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1.发明申请公开(公告)号：US20170280992A1
公开(公告)日：2017-10-05
申请号：US15627077
申请日：2017-06-19
Applicant: ABBOTT MEDICAL OPTICS INC.
Inventor： Stanley W. Huth , Denise Tran
CPC classification number: A61B3/101 , A61B3/0025 , A61B3/1005 , G01B11/06 , G01J3/45
Abstract: A method for determining reflectivity of a tear film lipid layer of a patient and recommending a course of treatment based on the same. The method includes the steps of: measuring a tear film aqueous plus lipid layer relative reflectance spectrum using a wavelength-dependent optical interferometer; converting the measured tear film aqueous plus lipid layer relative reflectance spectrum to a calculated absolute reflectance spectrum; comparing the calculated absolute reflectance spectrum to a theoretical absolute lipid reflectance spectrum to determine a tear film lipid layer thickness; and determining a reflectivity value for the tear film lipid layer thickness at a first wavelength of light corresponding to ultraviolet, violet, or blue light.
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2.发明授权公开(公告)号：US09681802B2
公开(公告)日：2017-06-20
申请号：US14831678
申请日：2015-08-20
Applicant: ABBOTT MEDICAL OPTICS INC.
Inventor： Stanley W. Huth , Denise Tran
CPC classification number: A61B3/101 , A61B3/0025 , A61B3/1005 , G01B11/06 , G01J3/45
Abstract: A method for determining reflectivity of a tear film lipid layer of a patient and recommending a course of treatment based on the same. The method includes the steps of: measuring a tear film aqueous plus lipid layer relative reflectance spectrum using a wavelength-dependent optical interferometer; converting the measured tear film aqueous plus lipid layer relative reflectance spectrum to a calculated absolute reflectance spectrum; comparing the calculated absolute reflectance spectrum to a theoretical absolute lipid reflectance spectrum to determine a tear film lipid layer thickness; and determining a reflectivity value for the tear film lipid layer thickness at a first wavelength of light corresponding to ultraviolet, violet, or blue light.
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公开(公告)号：US09610011B2
公开(公告)日：2017-04-04
申请号：US15172083
申请日：2016-06-02
Applicant: ABBOTT MEDICAL OPTICS INC.
Inventor： Stanley W. Huth , Denise Tran
CPC classification number: A61B3/0025 , A61B3/1005 , A61B3/101 , A61B3/103 , G01B9/02 , G01B11/06 , G01J3/45
Abstract: A method for determining optical properties of a corneal region. The method includes the steps of obtaining a combined tear film aqueous layer plus lipid layer thickness; obtaining a tear film lipid layer thickness; subtracting the tear film lipid layer thickness from the combined tear film aqueous layer plus lipid layer thickness to obtain a tear film aqueous layer thickness; and determining a corneal layer refractive index based on the tear film lipid layer thickness and the tear film aqueous layer thickness.
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4.发明授权公开(公告)号：US09456741B2
公开(公告)日：2016-10-04
申请号：US14298036
申请日：2014-06-06
Applicant: Abbott Medical Optics Inc.
Inventor： Stan Huth , Denise Tran
CPC classification number: A61B3/0025 , A61B3/1005 , A61B3/101 , A61B3/103 , G01B9/02 , G01B11/06 , G01J3/45
Abstract: A method for determining optical properties of a corneal region. The method includes the steps of obtaining a combined tear film aqueous layer plus lipid layer thickness; obtaining a tear film lipid layer thickness; subtracting the tear film lipid layer thickness from the combined tear film aqueous layer plus lipid layer thickness to obtain a tear film aqueous layer thickness; and determining a corneal layer refractive index based on the tear film lipid layer thickness and the tear film aqueous layer thickness.
Abstract translation: 用于确定角膜区域的光学性质的方法。 该方法包括获得组合的泪膜水层加脂质层厚度的步骤; 获得泪膜脂质层厚度; 从组合的泪膜水层加脂质层厚度减去泪膜脂质层厚度，以获得泪膜水层厚度; 以及基于泪膜脂质层厚度和泪膜水层厚度确定角膜层折射率。
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5.发明申请公开(公告)号：US20150351626A1
公开(公告)日：2015-12-10
申请号：US14298036
申请日：2014-06-06
Applicant: Abbott Medical Optics Inc.
Inventor： Stan Huth , Denise Tran
CPC classification number: A61B3/0025 , A61B3/1005 , A61B3/101 , A61B3/103 , G01B9/02 , G01B11/06 , G01J3/45
Abstract: A method for determining optical properties of a corneal region. The method includes the steps of obtaining a combined tear film aqueous layer plus lipid layer thickness; obtaining a tear film lipid layer thickness; subtracting the tear film lipid layer thickness from the combined tear film aqueous layer plus lipid layer thickness to obtain a tear film aqueous layer thickness; and determining a corneal layer refractive index based on the tear film lipid layer thickness and the tear film aqueous layer thickness.
Abstract translation: 用于确定角膜区域的光学性质的方法。 该方法包括获得组合的泪膜水层加脂质层厚度的步骤; 获得泪膜脂质层厚度; 从组合的泪膜水层加脂质层厚度减去泪膜脂质层厚度，以获得泪膜水层厚度; 以及基于泪膜脂质层厚度和泪膜水层厚度确定角膜层折射率。
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Patent Agency Ranking
6.发明申请Method for Calculating Tear Film Lipid and Aqueous Layer Thicknesses and Corneal Surface Refractive Index from Interferometry Data 有权从干涉测量数据计算撕裂膜脂质和水层厚度和角膜表面折射率的方法公开(公告)号：US20140118699A1
公开(公告)日：2014-05-01
申请号：US14058564
申请日：2013-10-21
Applicant: Abbott Medical Optics Inc.
Inventor： Stanley Huth , Denise Tran , Huawei Zhao
IPC: A61B3/10
CPC classification number: A61B3/1015 , A61B3/101 , A61B3/103 , A61B3/152 , A61F2009/00872
Abstract: Disclosed herein is a method of calculating tear film lipid and aqueous layer thicknesses and/or corneal surface refractive index from interferometry data obtained from simultaneous measurements of the aqueous and lipid layers of the tear film along with a measurement of the corneal surface reflectance.
Abstract translation: 本文公开了一种从同时测量泪膜的水性和脂质层以及角膜表面反射率的测量获得的干涉测量数据计算泪膜脂质和水层厚度和/或角膜表面折射率的方法。
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7.发明申请公开(公告)号：US20170280991A1
公开(公告)日：2017-10-05
申请号：US15625815
申请日：2017-06-16
Applicant: ABBOTT MEDICAL OPTICS INC.
Inventor： Stanley W. Huth , Denise Tran
CPC classification number: A61B3/101 , A61B3/0025 , A61B3/1005 , G01B11/06 , G01J3/45
Abstract: A method for determining reflectivity of a tear film lipid layer of a patient and recommending a course of treatment based on the same. The method includes the steps of: measuring a tear film aqueous plus lipid layer relative reflectance spectrum using a wavelength-dependent optical interferometer; converting the measured tear film aqueous plus lipid layer relative reflectance spectrum to a calculated absolute reflectance spectrum; comparing the calculated absolute reflectance spectrum to a theoretical absolute lipid reflectance spectrum to determine a tear film lipid layer thickness; and determining a reflectivity value for the tear film lipid layer thickness at a first wavelength of light corresponding to ultraviolet, violet, or blue light.
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公开(公告)号：US20160345821A1
公开(公告)日：2016-12-01
申请号：US15172083
申请日：2016-06-02
Applicant: ABBOTT MEDICAL OPTICS INC.
Inventor： Stanley W. Huth , Denise Tran
CPC classification number: A61B3/0025 , A61B3/1005 , A61B3/101 , A61B3/103 , G01B9/02 , G01B11/06 , G01J3/45
Abstract: A method for determining optical properties of a corneal region. The method includes the steps of obtaining a combined tear film aqueous layer plus lipid layer thickness; obtaining a tear film lipid layer thickness; subtracting the tear film lipid layer thickness from the combined tear film aqueous layer plus lipid layer thickness to obtain a tear film aqueous layer thickness; and determining a corneal layer refractive index based on the tear film lipid layer thickness and the tear film aqueous layer thickness.
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9.发明申请FAST ABSOLUTE-REFLECTANCE METHOD FOR THE DETERMINATION OF TEAR FILM LIPID LAYER THICKNESS 有权用于确定薄膜脂肪层厚度的快速绝对反射方法公开(公告)号：US20150351628A1
公开(公告)日：2015-12-10
申请号：US14831678
申请日：2015-08-20
Applicant: ABBOTT MEDICAL OPTICS INC.
Inventor： Stanley W. Huth , Denise Tran
CPC classification number: A61B3/101 , A61B3/0025 , A61B3/1005 , G01B11/06 , G01J3/45
Abstract: A method for determining reflectivity of a tear film lipid layer of a patient and recommending a course of treatment based on the same. The method includes the steps of: measuring a tear film aqueous plus lipid layer relative reflectance spectrum using a wavelength-dependent optical interferometer; converting the measured tear film aqueous plus lipid layer relative reflectance spectrum to a calculated absolute reflectance spectrum; comparing the calculated absolute reflectance spectrum to a theoretical absolute lipid reflectance spectrum to determine a tear film lipid layer thickness; and determining a reflectivity value for the tear film lipid layer thickness at a first wavelength of light corresponding to ultraviolet, violet, or blue light.
Abstract translation: 一种用于确定患者的泪膜脂质层的反射率的方法，并且基于该方法推荐治疗过程。 该方法包括以下步骤：使用波长相关的光学干涉仪测量泪膜水相加脂质层相对反射光谱; 将测量的泪膜水相加脂质层相对反射光谱转换为计算的绝对反射光谱; 将计算的绝对反射光谱与理论绝对脂质反射光谱进行比较以确定泪膜脂质层厚度; 以及确定在对应于紫外线，紫色或蓝色光的第一波长的泪膜脂质层厚度的反射率值。
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公开(公告)号：US09132106B2
公开(公告)日：2015-09-15
申请号：US13826257
申请日：2013-03-14
Applicant: Abbott Medical Optics Inc.
Inventor： Stanley W. Huth , Denise Tran
IPC: A61K31/155 , A01N37/52 , A61L12/14
CPC classification number: A61K31/155 , A01N37/52 , A61L12/14 , A61L12/141 , A61L12/145
Abstract: Compositions and methods for disinfecting contact lenses using the compositions are disclosed. The compositions include a combination of alexidine and chlorhexidine, which surprisingly causes the composition to exhibit synergistic antimicrobial activity against Candida albicans by reducing a concentration of Candida albicans by at least 1.2 log.
Abstract translation: 公开了使用该组合物消毒隐形眼镜的组合物和方法。 组合物包括阿维膦酸和氯己定的组合，令人惊奇的是通过将白色念珠菌的浓度降低至少1.2log，使组合物对白色念珠菌显示出协同的抗微生物活性。
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