PCL-PEG）三嵌段共聚物的核壳，以包括其中的生物活性成分核心; 以及含有磷脂或其衍生物的外壳，以便将核壳包围在其中。 这种化妆品组合物提高了易于氧化，光降解，热降解等的活性成分的稳定性，其纳米颗粒大小形成，其又显示高透皮吸收，并且非常有用于制备稳定地包封各种生物活性物质的化妆品组合物 具有抗皱效果，美白效果等的成分。
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