公开(公告)号：US20180263920A1

公开(公告)日：2018-09-20

申请号：US15537579

申请日：2015-12-17

Applicant: 3M INNOVATIVE PROPERTIES COMPANY

Inventor： Amy Preszler Prince ,  Adam S. Cantor ,  Stephen J. Woehrle ,  John R. Hart ,  James P. DiZio ,  Sarah A. Sykora ,  Michael L. Husberg

IPC: A61K9/70 ,  A61K31/4468

CPC classification number: A61K9/7061 ,  A61K9/7069 ,  A61K31/4468

Abstract: A transdermal drug delivery device includes a backing and an adhesive composition disposed on the backing. The adhesive composition includes a copolymer having at least 50 percent by weight C4 to C10 alkyl acrylate units, based on the total weight of the copolymer, and one or more second monomer units selected from the group consisting of vinyl acetate, acrylamide, ethyl acrylate, methyl acrylate, and N-vinyl-2-pyrrolidone. The C4 to C10 alkyl acrylate and the one or more second monomer units together make up at least 98 percent by weight of the copolymer. The adhesive composition further includes a skin permeation enhancer in a range from 5 percent to 25 percent by weight, based on the total weight of the adhesion composition, and fentanyl. The adhesive composition is substantially free of undissolved fentanyl. A method of treating a mammal including placing the transdermal drug delivery device on the mammal's skin is also disclosed.

公开(公告)号：US10329384B2

公开(公告)日：2019-06-25

申请号：US15025740

申请日：2014-09-24

Applicant: 3M INNOVATIVE PROPERTIES COMPANY

Inventor： Richard G. Hansen ,  James P. DiZio ,  Junkang Liu ,  David S. Hays ,  Deena M. Conrad-Vlasak ,  Timothy A. Peterson ,  Sarah A. Sykora

IPC: A61K9/70 ,  C09J183/12 ,  A61K31/167 ,  A61L24/00 ,  C08G77/46 ,  A61K47/34 ,  A61F13/02 ,  A61L15/58 ,  A61L24/04

Abstract: Silicone-polyether copolymers, adhesives and medical articles comprising same, and methods of making same. The silicone-polyether copolymer composition can include a backbone composition having a first (silicone) segment and a second (polyether) segment connected randomly via at least one of an oxamide linkage and a urea linkage. The method of making the silicone-polyether copolymer composition can include combining: a) a first (silicone) precursor; b) a second (polyether) precursor; and c) at least one of a diisocyanate and an oxalate compound.

公开(公告)号：US20210268473A1

公开(公告)日：2021-09-02

申请号：US17258204

申请日：2019-06-28

Applicant: 3M INNOVATIVE PROPERTIES COMPANY

Inventor： Gregory W. Sitton ,  Fuxia Sun ,  Sarah A. Sykora ,  Leslie M. Horton

IPC: B01J20/08 ,  B01J20/281 ,  C01G25/00 ,  A23L5/20 ,  A23K10/30 ,  B01D11/02 ,  B01D15/42

Abstract: A Ti—Al—Zr—O metal oxide having the formula TixAlyZrzOn, wherein x is independently 2-10, y is independently 0.5-6, z is independently 2-10, and n is independently 2x+3y/2+2z. A method of separating a mycotoxin from a matrix using a Ti—Al—Zr—O metal oxide.

公开(公告)号：US20160215100A1

公开(公告)日：2016-07-28

申请号：US15025740

申请日：2014-09-24

Applicant: 3M INNOVATIVE PROPERTIES COMPANY

Inventor： Richard G. Hansen ,  James P. DiZio ,  Junkang Liu ,  David S. Hays ,  Deena M. Conrad-Vlasak ,  Timothy A. Peterson ,  Sarah A. Sykora

IPC: C08G77/46 ,  A61L24/04 ,  A61K31/167 ,  A61L24/00 ,  C09J183/12 ,  A61K9/70

CPC classification number: C08G77/46 ,  A61F13/0253 ,  A61K9/7069 ,  A61K31/167 ,  A61K47/34 ,  A61L15/58 ,  A61L24/0015 ,  A61L24/046 ,  A61L2300/208 ,  A61L2300/404 ,  C09J183/12 ,  C08L83/04

Abstract: Silicone-polyether copolymers, adhesives and medical articles comprising same, and methods of making same. The silicone-polyether copolymer composition can include a backbone composition having a first (silicone) segment and a second (polyether) segment connected randomly via at least one of an oxamide linkage and a urea linkage. The method of making the silicone-polyether copolymer composition can include combining: a) a first (silicone) precursor; b) a second (polyether) precursor; and c) at least one of a diisocyanate and an oxalate compound.

Abstract translation: 含硅聚醚共聚物，包含它们的粘合剂和医疗制品及其制备方法。 硅氧烷 - 聚醚共聚物组合物可以包括具有第一（硅氧烷）链段和第二（聚醚）片段的骨架组合物，其随机地通过氧化胺键和脲键中的至少一种连接。 制备硅氧烷 - 聚醚共聚物组合物的方法可以包括：a）第一（硅氧烷）前体; b）第二（聚醚）前体; 和c）至少一种二异氰酸酯和草酸酯化合物。