公开(公告)号：US11525154B2

公开(公告)日：2022-12-13

申请号：US15559117

申请日：2016-03-18

Applicant: 3M INNOVATIVE PROPERTIES COMPANY

Inventor： Jobst T. Jaeger ,  Jeffrey D. Smith ,  Waleri Wischnepolski ,  Henning Reuter ,  Giuseppe M. Bommarito ,  Manjiri T. Kshirsagar ,  Scott D. Lehman ,  Edward I. Stamm, Jr. ,  Guenter M. Zilligen

IPC: B01L3/02 ,  B01L3/00 ,  B01L99/00 ,  C12Q1/22 ,  C12Q1/04 ,  G01N33/543

Abstract: Devices for detecting microorganism strains or target cellular analytes are provided. The device includes a filter holder, the filter holder comprising a tip portion; a nonwoven article disposed on the tip portion of the filter holder; and an adaptor attacked to the filter holder, the adaptor defining an aperture. Methods of detecting microorganisms and/or cellular analytes in a fluid sample using the devices are also provided. The method includes obtaining the device; placing a lumened or cannulated device in fluid communication with the device; and passing a fluid sample suspected of containing at least one microorganism strain or target cellular analyte from the lumened or cannulated device through the device and contacting the nonwoven article. The method further includes contacting the nonwoven article with at least one detection reagent and detecting the presence of the at least one microorganism strain or target cellular analyte concentrated by the nonwoven article. Kits and systems including the devices are also provided.

公开(公告)号：US20180051312A1

公开(公告)日：2018-02-22

申请号：US15559117

申请日：2016-03-18

Applicant: 3M INNOVATIVE PROPERTIES COMPANY

Inventor： Jobst T. Jaeger ,  Jeffrey D. Smith ,  Waleri Wischnepolski ,  Henning Reuter ,  Giuseppe M. Bommarito ,  Manjiri T. Kshirsagar ,  Scott D. Lehman ,  Edward I. Stamm, Jr. ,  Guenter M. Zilligen

IPC: C12Q1/22 ,  B01L3/02 ,  B01L3/00 ,  C12Q1/04 ,  G01N33/543

CPC classification number: C12Q1/22 ,  B01L3/0275 ,  B01L3/5029 ,  B01L2200/028 ,  B01L2200/0684 ,  B01L2300/0681 ,  B01L2300/123 ,  B01L2400/0478 ,  B01L2400/0605 ,  C12Q1/04 ,  G01N33/54386

Abstract: Devices for detecting microorganism strains or target cellular analytes are provided. The device includes a filter holder, the filter holder comprising a tip portion; a nonwoven article disposed on the tip portion of the filter holder; and an adaptor attacked to the filter holder, the adaptor defining an aperture. Methods of detecting microorganisms and/or cellular analytes in a fluid sample using the devices are also provided. The method includes obtaining the device; placing a lumened or cannulated device in fluid communication with the device; and passing a fluid sample suspected of containing at least one microorganism strain or target cellular analyte from the lumened or cannulated device through the device and contacting the nonwoven article. The method further includes contacting the nonwoven article with at least one detection reagent and detecting the presence of the at least one microorganism strain or target cellular analyte concentrated by the nonwoven article. Kits and systems including the devices are also provided.