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公开(公告)号:US08473319B2
公开(公告)日:2013-06-25
申请号:US13407326
申请日:2012-02-28
Applicant: Yumiko Christine Yokoi , Nancy V. Lang , Justin Craig Field , Andrew Philip Gillibrand , Steven K. Chu , Hong (Laura) Lin
Inventor: Yumiko Christine Yokoi , Nancy V. Lang , Justin Craig Field , Andrew Philip Gillibrand , Steven K. Chu , Hong (Laura) Lin
IPC: G06Q40/00
CPC classification number: G06Q10/06398 , G06Q10/06
Abstract: A system and method for encouraging the exchange of feedback in an enterprise. An example method includes providing one or more user interface controls for configuring a feedback reminder to automatically include predetermined insight pertaining to a potential participant in a future feedback exchange; sending the feedback reminder to a messaging system or application; providing a user option to view content of the feedback reminder; and displaying the feedback reminder in response to user selection of the first user option. Another user option enables selection of particular insight, derived from a talent management system, for inclusion in the feedback reminder. The messaging system may include an email application or an application for displaying a worklist.
Abstract translation: 鼓励企业交流反馈的制度和方法。 示例性方法包括提供一个或多个用户界面控件,用于配置反馈提醒器,以在将来的反馈交换中自动地包括与潜在参与者有关的预定洞察; 将反馈提醒发送到消息系统或应用程序; 提供用户选项来查看反馈提醒的内容; 以及响应于用户选择所述第一用户选项显示所述反馈提醒。 另一个用户选项可以选择源自人才管理系统的特定见解,以便纳入反馈提醒。 消息系统可以包括用于显示工作列表的电子邮件应用程序或应用程序。
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公开(公告)号:US20060063228A1
公开(公告)日:2006-03-23
申请号:US11149309
申请日:2005-06-09
Applicant: Marion Kasaian , Lioudmila Tchistiakova , Geertruida Veldman , Kimberly Marquette , Xiang-Yang Tan , Debra Donaldson , Laura Lin , Tania Shane , Amy Tam , Eric Feyfant , Nancy Wood , Lori Fitz , Angela Widom , Kevin Parris , Samuel Goldman , Jose Saldanha
Inventor: Marion Kasaian , Lioudmila Tchistiakova , Geertruida Veldman , Kimberly Marquette , Xiang-Yang Tan , Debra Donaldson , Laura Lin , Tania Shane , Amy Tam , Eric Feyfant , Nancy Wood , Lori Fitz , Angela Widom , Kevin Parris , Samuel Goldman , Jose Saldanha
CPC classification number: C07K16/244 , A61K2039/505 , C07K2299/00 , C07K2317/24 , C07K2317/55 , C07K2317/56 , C07K2317/73 , C07K2317/732 , C07K2317/76 , C07K2317/92
Abstract: This application relates to antibodies, e.g., humanized antibodies, and antigen-binding fragments thereof, that bind to interleukin-13 (IL-13), in particular, human IL-13, and their uses in regulating immune responses mediated by IL-13. The antibodies disclosed herein are useful in diagnosing, preventing, and/or treating a subject, e.g., a human patient, one or more IL-13-associated disorders, e.g., respiratory disorders (e.g., asthma); atopic disorders (e.g., allergic rhinitis); inflammatory and/or autoimmune conditions of the skin (e.g., atopic dermatitis), and gastrointestinal organs (e.g., inflammatory bowel diseases (IBD)), as well as fibrotic and cancerous disorders.
Abstract translation: 本申请涉及结合白细胞介素-13(IL-13)特别是人IL-13的抗体,例如人源化抗体及其抗原结合片段及其在调节由IL-13介导的免疫应答中的用途 。 本文公开的抗体可用于诊断,预防和/或治疗受试者,例如人类患者,一种或多种IL-13相关疾病,例如呼吸系统疾病(例如哮喘); 特应性疾病(如过敏性鼻炎); 皮肤的炎症和/或自身免疫病症(例如特应性皮炎)和胃肠器官(例如炎性肠病(IBD))以及纤维化和癌性疾病。
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公开(公告)号:US20120303421A1
公开(公告)日:2012-11-29
申请号:US13407326
申请日:2012-02-28
Applicant: Yumiko Christine Yokoi , Nancy V. Lang , Justin Craig Field , Andrew Philip Gillibrand , Steven K. Chu , Hong (Laura) Lin
Inventor: Yumiko Christine Yokoi , Nancy V. Lang , Justin Craig Field , Andrew Philip Gillibrand , Steven K. Chu , Hong (Laura) Lin
IPC: G06Q10/00
CPC classification number: G06Q10/06398 , G06Q10/06
Abstract: A system and method for encouraging the exchange of feedback in an enterprise. An example method includes providing one or more user interface controls for configuring a feedback reminder to automatically include predetermined insight pertaining to a potential participant in a future feedback exchange; sending the feedback reminder to a messaging system or application; providing a user option to view content of the feedback reminder; and displaying the feedback reminder in response to user selection of the first user option. Another user option enables selection of particular insight, derived from a talent management system, for inclusion in the feedback reminder. The messaging system may include an email application or an application for displaying a worklist.
Abstract translation: 鼓励企业交流反馈的制度和方法。 示例性方法包括提供一个或多个用户界面控件,用于配置反馈提醒器,以在将来的反馈交换中自动地包括与潜在参与者有关的预定洞察; 将反馈提醒发送到消息系统或应用程序; 提供用户选项来查看反馈提醒的内容; 以及响应于用户选择所述第一用户选项显示所述反馈提醒。 另一个用户选项可以选择源自人才管理系统的特定见解,以便纳入反馈提醒。 消息系统可以包括用于显示工作列表的电子邮件应用程序或应用程序。
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公开(公告)号:US20090136111A1
公开(公告)日:2009-05-28
申请号:US11944620
申请日:2007-11-25
Applicant: Kadri Nizar Jabri , Renuka Uppaluri , Yan Laura Lin , Huanzhong Li , Gopal Biligeri Avinash , John Michael Sabol
Inventor: Kadri Nizar Jabri , Renuka Uppaluri , Yan Laura Lin , Huanzhong Li , Gopal Biligeri Avinash , John Michael Sabol
IPC: A61B6/00
Abstract: A system and method of diagnosing a medical condition in a patient from accessing image data and non-image data of a patient, analyzing the combination of image data and non-image data to generate an output with image findings and a risk assessment for diagnosing certain medical conditions in the patient. The image data may be acquired from an image acquisition system. The non-image data may include clinical data of the patient and may be acquired from a user interface, an electronic medical record, and/or findings from an expert system from previous imaging sessions.
Abstract translation: 一种诊断病人医疗状况的系统和方法,用于访问患者的图像数据和非图像数据,分析图像数据和非图像数据的组合以产生具有图像发现的输出和用于诊断某些 病人的病情。 图像数据可以从图像采集系统获取。 非图像数据可以包括患者的临床数据,并且可以从用户界面,电子医疗记录和/或来自先前成像会话的专家系统的发现获得。
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公开(公告)号:US20070048785A1
公开(公告)日:2007-03-01
申请号:US11149025
申请日:2005-06-09
Applicant: Laura Lin , Kevin Parris , Amy Sze Tam , Xiang-Yang Tan , Tania Shane , John Dumas , James Wilhelm , Mark Stahl , Lidia Mosyak , Zhixiang Hu
Inventor: Laura Lin , Kevin Parris , Amy Sze Tam , Xiang-Yang Tan , Tania Shane , John Dumas , James Wilhelm , Mark Stahl , Lidia Mosyak , Zhixiang Hu
CPC classification number: C07K16/244 , A61K2039/505 , C07K2317/24 , C07K2317/52 , C07K2317/56 , C07K2317/565 , C07K2317/76 , C07K2317/92
Abstract: Anti-IL-13 antibodies, crystals of anti-IL-13 antibodies, IL-13 polypeptide/anti-IL-13 antibody complexes, crystals of IL-13 polypeptide/anti-IL-13 antibody complexes, IL-13Rα1 polypeptide/IL-13 polypeptide/anti-IL-13 antibody complexes, crystals of IL-13Rα1 polypeptide/IL-13 polypeptide/anti-IL-13 antibody complexes, and related methods and software systems are disclosed.
Abstract translation: 抗IL-13抗体,抗IL-13抗体晶体,IL-13多肽/抗IL-13抗体复合物,IL-13多肽/抗IL-13抗体复合物的结晶,IL-13Rα1多肽/ IL -13多肽/抗IL-13抗体复合物,IL-13Rα1多肽/ IL-13多肽/抗IL-13抗体复合物的晶体,以及相关方法和软件系统。
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公开(公告)号:US07584087B2
公开(公告)日:2009-09-01
申请号:US11099958
申请日:2005-04-06
Applicant: Zhang Bao Xu , Stephane Olland , Scott Wolfrom , Karl Malakian , Laura Lin , Mark Stahl , Julie Lee , Lori Fitz , Rita Greco , Divya Chaudhary , William Stuart Somers , Lidia Mosyak
Inventor: Zhang Bao Xu , Stephane Olland , Scott Wolfrom , Karl Malakian , Laura Lin , Mark Stahl , Julie Lee , Lori Fitz , Rita Greco , Divya Chaudhary , William Stuart Somers , Lidia Mosyak
CPC classification number: C12N9/1205 , C07K2299/00 , C12Q1/485 , G01N33/564 , G01N33/57426 , G01N2500/04
Abstract: A three-dimensional structure of human protein kinase C theta (PKCθ) can be used in methods of designing an agent that interacts with PKCθ. The agent can be an inhibitor of PKCθ activity.
Abstract translation: 人蛋白激酶Cθ(PKCθ)的三维结构可用于设计与PKCθ相互作用的试剂的方法中。 该药物可以是PKCθ活性的抑制剂。
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公开(公告)号:US20060003431A1
公开(公告)日:2006-01-05
申请号:US11099958
申请日:2005-04-06
Applicant: Zhang Xu , Stephane Olland , Scott Wolfrom , Karl Malakian , Laura Lin , Mark Stahl , Julie Lee , Lori Fitz , Rita Greco , Divya Chaudhary , William Somers , Lidia Mosyak
Inventor: Zhang Xu , Stephane Olland , Scott Wolfrom , Karl Malakian , Laura Lin , Mark Stahl , Julie Lee , Lori Fitz , Rita Greco , Divya Chaudhary , William Somers , Lidia Mosyak
IPC: G06F19/00 , G01N33/48 , G01N33/50 , C12N9/12 , A61K31/553
CPC classification number: C12N9/1205 , C07K2299/00 , C12Q1/485 , G01N33/564 , G01N33/57426 , G01N2500/04
Abstract: A three-dimensional structure of protein kinase C theta (PKCθ) can be used in methods of designing an agent that interacts with PKCθ. The agent can be an inhibitor of PKCθ activity.
Abstract translation: 蛋白激酶Cθ(PKCθ)的三维结构可用于设计与PKCθ相互作用的试剂的方法。 该药物可以是PKCθ活性的抑制剂。
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