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公开(公告)号：US08481324B2
公开(公告)日：2013-07-09
申请号：US13131345
申请日：2009-12-02
Applicant: Hossam Haick , Zaid Abassi , Farid Nakhoul
Inventor： Hossam Haick , Zaid Abassi , Farid Nakhoul
CPC classification number: G01N33/497 , B82Y15/00 , G01N33/0034 , G01N2800/347 , Y10T436/145555 , Y10T436/172307 , Y10T436/173845 , Y10T436/174614 , Y10T436/200833 , Y10T436/25875
Abstract: The present invention provides a system containing an array of chemically sensitive sensors based on coated single walled carbon nanotubes, for measuring volatile organic compounds indicative of renal failure. Methods of breath analysis for diagnosing chronic, acute and end-stage renal failure are disclosed.
Abstract translation: 本发明提供一种包含基于涂覆的单壁碳纳米管的化学敏感传感器阵列的系统，用于测量指示肾衰竭的挥发性有机化合物。 公开了用于诊断慢性，急性和终末期肾衰竭的呼吸分析方法。
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公开(公告)号：US20110244584A1
公开(公告)日：2011-10-06
申请号：US13131345
申请日：2009-12-02
Applicant: Hossam Haick , Zaid Abassi , Farid Nakhoul
Inventor： Hossam Haick , Zaid Abassi , Farid Nakhoul
CPC classification number: G01N33/497 , B82Y15/00 , G01N33/0034 , G01N2800/347 , Y10T436/145555 , Y10T436/172307 , Y10T436/173845 , Y10T436/174614 , Y10T436/200833 , Y10T436/25875
Abstract: The present invention provides a system comprising an array of chemically sensitive sensors based on coated single walled carbon nanotubes, for measuring volatile organic compounds indicative of renal failure. Methods of breath analysis for diagnosing chronic, acute and end-stage renal failure are disclosed.
Abstract translation: 本发明提供一种系统，其包括基于涂覆的单壁碳纳米管的化学敏感传感器阵列，用于测量指示肾衰竭的挥发性有机化合物。 公开了用于诊断慢性，急性和终末期肾衰竭的呼吸分析方法。
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Patent Agency Ranking
3.发明申请公开(公告)号：US20080090915A1
公开(公告)日：2008-04-17
申请号：US11874788
申请日：2007-10-18
Applicant: Moussa Youdim , Ofer Binah , Zaid Abassi , Yaron Barac
Inventor： Moussa Youdim , Ofer Binah , Zaid Abassi , Yaron Barac
IPC: A61K31/137 , A61P9/00
CPC classification number: A61K31/137
Abstract: Propargylamine, propargylamine derivatives including N-propargyl-1-aminoindan, enantiomers and analogs thereof, and pharmaceutically acceptable salts thereof, are useful for prevention or attenuation of anthracycline-induced cardiotoxicity.
Abstract translation: 炔丙胺，包括N-炔丙基-1-氨基茚满的炔丙胺衍生物，其对映体及其类似物及其药学上可接受的盐可用于预防或减弱蒽环类诱发的心脏毒性。
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公开(公告)号：US20070082958A1
公开(公告)日：2007-04-12
申请号：US11244150
申请日：2005-10-06
Applicant: Ofer Binah , Zaid Abassi , Moussa Youdim
Inventor： Ofer Binah , Zaid Abassi , Moussa Youdim
IPC: A61K31/135 , A61K31/185
CPC classification number: A61K31/135 , A61K31/131
Abstract: Propargylamine, propargylamine derivatives including N-propargyl-1-aminoindan and analogs thereof, and pharmaceutically acceptable salts thereof, are useful for prevention or treatment of renal failure.
Abstract translation: 炔丙胺，包括N-炔丙基-1-氨基茚满的炔丙胺衍生物及其类似物及其药学上可接受的盐可用于预防或治疗肾衰竭。
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公开(公告)号：US20060287401A1
公开(公告)日：2006-12-21
申请号：US11449862
申请日：2006-06-09
Applicant: Moussa Youdim , Ofer Binah , Zaid Abassi , Yaron Barac
Inventor： Moussa Youdim , Ofer Binah , Zaid Abassi , Yaron Barac
IPC: A61K31/135
Abstract: Propargylamine, propargylamine derivatives including N-propargyl-1-aminoindan, enantiomers and analogs thereof, and pharmaceutically acceptable salts thereof, are useful for prevention or treatment of cardiovascular disorders, diseases and conditions.
Abstract translation: 炔丙胺，包括N-炔丙基-1-氨基茚满的炔丙胺衍生物，其对映体及其类似物及其药学上可接受的盐可用于预防或治疗心血管疾病，疾病和病症。
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6.发明申请Compositions and methods for treatment of cardiovascular disorders and diseases 审中-公开用于治疗心血管疾病和疾病的组合物和方法公开(公告)号：US20050171210A1
公开(公告)日：2005-08-04
申请号：US10952367
申请日：2004-09-29
Applicant: Moussa Youdim , Ofer Binah , Zaid Abassi , Yaron Barac
Inventor： Moussa Youdim , Ofer Binah , Zaid Abassi , Yaron Barac
IPC: A61K31/13 , A61K31/135 , A61K31/205 , A61K31/27
CPC classification number: A61K31/136 , A61K31/13
Abstract: Propargylamine, propargylamine derivatives including N-propargyl-1-aminoindan and analogs thereof, and pharmaceutically acceptable salts thereof, are useful for prevention or treatment of cardiovascular disorders and diseases.
Abstract translation: 炔丙胺，包括N-炔丙基-1-氨基茚丹及其类似物的炔丙胺衍生物及其药学上可接受的盐可用于预防或治疗心血管疾病和疾病。
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7.发明申请COMPOSITIONS AND METHODS FOR AMELIORATING RENAL DYSFUNCTION INDUCED BY RENAL HYPOPERFUSION OR ACUTE KIDNEY INJURY 审中-公开通过肾功能不全或急性感染引起的肾功能不全的组合物和方法公开(公告)号：US20130296331A1
公开(公告)日：2013-11-07
申请号：US13989204
申请日：2011-11-24
Applicant: Zaid Abassi , Bishar Bishara
Inventor： Zaid Abassi , Bishar Bishara
IPC: A61K31/4985
CPC classification number: A61K31/4985 , A61K31/353 , A61K31/4995 , A61K31/506 , A61K31/519 , A61K31/522 , A61K31/53
Abstract: The invention provides compositions and methods for ameliorating renal dysfunction induced by renal hypoperfusion or acute kidney injury, resulting for example from increased intra-abdominal pressure, using phosphodiesterase inhibitors, more particularly phosphodiesterase type inhibitors, or pharmaceutically acceptable salts or solvates thereof.
Abstract translation: 本发明提供了用于改善由肾脏低灌注或急性肾损伤引起的肾功能障碍的组合物和方法，其导致例如使用磷酸二酯酶抑制剂，更特别是磷酸二酯酶抑制剂，或其药学上可接受的盐或溶剂化物，引起腹内压升高。
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