公开(公告)号：US20100055762A1

公开(公告)日：2010-03-04

申请号：US12225411

申请日：2006-03-24

Applicant: Toyohiko Ariga ,  Taiichiro Seki ,  Go Watanabe ,  Hiroto Nakashima ,  Nobuaki Okumura ,  Yuichi Hasebe

Inventor： Toyohiko Ariga ,  Taiichiro Seki ,  Go Watanabe ,  Hiroto Nakashima ,  Nobuaki Okumura ,  Yuichi Hasebe

IPC: C12N5/07 ,  C12N9/72

CPC classification number: C12N5/067 ,  A61K38/49 ,  C12N2501/113 ,  C12N2501/70 ,  C12N2506/03

Abstract: This invention relates to an agent for promoting differentiation of an ES cell, preferably an agent for promoting differentiation of an ES cell into a hepatocyte or a prophylactic agent for teratoma, comprising uPA.Furthermore this invention relates to a method of promoting differentiation of an ES cell, preferably a method of promoting differentiation of an ES cell into a hepatocyte, comprising the step of contacting uPA with the ES cell, or a method of preparing a hepatocyte comprising the step of contacting uPA with an ES cell to differentiate the ES cell into a hepatocyte.

Abstract translation: 本发明涉及一种用于促进ES细胞分化的试剂，优选用于促进ES细胞分化为肝细胞或用于畸胎瘤的预防药物的试剂，其包含uPA。 此外，本发明涉及促进ES细胞分化的方法，优选促进ES细胞分化成肝细胞的方法，包括使uPA与ES细胞接触的步骤，或制备包含该步骤的肝细胞的方法 将uPA与ES细胞接触以将ES细胞分化为肝细胞。

公开(公告)号：US20050051710A1

公开(公告)日：2005-03-10

申请号：US10922966

申请日：2004-08-23

Applicant: Yuichi Hasebe ,  Kiichiro Shinokura

Inventor： Yuichi Hasebe ,  Kiichiro Shinokura

IPC: G02B3/00 ,  G02B13/00 ,  G02B13/18 ,  H01J3/14

CPC classification number: G02B13/002 ,  G02B13/18

Abstract: A light signal receiving apparatus receives a light signal transmitted from a light signal transmitting apparatus disposed in a household room, and supplies video and audio information to a video equipment, and an audio equipment including an amplifier and a speaker. The light signal receiving apparatus includes an optical system condensing the light signal on a light-receiving element with a condensing lens. The light-receiving element is disposed nearer the condensing lens in relation to a focusing point of the condensing lens, and the condensing lens includes a non-spherical surface shape strongly distributing, on the light-receiving element, an intensity distribution on a light-receiving element disposed plane of an incident light obliquely incident with respect to an optical axis of the condensing lens within a range of predetermined angles. Thereby, the light signal incident on the condensing lens within a large range can be received at a predetermined light receiving intensity.

Abstract translation: 光信号接收装置接收从设置在家庭室的光信号发送装置发送的光信号，并将视频和音频信息提供给视频设备，以及包括放大器和扬声器的音频设备。 光信号接收装置包括将光接收元件上的光信号与聚光透镜聚光的光学系统。 光接收元件相对于聚光透镜的聚焦点设置得更靠近聚光透镜，并且聚光透镜在光接收元件上包括强光分布的非球形表面形状， 在预定角度的范围内相对于聚光透镜的光轴倾斜入射的入射光的接收元件设置面。 因此，可以以预定的光接收强度接收入射在大范围内的聚光透镜的光信号。

公开(公告)号：US08168430B2

公开(公告)日：2012-05-01

申请号：US12225411

申请日：2006-03-24

Applicant: Toyohiko Ariga ,  Taiichiro Seki ,  Go Watanabe ,  Hiroto Nakashima ,  Yuichi Hasebe

Inventor： Toyohiko Ariga ,  Taiichiro Seki ,  Go Watanabe ,  Hiroto Nakashima ,  Yuichi Hasebe

IPC: C12N5/00 ,  A01N63/00

CPC classification number: C12N5/067 ,  A61K38/49 ,  C12N2501/113 ,  C12N2501/70 ,  C12N2506/03

Abstract: This invention relates to an agent for promoting differentiation of an ES cell, preferably an agent for promoting differentiation of an ES cell into a hepatocyte or a prophylactic agent for teratoma, comprising uPA. Furthermore this invention relates to a method of promoting differentiation of an ES cell, preferably a method of promoting differentiation of an ES cell into a hepatocyte, comprising the step of contacting uPA with the ES cell, or a method of preparing a hepatocyte comprising the step of contacting uPA with an ES cell to differentiate the ES cell into a hepatocyte.

Abstract translation: 本发明涉及一种用于促进ES细胞分化的试剂，优选用于促进ES细胞分化为肝细胞或用于畸胎瘤的预防药物的试剂，其包含uPA。 此外，本发明涉及促进ES细胞分化的方法，优选促进ES细胞分化为肝细胞的方法，包括使uPA与ES细胞接触的步骤，或包含步骤 将uPA与ES细胞接触以将ES细胞分化为肝细胞。