公开(公告)号：US11555016B2

公开(公告)日：2023-01-17

申请号：US17157916

申请日：2021-01-25

申请人： Yongbo Wang ,  Han Li ,  Gennian Mao ,  Bin Tian ,  Dan Yang ,  Chengyuan Liang ,  Xiuding Yang ,  Wenbo Yao ,  Guaiping Qiao ,  Nan Hui ,  Juan Li ,  Liang Xin ,  Jingyi Li ,  Ruina Bian

发明人： Yongbo Wang ,  Han Li ,  Gennian Mao ,  Bin Tian ,  Dan Yang ,  Chengyuan Liang ,  Xiuding Yang ,  Wenbo Yao ,  Guaiping Qiao ,  Nan Hui ,  Juan Li ,  Liang Xin ,  Jingyi Li ,  Ruina Bian

IPC分类号： C07D215/233 ,  A61P31/04

摘要： A compound with anti-drug resistant bacteria activity having the following formula (I): is disclosed. The methods of preparing the compound of formula (I) are also disclosed.

公开(公告)号：US11117859B1

公开(公告)日：2021-09-14

申请号：US17175575

申请日：2021-02-12

申请人： Dan Yang ,  Jingyi Li ,  Liang Xin ,  Qianqian Zhao ,  Liang Qi ,  Bin Tian ,  Jian Zha ,  Wenbo Yao ,  Gennian Mao ,  Han Li ,  Chunyang Shi ,  Yongbo Wang ,  Jingwen Xu

发明人： Dan Yang ,  Jingyi Li ,  Liang Xin ,  Qianqian Zhao ,  Liang Qi ,  Bin Tian ,  Jian Zha ,  Wenbo Yao ,  Gennian Mao ,  Han Li ,  Chunyang Shi ,  Yongbo Wang ,  Jingwen Xu

IPC分类号： C07C231/24 ,  C07C233/83 ,  C07C231/12

摘要： A compound with anti-drug resistant bacteria activity having the following formula (I) is disclosed. The methods of preparing the compound of formula (I) are also disclosed.

公开(公告)号：US10947182B1

公开(公告)日：2021-03-16

申请号：US16914326

申请日：2020-06-27

申请人： Han Li ,  Nan Hui ,  Chengyuan Liang ,  Xingke Ju ,  Guaiping Qiao ,  Juan Li ,  Yuanyuan He ,  Bin Tian ,  Yongbo Wang ,  Jingwen Xu ,  Liang Qi ,  Dan Yang ,  Qiangian Zhao ,  Yanjun Li ,  Qiao Zeng ,  Gennian Mao ,  Limei Wang

发明人： Han Li ,  Nan Hui ,  Chengyuan Liang ,  Xingke Ju ,  Guaiping Qiao ,  Juan Li ,  Yuanyuan He ,  Bin Tian ,  Yongbo Wang ,  Jingwen Xu ,  Liang Qi ,  Dan Yang ,  Qiangian Zhao ,  Yanjun Li ,  Qiao Zeng ,  Gennian Mao ,  Limei Wang

IPC分类号： C07C69/94

摘要： A compound having the formula (I): is disclosed. A method of preparing the compound of formula (I) is also disclosed.

公开(公告)号：US20190274610A1

公开(公告)日：2019-09-12

申请号：US16211187

申请日：2018-12-05

申请人： Yongbo Wang ,  Zhongsheng Ji

发明人： Yongbo Wang ,  Zhongsheng Ji

IPC分类号： A61B5/16 ,  A61B5/00

摘要： The present invention provides method for the quantitative or qualitive evaluation and ement of the user's cognitive ability, screening and improving pathological neurological ions. This is achieved by integrating and adapting current-in-practice cognitive assessment niques to an augmented/mixed reality system, which presents signals and stimulations in various forms to the user meanwhile recording user's surroundings, performance, and responses. The stimulations enhance users' cognitive functions, and the acquired data are evaluated by statistic methods to generate an evaluation that is more standardized and reflective of user's actual condition than current methods.

公开(公告)号：US11510905B1

公开(公告)日：2022-11-29

申请号：US17239583

申请日：2021-04-24

申请人： Chengyuan Liang ,  Wenjing Yang ,  Qianqian Zhao ,  Liang Xin ,  Jingyi Li ,  Dan Yang ,  Ruina Bian ,  Jie Zhang ,  Yuqing Zhao ,  Han Li ,  Bin Tian ,  Yongbo Wang ,  Liang Qi ,  Gennian Mao

发明人： Chengyuan Liang ,  Wenjing Yang ,  Qianqian Zhao ,  Liang Xin ,  Jingyi Li ,  Dan Yang ,  Ruina Bian ,  Jie Zhang ,  Yuqing Zhao ,  Han Li ,  Bin Tian ,  Yongbo Wang ,  Liang Qi ,  Gennian Mao

IPC分类号： C07D233/60 ,  A61K31/4164 ,  A61P31/04

摘要： A compound with anti-drug resistant bacteria activity having the following formula (I): is disclosed. The methods of preparing the compound of formula (I) are also disclosed.

公开(公告)号：US10941120B1

公开(公告)日：2021-03-09

申请号：US16909862

申请日：2020-06-23

申请人： Han Li ,  Nan Hui ,  Chengyuan Liang ,  Xingke Ju ,  Guaiping Qiao ,  Juan Li ,  Yuanyuan He ,  Bin Tian ,  Yongbo Wang ,  Jingwen Xu ,  Liang Qi ,  Dan Yang ,  Qianqian Zhao ,  Yanjun Li ,  Qiao Zeng ,  Gennian Mao ,  Limei Wang

发明人： Han Li ,  Nan Hui ,  Chengyuan Liang ,  Xingke Ju ,  Guaiping Qiao ,  Juan Li ,  Yuanyuan He ,  Bin Tian ,  Yongbo Wang ,  Jingwen Xu ,  Liang Qi ,  Dan Yang ,  Qianqian Zhao ,  Yanjun Li ,  Qiao Zeng ,  Gennian Mao ,  Limei Wang

IPC分类号： C07D239/545

摘要： A compound having the formula (I): is disclosed. A method of preparing the compound of formula (I) is also disclosed.

公开(公告)号：US11518740B2

公开(公告)日：2022-12-06

申请号：US17239575

申请日：2021-04-24

申请人： Qianqian Zhao ,  Jie Zhang ,  Liang Xin ,  Jingyi Li ,  Ruina Bian ,  Yuqing Zhao ,  Dan Yang ,  Han Li ,  Bin Tian ,  Yongbo Wang ,  Chengyuan Liang

发明人： Qianqian Zhao ,  Jie Zhang ,  Liang Xin ,  Jingyi Li ,  Ruina Bian ,  Yuqing Zhao ,  Dan Yang ,  Han Li ,  Bin Tian ,  Yongbo Wang ,  Chengyuan Liang

IPC分类号： C07C323/52 ,  C07C319/20

摘要： A compound with anti-drug resistant bacteria activity having the following formula (I): is disclosed. The methods of preparing the compound of formula (I) are also disclosed.

公开(公告)号：US20220348540A1

公开(公告)日：2022-11-03

申请号：US17239582

申请日：2021-04-24

申请人： Dan YANG ,  Jingyi LI ,  Liang XIN ,  Ruina BIAN ,  Jie ZHANG ,  Qianqian ZHAO ,  Yuqing ZHAO ,  Han LI ,  Bin TIAN ,  Yongbo WANG ,  Chengyuan LIANG ,  Liang QI ,  Gennian MAO

发明人： Dan YANG ,  Jingyi LI ,  Liang XIN ,  Ruina BIAN ,  Jie ZHANG ,  Qianqian ZHAO ,  Yuqing ZHAO ,  Han LI ,  Bin TIAN ,  Yongbo WANG ,  Chengyuan LIANG ,  Liang QI ,  Gennian MAO

IPC分类号： C07C323/52 ,  A61P31/04 ,  C07C319/28

摘要： A compound with anti-drug resistant bacteria activity having the formula (I): is disclosed. The methods of preparing the compound of formula (I) are also disclosed.

公开(公告)号：US20210347767A1

公开(公告)日：2021-11-11

申请号：US16871354

申请日：2020-05-11

申请人： Xingke JU ,  Chengyuan LIANG ,  Yuzhi LIU ,  Bin TIAN ,  Lei TIAN ,  Gennian MAO ,  Limei WANG ,  Yuanyuan HE ,  Yongbo WANG ,  Jingwen XU ,  Dan YANG ,  Liang QI ,  Wenbo YAO ,  Qianqian ZHAO ,  Han LI

发明人： Xingke JU ,  Chengyuan LIANG ,  Yuzhi LIU ,  Bin TIAN ,  Lei TIAN ,  Gennian MAO ,  Limei WANG ,  Yuanyuan HE ,  Yongbo WANG ,  Jingwen XU ,  Dan YANG ,  Liang QI ,  Wenbo YAO ,  Qianqian ZHAO ,  Han LI

IPC分类号： C07D409/14 ,  B01J27/24

摘要： A compound having the formula (I): is disclosed. A method of preparing the compound of formula (I) is also disclosed.

公开(公告)号：US10995053B1

公开(公告)日：2021-05-04

申请号：US16826045

申请日：2020-03-20

申请人： Han Li ,  Nan Hui ,  Bin Tian ,  Xingke Ju ,  Yuzhi Liu ,  Dan Yang ,  Jingwen Xu ,  Liang Qi ,  Qianqian Zhao ,  Yongbo Wang

发明人： Han Li ,  Nan Hui ,  Bin Tian ,  Xingke Ju ,  Yuzhi Liu ,  Dan Yang ,  Jingwen Xu ,  Liang Qi ,  Qianqian Zhao ,  Yongbo Wang

IPC分类号： C07C67/08 ,  B01J20/291 ,  B01J31/02

摘要： A compound having the formula (I): is disclosed. Methods of preparing the compound of formula (I) are also disclosed. The compound of formula (I) can be prepared by reacting a compound of formula (II) with a compound of formula (III) in an organic solvent with EDC (1-ethyl-3-(3-dimethylaminopropyl)carbodiimide). The compound of formula (I) can also be prepared by reacting the compound of formula (II) with the compound of formula (III) in 1-ethyl-3-methylimidazolium hexafluorophosphate as a solvent with silicomolybdic acid as a catalyst.