公开(公告)号：US20150274771A1

公开(公告)日：2015-10-01

申请号：US14436150

申请日：2013-10-25

Applicant: AFFIBODY AB

Inventor： Per Jonasson ,  Pär Eklund

IPC: C07K1/22 ,  C07K14/00

CPC classification number: C07K1/22 ,  C07K14/00 ,  C07K14/31 ,  C07K14/315 ,  C07K2319/70

Abstract: The disclosure provides a method of separation of at least one ABD-containing molecule present in a liquid from other constituents in the liquid, comprising a step of affinity separation, in which step is used, as affinity ligand, an ABD binding polypeptide comprising an ABD binding motif BM, which motif consists of an amino acid sequence selected from EX2X3X4AX6X7EIX10X11LPNLX16X17X18QX20X21AFIX25X26LX28D (SEQ ID NO:166) and amino acid sequences with at least 89% identity thereto.

Abstract translation: 本公开提供了一种将存在于液体中的至少一种含有ABD的分子与液体中的其它成分分离的方法，其包括亲和力分离步骤，其中使用步骤作为亲和配体，包含ABD的ABD结合多肽 结合基序BM，该基序由选自EX2X3X4AX6X7EIX10X11LPNLX16X17X18QX20X21AFIX25X26LX28D（SEQ ID NO：166）的氨基酸序列和与其具有至少89％同一性的氨基酸序列组成。

公开(公告)号：US09745340B2

公开(公告)日：2017-08-29

申请号：US14436150

申请日：2013-10-25

Applicant: AFFIBODY AB

Inventor： Per Jonasson ,  Pär Eklund

IPC: C07K1/22 ,  C07K14/00 ,  C07K1/14 ,  C07K1/16 ,  C07K14/315 ,  C07K14/31

CPC classification number: C07K1/22 ,  C07K14/00 ,  C07K14/31 ,  C07K14/315 ,  C07K2319/70

Abstract: The disclosure provides a method of separation of at least one ABD-containing molecule present in a liquid from other constituents in the liquid, comprising a step of affinity separation, in which step is used, as affinity ligand, an ABD binding polypeptide comprising an ABD binding motif BM, which motif consists of an amino acid sequence selected from (SEQ ID NO: 166) EX2X3X4AX6X7EIX10X11LPNLX16X17X18QX20X21AFIX25X26LX28D and amino acid sequences with at least 89% identity thereto.

公开(公告)号：US10011641B2

公开(公告)日：2018-07-03

申请号：US14437623

申请日：2013-10-25

Applicant: AFFIBODY AB

Inventor： Per Jonasson ,  Pär Eklund

IPC: C07K14/315 ,  C07K14/195 ,  G01N33/68 ,  C07K14/00

CPC classification number: C07K14/315 ,  C07K14/00 ,  C07K14/195 ,  G01N33/68 ,  G01N33/6827

Abstract: The disclosure provides an ABD binding polypeptide comprising an ABD binding motif BM, which motif consists of an amino acid sequence selected from EX2X3X4AX6X7EIX10X11LPNLX16X17X18QX20X21AFIX25X26LX28D (SEQ ID NO: 166) and amino acid sequences with at least 89 % identity thereto.

公开(公告)号：US20150291668A1

公开(公告)日：2015-10-15

申请号：US14437623

申请日：2013-10-25

Applicant: AFFIBODY AB

Inventor： Per Jonasson ,  Pär Eklund

IPC: C07K14/315

CPC classification number: C07K14/315 ,  C07K14/00 ,  C07K14/195 ,  G01N33/68 ,  G01N33/6827

Abstract: The disclosure provides an ABD binding polypeptide comprising an ABD binding motif BM, which motif consists of an amino acid sequence selected from EX2X3X4AX6X7EIX10X11LPNLX16X17X18QX20X21AFIX25X26LX28D (SEQ ID NO:166) and amino acid sequences with at least 89% identity thereto.

Abstract translation: 本公开提供了包含ABD结合基序BM的ABD结合多肽，该基序由选自EX2X3X4AX6X7EIX10X11LPNLX16X17X18QX20X21AFIX25X26LX28D（SEQ ID NO：166）的氨基酸序列和与其具有至少89％同一性的氨基酸序列组成。