公开(公告)号：US08431708B2

公开(公告)日：2013-04-30

申请号：US12613770

申请日：2009-11-06

Applicant: Ta-Chau Chang ,  Chih-Chien Cho ,  Cheng-Chung Chang ,  Chi-Chih Kang ,  Zi-Fu Wang

Inventor： Ta-Chau Chang ,  Chih-Chien Cho ,  Cheng-Chung Chang ,  Chi-Chih Kang ,  Zi-Fu Wang

IPC: C07D209/82 ,  A61K31/454

CPC classification number: C07D401/14 ,  C09K11/06 ,  C09K2211/1029

Abstract: A compound of formula (I): in which R1-R8, A, B, X, Y, m, and n are as defined herein. Also disclosed is a method for detecting a cancer cell using a compound of formula I.

Abstract translation: 式（I）化合物：其中R 1 -R 8，A，B，X，Y，m和n如本文所定义。 还公开了使用式I化合物检测癌细胞的方法。

公开(公告)号：US20130005720A1

公开(公告)日：2013-01-03

申请号：US13172975

申请日：2011-06-30

Applicant: Ta-Chau CHANG ,  Zi-Fu Wang ,  Chih-Chien Cho ,  Wei-Chun Huang ,  Jen-Fei Chu

Inventor： Ta-Chau CHANG ,  Zi-Fu Wang ,  Chih-Chien Cho ,  Wei-Chun Huang ,  Jen-Fei Chu

IPC: A61K31/5383 ,  C12N5/09 ,  A61P35/02 ,  A61K31/473 ,  A61K31/4745 ,  A61P35/00 ,  A61K31/4545 ,  C12N5/071

CPC classification number: A61K31/403

Abstract: This invention relates to a pharmaceutical composition for treating cancer, comprising an effective amount of a compound represented by formula (I): wherein R is —CCOCCOCC— or —CCOCCOCCOCC—; and a pharmaceutical acceptable carrier. This invention also relates to a method for treating cancer, comprising administering a therapeutically effective amount of said compound to a subject; and a method for stabilizing G4 structure of telomere by using this compound.

Abstract translation: 本发明涉及一种治疗癌症的药物组合物，其包含有效量的由式（I）表示的化合物：其中R是-CCOCCOCC-或-COCOCCOCOCOCC-; 和药物可接受的载体。 本发明还涉及一种治疗癌症的方法，包括向受试者施用治疗有效量的所述化合物; 以及通过使用该化合物稳定端粒的G4结构的方法。

公开(公告)号：US20110111429A1

公开(公告)日：2011-05-12

申请号：US12613770

申请日：2009-11-06

Applicant: Ta-Chau Chang ,  Chih-Chien Cho ,  Cheng-Chung Chang ,  Chi-Chih Kang ,  Zi-Fu Wang

Inventor： Ta-Chau Chang ,  Chih-Chien Cho ,  Cheng-Chung Chang ,  Chi-Chih Kang ,  Zi-Fu Wang

IPC: G01N33/53 ,  C07D211/68

CPC classification number: C07D401/14 ,  C09K11/06 ,  C09K2211/1029

Abstract: A compound of formula (I): in which R1-R8, A, B, X, Y, m, and n are as defined herein. Also disclosed is a method for detecting a cancer cell using a compound of formula I.

Abstract translation: 式（I）化合物：其中R 1 -R 8，A，B，X，Y，m和n如本文所定义。 还公开了使用式I化合物检测癌细胞的方法。