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公开(公告)号：US20100184865A1
公开(公告)日：2010-07-22
申请号：US12751134
申请日：2010-03-31
IPC分类号： A61K31/135 , A61P3/04
CPC分类号： A61K31/137 , C07C211/27 , C07C211/36 , C07C215/60
摘要： A method of promoting weight loss in animals or humans by administering thereto a therapeutically effective amount of a mixture of RR-ractopamine and SR-ractopamine is disclosed.
摘要翻译： 公开了通过向其施用治疗有效量的RR-莱克多巴胺和SR-莱克多巴胺的混合物来促进动物或人类体重减轻的方法。
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公开(公告)号：US20090143480A1
公开(公告)日：2009-06-04
申请号：US12221780
申请日：2008-08-06
IPC分类号： A61K31/137 , A61P21/00 , C07C215/56
CPC分类号： A61K31/137 , C07C211/27 , C07C211/36 , C07C215/60
摘要： A method of promoting or improving the feed efficiency and the muscle-to-fat ratio in animals by administering to the animals a therapeutically effective amount of a mixture of RR-ractopamine and SR-ractopamine is disclosed. Manufacturing methods for making RR/SR-ractopamine are presented.
摘要翻译： 公开了通过向动物施用治疗有效量的RR-莱克多巴胺和SR-莱克多巴胺的混合物来促进或改善动物的饲料效率和肌肉与脂肪比的方法。 提出制备RR / SR-莱克多巴胺的制备方法。
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公开(公告)号：US08071653B2
公开(公告)日：2011-12-06
申请号：US12751134
申请日：2010-03-31
IPC分类号： A61K31/135
CPC分类号： A61K31/137 , C07C211/27 , C07C211/36 , C07C215/60
摘要： A method of promoting weight loss in animals or humans by administering thereto a therapeutically effective amount of a mixture of RR-ractopamine and SR-ractopamine is disclosed.
摘要翻译： 公开了通过向其施用治疗有效量的RR-莱克多巴胺和SR-莱克多巴胺的混合物来促进动物或人类体重减轻的方法。
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公开(公告)号：US07723392B2
公开(公告)日：2010-05-25
申请号：US12221780
申请日：2008-08-06
IPC分类号： A61K31/135
CPC分类号： A61K31/137 , C07C211/27 , C07C211/36 , C07C215/60
摘要： A method of promoting or improving the feed efficiency and the muscle-to-fat ratio in animals by administering to the animals a therapeutically effective amount of a mixture of RR-ractopamine and SR-ractopamine is disclosed. Manufacturing methods for making RR/SR-ractopamine are presented.
摘要翻译： 公开了通过向动物施用治疗有效量的RR-莱克多巴胺和SR-莱克多巴胺的混合物来促进或改善动物的饲料效率和肌肉与脂肪比的方法。 提出制备RR / SR-莱克多巴胺的制备方法。
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公开(公告)号：US08450519B2
公开(公告)日：2013-05-28
申请号：US13422144
申请日：2012-03-16
申请人： Milan Soukup , Karl Reuter , Florian Stolz , Viktor Meier , Jofzsef Balint , Mark Kantor
发明人： Milan Soukup , Karl Reuter , Florian Stolz , Viktor Meier , Jofzsef Balint , Mark Kantor
CPC分类号： C07C235/34 , C07B2200/07 , C07C51/377 , C07C57/13 , C07C57/66 , C07C59/64 , C07C59/90
摘要： The invention relates to a process for preparing chiral octenoic acid derivatives, which constitute important intermediates in the preparation of medicament active ingredients, and also to novel intermediates which are used in the process for preparing the octenoic acid derivatives mentioned.
摘要翻译： 本发明涉及制备手性辛烯酸衍生物的方法，其在制备药物活性成分中构成重要的中间体，还涉及用于制备所述辛烯酸衍生物的方法中的新型中间体。
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公开(公告)号：US20120178959A1
公开(公告)日：2012-07-12
申请号：US13422144
申请日：2012-03-16
申请人： Milan SOUKUP , Karl Reuter , Florian Stolz , Viktor Meier , Jofzsef Balint , Mark Kantor
发明人： Milan SOUKUP , Karl Reuter , Florian Stolz , Viktor Meier , Jofzsef Balint , Mark Kantor
IPC分类号： C07C57/13 , C07C69/593
CPC分类号： C07C235/34 , C07B2200/07 , C07C51/377 , C07C57/13 , C07C57/66 , C07C59/64 , C07C59/90
摘要： The invention relates to a process for preparing chiral octenoic acid derivatives, which constitute important intermediates in the preparation of medicament active ingredients, and also to novel intermediates which are used in the process for preparing the octenoic acid derivatives mentioned.
摘要翻译： 本发明涉及制备手性辛烯酸衍生物的方法，其在制备药物活性成分中构成重要的中间体，还涉及用于制备所述辛烯酸衍生物的方法中的新型中间体。
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公开(公告)号：US20110077398A1
公开(公告)日：2011-03-31
申请号：US12934669
申请日：2009-03-20
申请人： Karl Reuter , Viktor Meier , Florian Stolz , Dieter Krimmer , Cees Winninps
发明人： Karl Reuter , Viktor Meier , Florian Stolz , Dieter Krimmer , Cees Winninps
IPC分类号： C07D313/00 , C07D413/02
CPC分类号： C07D313/00 , C07H17/08
摘要： Described is pentamycin in a purity exceeding 95%, certain polymorphs and solvates of pentamycin, processes for their manufacture, and a method for decreasing the rate of degradation of pentamycin.
摘要翻译： 描述了纯度超过95％的戊霉素，某些多晶型物和戊霉素的溶剂合物，其制备方法，以及降低戊霉素降解速率的方法。
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公开(公告)号：US08445708B2
公开(公告)日：2013-05-21
申请号：US12091795
申请日：2006-10-27
申请人： Milan Soukup , Karl Reuter , Florian Stolz , Viktor Meier , Jofzsef Balint , Mark Kantor
发明人： Milan Soukup , Karl Reuter , Florian Stolz , Viktor Meier , Jofzsef Balint , Mark Kantor
IPC分类号： C07C59/147 , C07C59/00 , C07C231/00
CPC分类号： C07C235/34 , C07B2200/07 , C07C51/377 , C07C57/13 , C07C57/66 , C07C59/64 , C07C59/90
摘要： The invention relates to a process for preparing chiral octenoic acid derivatives, which constitute important intermediates in the preparation of medicament active ingredients, and also to novel intermediates which are used in the process for preparing the octenoic acid derivatives mentioned.
摘要翻译： 本发明涉及一种制备手性辛烯酸衍生物的方法，其在制备药物活性成分中构成重要的中间体，还涉及用于制备所述辛烯酸衍生物的方法中的新型中间体。
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公开(公告)号：US20090221848A1
公开(公告)日：2009-09-03
申请号：US12091795
申请日：2006-10-27
申请人： Milan Soukup , Karl Reuter , Florian Stolz , Viktor Meier , Jofzsef Balint , Mark Kantor
发明人： Milan Soukup , Karl Reuter , Florian Stolz , Viktor Meier , Jofzsef Balint , Mark Kantor
IPC分类号： C07C51/373 , C07C231/10
CPC分类号： C07C235/34 , C07B2200/07 , C07C51/377 , C07C57/13 , C07C57/66 , C07C59/64 , C07C59/90
摘要： The invention relates to a process for preparing chiral octenoic acid derivatives, which constitute important intermediates in the preparation of medicament active ingredients, and also to novel intermediates which are used in the process for preparing the octenoic acid derivatives mentioned.
摘要翻译： 本发明涉及制备手性辛烯酸衍生物的方法，其在制备药物活性成分中构成重要的中间体，还涉及用于制备所述辛烯酸衍生物的方法中的新型中间体。
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公开(公告)号：US08519162B2
公开(公告)日：2013-08-27
申请号：US12934669
申请日：2009-03-20
申请人： Karl Reuter , Viktor Meier , Florian Stolz , Dieter Krimmer , Cees Winninps
发明人： Karl Reuter , Viktor Meier , Florian Stolz , Dieter Krimmer , Cees Winninps
IPC分类号： C07D313/04
CPC分类号： C07D313/00 , C07H17/08
摘要： Described is pentamycin in a purity exceeding 95%, certain polymorphs and solvates of pentamycin, processes for their manufacture, and a method for decreasing the rate of degradation of pentamycin.
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