摘要:
A compound with anti-drug resistant bacteria activity having the following formula (I): is disclosed. The methods of preparing the compound of formula (I) are also disclosed.
摘要:
A device which has both educational and entertainment purposes. The device has a housing which allows multiple instances of the device to be stacked together. The device has a CPU, memory, storage, and a wireless module which allows communications with a base computer. The device also has a flat touch screen which serves as the user interface. The touch screen also serves as the video display for the device. Each device is approximately the size of a conventional building block. Variants include having some sides equipped with protuberance and some sides are equipped with voids. The protuberances of one device is constructed and arranged to interlockingly mate with the voids of another device. The device may be used in conjunction with multiple types of applications which have both educational and entertainment uses. The device may be used to receive images, data, commands, etc. from the base computer and the device may be used in conjunction with other similar devices.
摘要:
Current resource data may be continuously and automatically received indicative of a current state of resources that are used to deliver healthcare to a plurality of patients associated with a healthcare enterprise. The current resource data may be automatically used to update a healthcare enterprise simulation model. The healthcare enterprise simulation model may be executed to automatically generate a predicted future state of the resources. A resource request may then be received, and a resource assignment engine may automatically assign a particular resource to the resource request based at least in part on the predicted future state of the resources.
摘要:
The present invention relates to a semiconductor device packaged at the wafer level such that an entire packaged device is formed prior to separation of individual devices. The semiconductor device package includes a semiconductor chip having one or more bonding pads associated with the chip and a protective layer bonded over the semiconductor chip. An insulation layer is positioned on at least side edges and a lower surface of the semiconductor chip. Interconnection/bump metallization is positioned adjacent one or more side edges of the semiconductor chip and is electrically connected to at least one bonding pad. A compact image sensor package can be formed that is vertically integrated with a digital signal processor and memory chip along with lenses and a protective cover.
摘要:
A handle for a computing device having a touch screen, wherein the handle is affixed to the computing device, and the handle is made of material that is suitable for gripping by an infant and the handle is of a specific size range such that the handle is capable of being gripped by an infant.
摘要:
Provided herein are self-assembling compounds that can form ion channels in lipid bilayers or cell membranes and ion-channel-forming compositions comprising the self-assembling compounds. Also provided are methods of making and using the ion channels formed from a plurality of molecules of the self-assembling compounds. Further, provided are methods of treating or preventing conditions and diseases that are related to the dysfunction of ion channels, including chloride channels.
摘要:
Methods and software applications targeted to and for use by infant users. Various activities are presented to infant users through a touch-screen based monitor and, depending on the input entered by infant users, emotionally positive or emotionally negative indications are presented to the infant user. The emotionally positive indications are designed to reinforce desirable results caused by the infant user's input while the emotionally negative indications are designed to discourage undesirable result from the infant user's input. Various environments and activities based on these environments and areas are provided to the infant user by way of the monitor.
摘要:
Provided herein are fluorophore compounds including rhodol and rhodamine compounds which can be used as fluorescent labels and/or fluorogenic probes and methods of making same. Provided also herein are methods that can be used to track, measure, detect, or screen biological species such as protein, DNA, enzyme, antibody, organelle, cell, tissue, drug, hormone, nucleotide, nucleic acid, polysaccharide or lipid in living organisms. Specifically, the methods include the steps of contacting any of the fluorophore compounds, rhodol compounds and rhodamine compounds disclosed herein with the biological species to form one or more fluorescent compounds, and measuring fluorescence properties of the fluorescent compounds. Provided also herein are high-throughput screening fluorescent methods for detecting or screening biological species.
摘要:
A robust system for automating the tuning and maintenance of decision-making systems is described. A configurable multi-stage mutation-based evolutionary algorithm optimally tunes the decision thresholds and internal parameters of fuzzy rule-based and case-based systems that decide the risk categories of insurance applications. The tunable parameters have a critical impact on the coverage and accuracy of decision-making, and a reliable method to optimally tune these parameters is critical to the quality of decision-making and maintainability of these systems.