公开(公告)号：US20230279080A1

公开(公告)日：2023-09-07

申请号：US18146873

申请日：2022-12-27

Applicant: ACADEMIA SINICA

Inventor： Kuo-I LIN ,  Chi-Huey WONG ,  Szu-Wen WANG ,  Yi-Hsuan CHANG

IPC: C07K16/10 ,  G01N33/569 ,  A61K45/06

CPC classification number: C07K16/10 ,  A61K45/06 ,  G01N33/56983 ,  C07K2317/31 ,  C07K2317/41 ,  C07K2317/92 ,  G01N2333/165 ,  G01N2469/10

Abstract: The present disclosure relates to an antibody or antigen-binding fragment thereof that is specific for a spike protein of SARS-CoV-2. The present disclosure also relates to a pharmaceutical composition for treating and/or preventing diseases and/or disorders caused by a coronavirus in a subject in need thereof, and a method for detecting a coronavirus in a sample.

公开(公告)号：US20240228591A1

公开(公告)日：2024-07-11

申请号：US18403419

申请日：2024-01-03

Applicant: ACADEMIA SINICA

Inventor： Kuo-I LIN ,  Che MA ,  Chi-Huey WONG ,  Szu-Wen WANG ,  Yi-Hsuan CHANG ,  Xiaorui CHEN ,  Han-Yi HUANG

IPC: C07K16/10 ,  A61K39/00 ,  A61K39/42

CPC classification number: C07K16/10 ,  A61K39/42 ,  A61K2039/505 ,  C07K2317/14 ,  C07K2317/21 ,  C07K2317/24 ,  C07K2317/31 ,  C07K2317/34 ,  C07K2317/41 ,  C07K2317/565 ,  C07K2317/76 ,  C07K2317/92

Abstract: The present disclosure relates to an antibody or antigen-binding fragment thereof that specifically binds to a spike protein of SARS-COV-2. The present disclosure also relates to a pharmaceutical composition, a method for treating and/or preventing diseases and/or disorders caused by a coronavirus in a subject in need thereof, and a method for detecting a coronavirus in a sample.