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Patent Agency Ranking
公开(公告)号：US20240101687A1
公开(公告)日：2024-03-28
申请号：US18480071
申请日：2023-10-03
Applicant: ABL Bio Inc.
Inventor： Jinhyung AHN , Sungwon AN , Dongin KIM , Eunsil SUNG , Jaehyun EOM , Sang Hoon Lee , Weonkyoo YOU , Juhee KIM , Kyungjin PARK , Hyejin CHUNG , Jinwon JUNG , Bora LEE , Byungje SUNG , Yeunju KIM , Yong-Gyu SON , Seawon AHN , Daehae SONG , Jiseon YOO , Youngdon PAK , Donghoon YEOM , Yoseob LEE , Jaeho JUNG
CPC classification number: C07K16/2863 , A61K47/6845 , C07K16/18 , C07K2317/31 , C07K2317/565 , C07K2317/567
Abstract: The present invention relates to a bi-specific antibody that specifically binds to alpha-synuclein and IGF1R, and an use of the bi-specific antibody for the prevention, treatment and/or diagnosis of synucleinopathies associated with alpha-synuclein or alpha-synuclein aggregates, and can allow the alpha-synuclein antibody or an antigen-binding fragment thereof to penetrate the blood brain barrier to exert its action in the brain, and extend the half-life to maintain the efficacy for a long time.
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公开(公告)号：US20220348665A1
公开(公告)日：2022-11-03
申请号：US17616799
申请日：2020-06-15
Applicant: ABL Bio Inc.
Inventor： Sungwon AN , Jinhyung AHN , Byungje SUNG , Dongin KIM , Daehae SONG , Jaehyun EOM , Yong-Gyu SON , Kyungjin PARK , Juhee KIM , Jinwon JUNG , Bora LEE , Hyesu YUN
Abstract: The present disclosure relates to a bispecific antibody that specifically binds to alpha-synuclein and IGF1R, and an use of the bispecific antibody for the prevention, treatment and/or diagnosis of synucleinopathies associated with alpha-synuclein or alpha-synuclein aggregates, and can allow the alpha-synuclein antibody or an antigen-binding fragment thereof to penetrate the blood brain barrier to exert its action in the brain, and extend the half-life to maintain the efficacy for a long time.
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公开(公告)号：US20230227540A1
公开(公告)日：2023-07-20
申请号：US16475853
申请日：2018-01-05
Applicant: ABL Bio Inc.
Inventor： Jinhyung AHN , Sungwon AN , Dongin KIM , Eunsil SUNG , Jaehyun EOM , Sang Hoon LEE , Seung-Jae LEE , Tae Kyung KIM , Min Sun CHOI , Weonkyoo YOU , Jaeho JUNG , Juhee KIM , Jinwon JUNG , Yeunju KIM , Yonggyu SON , Byungje SUNG
CPC classification number: C07K16/18 , A61P25/14 , G01N33/6896 , A61K2039/505 , C07K2317/565
Abstract: The disclosure discloses anti α-Syn antibodies preferentially recognizing α-Syn aggregates. The antibodies of the present invention bind to α-Syn aggregates with high affinity and specificity and inhibit accumulation or intercellular transfer of α-Syn aggregates, and thus can be used for detection, diagnosis and/or treatment or prevention of various diseases caused by the accumulation of α-Syn aggregates.
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公开(公告)号：US20230357412A1
公开(公告)日：2023-11-09
申请号：US18063550
申请日：2022-12-08
Applicant: ABL BIO INC.
Inventor： Sungwon AN , Jinhyung AHN , Byungje SUNG , Dongin KIM , Daehae SONG , Jaehyun EOM , Yong-Gyu SON , Juhee KIM , Kyungjin PARK , Jinwon JUNG , Bora LEE , Hyesu YUN
CPC classification number: C07K16/2863 , A61P25/28 , C07K16/18 , A61K2039/505
Abstract: The present disclosure relates to a bispecific antibody that specifically binds to alpha-synuclein and IGF1R, and an use of the bispecific antibody for the prevention, treatment and / or diagnosis of synucleinopatheis associated with alpha-synuclein or alpha-synuclein aggregates, and can allow the alpha-synuclein antibody or an antigen-binding fragment thereof to penetrate the blood brain barrier to exert its action in the brain, and extend the half-life to maintain the efficacy for a long time.
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公开(公告)号：US20220125944A1
公开(公告)日：2022-04-28
申请号：US17436647
申请日：2020-03-06
Applicant: ABL BIO, INC.
Inventor： Jinwon JUNG , Juhee KIM , Youngdon Pak , Daehae SONG , Donghoon YEOM , Jaehyun EOM , Youngeun HONG , Bora LEE
Abstract: The present invention relates to a novel compound comprising a galactose trigger moiety and cyclopropabenzindole (CBI), and an antibody-drug conjugate prepared by using same.
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