公开(公告)号：US20240218427A1

公开(公告)日：2024-07-04

申请号：US18399109

申请日：2023-12-28

Applicant: 10x Genomics, Inc.

Inventor： David Sukovich ,  Hardeep Pal Singh ,  Lauren Gutgesell ,  Ace George Santiago ,  Benton Veire ,  Anuj Patel

IPC: C12Q1/6823 ,  G01N33/58 ,  G01N33/68

CPC classification number: C12Q1/6823 ,  G01N33/58 ,  G01N33/6857 ,  G01N2458/10

Abstract: Provided herein are methods for spatial analysis of proteins and/or nucleic acids by capturing a capture handle sequence and/or a connected probe to a capture domain of a capture probe on a spatial array. In some instances, a reagent medium including a monovalent or divalent salt, ethylene carbonate, and/or glycerol is used in the disclosed methods.