公开(公告)号：US20230194469A1

公开(公告)日：2023-06-22

申请号：US17923436

申请日：2021-05-18

Applicant: 10x Genomics, Inc.

Inventor： Augusto Manuel Tentori ,  Hanyoup KIM ,  Felice Alessio Bava ,  Rajiv Bharadwaj

IPC: G01N27/447

CPC classification number: G01N27/44713 ,  G01N27/44782

Abstract: Various implementations of electrophoretic systems and instruments are provided to improve electrophoresis and ease of use. Various electrophoretic systems and instruments utilize different electrode designs that can result in uniform electromigration of analytes. The electrophoretic systems and instrumentations optimize the size and/or location of electrodes relative to a sample, thereby increasing uniformity of electric field and reducing or minimizing drift of analyte migration. In addition, the electrophoresis systems and instruments provide a solution to conveniently check for electrical connections in the systems and instruments, and alert users of potential improper electrical connections, prior to performing electrophoresis.

公开(公告)号：US20230265491A1

公开(公告)日：2023-08-24

申请号：US17923007

申请日：2021-04-30

Applicant: 10x Genomics, Inc.

Inventor： Augusto Manuel Tentori ,  Hanyoup KIM ,  Rajiv Bharadwaj

IPC: C12Q1/6837 ,  C12Q1/6869 ,  C12Q1/6841

CPC classification number: C12Q1/6837 ,  C12Q1/6869 ,  C12Q1/6841 ,  C12Q2600/16

Abstract: Provided herein are methods and systems for determining the location of one or more analytes in a biological sample with electrophoresis analyte transfer modes.

公开(公告)号：US20220280933A1

公开(公告)日：2022-09-08

申请号：US17751267

申请日：2022-05-23

Applicant: 10x Genomics, Inc.

Inventor： Rajiv BHARADWAJ ,  Hanyoup KIM ,  Bill Kengli LIN ,  Marissa PENNELL ,  Alireza SALMANZADEH ,  Martin SAUZADE ,  Tobias Daniel WHEELER

IPC: B01L3/02 ,  B01L3/00

Abstract: Devices, systems, and their methods of use, for generating droplets are provided. The devices, systems, and methods may include transporting a first liquid through an outlet of a channel and causing relative motion of the outlet and an interface of a second liquid to produce droplets of the first liquid in the second liquid. The devices, systems, and methods may also include illuminating a portion of the liquid as the liquid exits from an outlet. The invention also provides methods, devices, and systems for changing the size of a droplet and for eliminating a droplet from a plurality of droplets.