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    EASILY DOSABLE SOLID PREPARATION
    1.
    发明申请
    EASILY DOSABLE SOLID PREPARATION 有权
    易于实用的固体制剂

    公开(公告)号：US20140308359A1

    公开(公告)日：2014-10-16

    申请号：US14345708

    申请日：2011-09-30

    申请人： Yumio Kudou ,  Kuniomi Warabino ,  Hiromitsu Ito

    发明人： Yumio Kudou ,  Kuniomi Warabino ,  Hiromitsu Ito

    IPC分类号： A61K9/28 ,  A61K31/522 ,  A61K31/5383

    CPC分类号： A61K9/2866 ,  A61K9/0053 ,  A61K9/2072 ,  A61K9/2813 ,  A61K9/282 ,  A61K9/2826 ,  A61K9/284 ,  A61K9/286 ,  A61K9/2886 ,  A61K31/522 ,  A61K31/5383

    摘要： It has been desired to develop a coating composition, which is used for an orally-administered preparation having an improved administering property, and/or an easily administrable preparation that does not affect dissolution property. The present invention provides a coating composition comprising: a first thickener selected from the group consisting of a carboxyvinyl polymer and sodium alginate; a polyvalent metal compound; at least one type of a second thickener selected from the group consisting of xanthan gum, guar gum and sodium alginate, with the proviso that when the first thickener is sodium alginate the second thickener is not sodium alginate; and sucralose.

    摘要翻译： 期望开发用于具有改善的施用性能的口服制剂的涂料组合物和/或不影响溶解性能的易于施用的制剂。 本发明提供一种涂料组合物，其包含：选自羧乙烯基聚合物和藻酸钠的第一增稠剂; 多价金属化合物; 至少一种选自黄原胶，瓜尔胶和海藻酸钠的第二增稠剂，条件是当第一增稠剂为藻酸钠时，第二增稠剂不是藻酸钠; 和三氯蔗糖。

    Easily administrable solid preparation
    3.
    发明申请
    Easily administrable solid preparation 审中-公开
    易于施用的固体制剂

    公开(公告)号：US20120082723A1

    公开(公告)日：2012-04-05

    申请号：US13200759

    申请日：2011-09-30

    申请人： Yumio Kudou ,  Kuniomi Warabino

    发明人： Yumio Kudou ,  Kuniomi Warabino

    IPC分类号： A61K9/36 ,  A61K47/36 ,  A61K47/38 ,  A61K9/34 ,  A61K9/32 ,  A61K47/32 ,  A61K9/00

    CPC分类号： A61K9/2866 ,  A61K9/2072 ,  A61K9/2813 ,  A61K9/2826 ,  A61K9/284 ,  A61K9/286 ,  A61K9/2886 ,  A61K31/522 ,  A61K31/5383

    摘要： It is an object to provide a coating composition, which is used for an orally-administered preparation, the administering property of which has been improved, and/or an easily administrable preparation that does not affect dissolution property. The aforementioned object can be achieved using a coating composition comprising a first thickener selected from the group consisting of a carboxyvinyl polymer and sodium alginate, a polyvalent metal compound, and at least one type of a second thickener selected from the group consisting of xanthan gum, guar gum and sodium alginate, with the proviso that when the first thickener is sodium alginate the second thickener is not sodium alginate, or using a coating composition comprising, as thickeners, hydroxypropylmethylcellulose and sugar or sugar alcohol having a solubility at 20° C. of 30 or more.

    摘要翻译： 本发明的目的是提供一种涂料组合物，其用于口服制剂，其施用性能得到改善，和/或不影响溶解性能的易于施用的制剂。 上述目的可以使用包含选自羧乙烯基聚合物和藻酸钠的第一增稠剂，多价金属化合物和至少一种选自黄原胶， 瓜尔胶和海藻酸钠，条件是当第一增稠剂为海藻酸钠时，第二增稠剂不是藻酸钠，或者使用包含作为增稠剂的羟丙基甲基纤维素和在20℃下具有溶解度的糖或糖醇的涂料组合物 30以上。