公开(公告)号：US20240331862A1

公开(公告)日：2024-10-03

申请号：US18622407

申请日：2024-03-29

Applicant: National Taiwan University ,  National Taiwan University Hospital ,  Academia Sinica ,  National Tsing Hua University

Inventor： Shau-Ping LIN ,  Ruey-Meei WU ,  Frederick Kin Hing Phoa ,  Ming-Che KUO ,  Yi-Tzang TSAI ,  Jing-Wen HUANG ,  Yan-Han LIN ,  Hsiang-Hsuan LIN WANG ,  Chia-Lang HSU ,  Ya-Fang HSU ,  Pin-Jui KUNG

IPC: G16H50/20 ,  C12Q1/6806 ,  C12Q1/6883 ,  G01N33/68 ,  G16H10/60

CPC classification number: G16H50/20 ,  C12Q1/6806 ,  C12Q1/6883 ,  G01N33/6896 ,  G16H10/60 ,  C12Q2600/112 ,  C12Q2600/158 ,  G01N2333/4706 ,  G01N2333/521 ,  G01N2333/575 ,  G01N2333/7051 ,  G01N2333/70596 ,  G01N2333/726 ,  G01N2333/775 ,  G01N2333/82 ,  G01N2333/90203 ,  G01N2333/91057 ,  G01N2333/91091 ,  G01N2333/91215 ,  G01N2333/96419 ,  G01N2333/99 ,  G01N2800/2821 ,  G01N2800/2835

Abstract: The present invention provides a data analytic scheme for screening biomarkers for differential diagnosis of the status of Parkinson's disease, Parkinson's disease with mild cognitive impairment, Parkinson's disease dementia, Alzheimer's disease, and/or multiple system atrophy, the methodology implementing the same and the results of the screening thereof. Biomedical Oriented Logistic Dantzig Selector (BOLD Selector) was developed to identify candidate microRNAs and extracellular vesicle proteins effective at discerning between any two of the above mentioned disease categories from profiling results. The prediction models are finalized by establishing logistic regression formula for each pair of patient group differentiation.

公开(公告)号：US20230010294A1

公开(公告)日：2023-01-12

申请号：US17782595

申请日：2020-12-02

Applicant: ACADEMIA SINICA

Inventor： Wen-Chin YANG ,  Yang-Han LEE ,  Yu-Chuan LIANG ,  Frederick Kin Hing PHOA ,  Lee-Tian CHANG ,  Cheng-Chih HSU ,  Jia-Kun CHEN ,  Shau-Ping LIN ,  Chiao-LING HSIAO

IPC: A01K45/00 ,  A01K31/18 ,  A01K13/00

Abstract: A system for use in a poultry house includes a control server, a network gateway disposed in the poultry house and equipping with a wireless communication capability; a movable sensor module disposed in the poultry house, wherein the movable sensor module is movable within the poultry house for obtaining a plurality of environmental parameters associated with specific locations within the poultry house, and a sampling machine disposed in the poultry house for obtaining a sample of poultry waste on the ground of the poultry house. The movable sensor module transmits the environmental parameters to the network gateway, and the network gateway transmits the environmental parameters to the control server for processing the environmental parameters.