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公开(公告)号：US12252541B2
公开(公告)日：2025-03-18
申请号：US17053256
申请日：2019-06-26
Applicant: ABL BIO INC.
Inventor： Kyungjin Park , Hyejin Chung , Kyeongsu Park , Yangsoon Lee , Mikyung Chang , Jaehyoung Jeon , Youngkwang Kim , Junhyun Jeong , Jiseon Yoo , Yeunju Kim , Donghoon Yeom , Eunjung Kim , Bora Lee , Jinwon Jung
IPC: A61K39/395 , A61K47/68 , A61P35/00 , C07K16/28 , C07K16/30 , A61K39/00 , C07K14/705
Abstract: Provided are an antibody or antigen-binding fragment thereof that specifically binds to a B-cell maturation antigen (BCMA), a method of preparing the same, and use thereof. Accordingly, these can be utilized in effectively preventing or treating cancers.
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公开(公告)号：US12195538B2
公开(公告)日：2025-01-14
申请号：US17298741
申请日：2019-02-15
Applicant: ABL BIO INC. , I-MAB BIOPHARMA US LIMITED
Inventor： Eunyoung Park , Yangsoon Lee , Hyejin Chung , Eunsil Sung , Jiseon Yoo , Minji Park , Yong-Gyu Son , Hyoju Choi , Eunjung Kim , Jaeho Jung , Weon-Kyoo You , Sang Hoon Lee , Lei Fang , Wenqing Jiang
Abstract: The present disclosure provides an anti-PD-L1/anti-4-1BB bispecific antibody capable to effectively block the interactions between PD-L1 and its receptor PD-1 and between 4-1BB and its ligand. The bispecific antibody may have high binding affinity to both of a PD-L1 protein and a 4-1BB protein.
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公开(公告)号：US12240913B2
公开(公告)日：2025-03-04
申请号：US16939536
申请日：2020-07-27
Applicant: ABL Bio Inc. , YUHAN CORPORATION
Inventor： Hyejin Chung , Yeryoung Yong , Kyeongsu Park , Eunyoung Park , Ui-Jung Jung , Yangsoon Lee , Eunjung Kim , Yong-Gyu Son , Wonjun Son , Seawon Ahn , Donghoon Yeom , Chanmoo Lee , Junghyeon Hong , Moo Young Song , Eun-Jung Lee , Na Rae Lee , Young Bong Park , Eun-Jung Lee , Taewang Kim
Abstract: Provided are an anti-4-1BB/anti-HER2 bispecific antibody, and a pharmaceutical composition and a method for treating and/or preventing a cancer using the same.
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公开(公告)号：US20210024650A1
公开(公告)日：2021-01-28
申请号：US16939536
申请日：2020-07-27
Applicant: ABL Bio Inc. , YUHAN CORPORATION
Inventor： Hyejin CHUNG , Yeryoung Yong , Kyeongsu Park , Eunyoung Park , Ui-Jung Jung , Yangsoon Lee , Eunjung Kim , Yong-Gyu Son , Wonjun Son , Seawon Ahn , Donghoon Yeom , Chanmoo Lee , Junghyeon Hong , Moo Young Song , Eun-Jung Lee , Na Rae Lee , Young Bong Park , Eun-Jung Lee , Taewang Kim
Abstract: Provided are an anti-4-1BB/anti-HER2 bispecific antibody, and a pharmaceutical composition and a method for treating and/or preventing a cancer using the same.
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