公开(公告)号：US20230256435A1

公开(公告)日：2023-08-17

申请号：US18164422

申请日：2023-02-03

Applicant: AGILENT TECHNOLOGIES, INC.

Inventor： Andrew C. Neilson ,  Jason Dell'Arciprete ,  Eric John Schultz ,  Brady Robert Paradis ,  George W. Rogers ,  Yoonseok Kam

IPC: B01L3/00

CPC classification number: B01L3/502715 ,  B01L2400/0487 ,  B01L2200/10 ,  B01L2200/147

Abstract: An analytical instrument having a sensing system, a stage adapted to receive a sample carrier, a motion actuator assembly for positioning the sensing system and/or the stage, a temperature control element, and a signal processing module are disclosed. Methods of analyzing cell samples with the analytical instrument are also disclosed.

公开(公告)号：US20240264182A1

公开(公告)日：2024-08-08

申请号：US18431441

申请日：2024-02-02

Applicant: Agilent Technologies, Inc.

Inventor： Brady Robert Paradis ,  James Niall Hynes ,  Maria Natalia Romero Filardo ,  Jason Dell'Arciprete

IPC: G01N35/00 ,  G01N27/07

CPC classification number: G01N35/00594 ,  G01N27/07

Abstract: Extended duration cell analysis is provided via a device, comprising: a chamber configured to accept: a sample carrier, that includes a plurality of wells having electrodes in electrical communication with an impedance meter; and a cartridge, including a compound and at least one delivery port for the compound; a camera configured to capture images of a cell culture in each well via associated windows in the wells when the sample carrier is positioned at a first location; a fluid handler, in communication with the sample carrier and the cartridge when the sample carrier is positioned at a second location, configured to deliver the compound from the cartridge to a given well based on an impedance measurement of a sample in the given well; and a motion stage configured to move the sample carrier between the first location and the second location.