公开(公告)号：US20210321642A1

公开(公告)日：2021-10-21

申请号：US17362460

申请日：2021-06-29

Applicant: AJINOMOTO CO., INC.

Inventor： Susumu SHIBAHARA ,  Sachiko YONEMARU ,  Koji HAGA ,  Yuki MIYAZAWA ,  Takaaki SATO

IPC: A23K50/10 ,  A23K40/30 ,  A23K20/142 ,  A23K20/174 ,  A23K20/158 ,  A23K10/20 ,  A23K10/30

Abstract: Feed additive compositions for ruminants containing (A) at least one member selected from the group consisting of hydrogenated vegetable oil and hydrogenated animal oil each having a melting point of higher than 50° C. and lower than 90° C.; (B) not less than 0.05 wt % and not more than 6 wt % of lecithin; (C) not less than 30 wt % and less than 65 wt % of a biologically active substance; (D) not less than 0.01 wt % and less than 0.8 wt % of a natural vegetable oil; and not less than 0.1 wt % and less than 6 wt % of water exhibit high protection in the rumen and are also superior in dissolution in the lower gastrointestinal tract.

公开(公告)号：US20190246665A1

公开(公告)日：2019-08-15

申请号：US16394548

申请日：2019-04-25

Applicant: AJINOMOTO CO., INC.

Inventor： Susumu SHIBAHARA ,  Sachiko YONEMARU ,  Koji HAGA ,  Yuki MIYAZAWA ,  Takaaki SATO

IPC: A23K50/10 ,  A23K40/30 ,  A23K20/158 ,  A23K20/142 ,  A23K20/174

CPC classification number: A23K50/10 ,  A23K10/20 ,  A23K10/30 ,  A23K20/142 ,  A23K20/158 ,  A23K20/174 ,  A23K40/30

Abstract: Feed additive compositions for ruminants containing (A) at least one selected from hydrogenated vegetable oil and hydrogenated animal oil each having a melting point of higher than 50° C. and lower than 90° C., (B) lecithin, (C) a biologically active substance, (D) a natural vegetable oil, and water, wherein when a scattering profile is measured after maintaining at 40° C. for 15 min, and then measured by further maintaining at 40° C. for 30 min by a small-angle and wide-angle x-ray scattering method, a peak having the maximum peak intensity in a region where the scattering angle 2θ is not more than 5° has a ratio (t/s) of 0.9-1.1 wherein s is peak intensity when maintained at 40° C. for 15 min and t is peak intensity when maintained at 40° C. for 45 min, and a peak having the maximum peak intensity in a region where the scattering angle 2θ is 17°-23° has a ratio (y/x) of 0.7-0.9 wherein x is peak intensity when maintained at 40° C. for 15 min and y is peak intensity when maintained at 40° C. for 45 min, have high protection in the rumen and are also superior in dissolution in the gastrointestinal tract.

公开(公告)号：US20190204332A1

公开(公告)日：2019-07-04

申请号：US16233032

申请日：2018-12-26

Applicant: AJINOMOTO CO., INC.

Inventor： Takashi MIKAMI ,  Akira IMAIZUMI ,  Takayuki TANAKA ,  Yuki MIYAZAWA ,  Mina NAKAMURA ,  Kazuki NAKAGAWA ,  Takeshi FUJIEDA

IPC: G01N33/68 ,  G01N33/92 ,  G01N33/66 ,  G01N33/62

CPC classification number: G01N33/68 ,  G01N33/62 ,  G01N33/66 ,  G01N33/92

Abstract: An evaluating method includes an evaluating step of evaluating a state of ketosis in postpartum dairy cows for a dairy cow using at least one value of concentration values of Ala, Arg, Asn, Asp, BCAA, Cit, Cys, Glu, Gln, Gly, His, Ile, Leu, Lys, Met, 3MeHis, Orn, Phe, Pro, Ser, Tau, Thr, Trp, Tyr, and Val and concentration values of ALB, ALT, AST, BHBA, BUN, Ca, gGTP, Glc, NEFA, T−Bil, TCHO, TG, and TP in blood of the dairy cow before parturition.

公开(公告)号：US20140308412A1

公开(公告)日：2014-10-16

申请号：US14316827

申请日：2014-06-27

Applicant: AJINOMOTO CO., INC.

Inventor： Hidetsugu NAKAZAWA ,  Hiroyuki SATO ,  Yuki MIYAZAWA ,  Susumu SHIBAHARA ,  Sachiko OKA ,  Yumi GOTO

IPC: A23K1/16 ,  A23K1/18

CPC classification number: A23K1/1634 ,  A23K20/142 ,  A23K20/158 ,  A23K40/35 ,  A23K50/10

Abstract: A feed additive composition includes a protective agent, lecithin in an amount of 0.05 to 6% by weight relative to a total weight of the composition, a basic amino acid in an amount of at least 40% by weight and less than 65% by weight relative to the total weight of the composition, and water. A method of producing a feed additive composition includes preparing a molten mixture of at least one protective agent, lecithin and at least one basic amino acid, and solidifying the molten mixture by immersing the molten mixture in water or an aqueous liquid. The protective agent includes hydrogenated vegetable oils and/or hydrogenated animal oils having melting points of greater than 50° C. and less than 90° C.

Abstract translation: 饲料添加剂组合物包含相对于组合物总重量为0.05至6重量％的保护剂卵磷脂，至少40重量％且小于65重量％的碱性氨基酸 相对于组合物的总重量和水。 制备饲料添加剂组合物的方法包括制备至少一种保护剂，卵磷脂和至少一种碱性氨基酸的熔融混合物，并将熔融混合物浸入水或含水液体中来固化熔融混合物。 保护剂包括熔点大于50℃且小于90℃的氢化植物油和/或氢化动物油。

公开(公告)号：US20230138420A1

公开(公告)日：2023-05-04

申请号：US18147860

申请日：2022-12-29

Applicant: AJINOMOTO CO., INC.

Inventor： Sachiko YONEMARU ,  Koji HAGA ,  Yuki MIYAZAWA ,  Susumu SHIBAHARA

IPC: A23K20/142 ,  A23K20/158 ,  A23K20/174 ,  A23K40/35 ,  A23K50/10 ,  A61K31/198 ,  A61K31/405 ,  A61K31/455 ,  A61K31/519 ,  A61K31/714

Abstract: Dispersion type feed additive compositions for ruminants, containing (A) at least one selected from hydrogenated vegetable oil and hydrogenated animal oil each having a melting point of higher than 50° C. and lower than 90° C., (B) not less than 0.01 wt % and not more than 6 wt % of a surfactant, (C) not less than 16 wt % and not more than 72 wt % of a biologically active substance (excluding L-lysine and a salt thereof), and (D) not less than 1 wt % and not more than 40 wt % of L-lysine or a salt thereof, contain a biologically active substance at a high concentration, show high protection in the rumen, and are also superior in dissolution in the intestinal tract.

公开(公告)号：US20210172958A1

公开(公告)日：2021-06-10

申请号：US17178805

申请日：2021-02-18

Applicant: AJINOMOTO CO., INC.

Inventor： Takashi MIKAMI ,  Akira IMAIZUMI ,  Takayuki TANAKA ,  Yuki MIYAZAWA ,  Mina NAKAMURA ,  Kazuki NAKAGAWA ,  Takeshi FUJIEDA

IPC: G01N33/68 ,  G01N33/62 ,  G01N33/66 ,  G01N33/92

Abstract: An evaluating method includes an evaluating step of evaluating a state of ketosis in postpartum dairy cows for a dairy cow using at least one value of concentration values of Ala, Arg, Asn, Asp, BCAA, Cit, Cys, Glu, Gln, Gly, His, Ile, Leu, Lys, Met, 3MeHis, Orn, Phe, Pro, Ser, Tau, Thr, Trp, Tyr, and Val and concentration values of ALB, ALT, AST, BHBA, BUN, Ca, gGTP, Glc, NEFA, T-Bil, TCHO, TG, and TP in blood of the dairy cow before parturition.

公开(公告)号：US20210007371A1

公开(公告)日：2021-01-14

申请号：US17034905

申请日：2020-09-28

Applicant: AJINOMOTO CO., INC.

Inventor： Sachiko YONEMARU ,  Koji HAGA ,  Yuki MIYAZAWA ,  Susumu SHIBAHARA

IPC: A23K20/142 ,  A23K20/158 ,  A23K20/174 ,  A23K40/35 ,  A23K50/10 ,  A61K31/198 ,  A61K31/519 ,  A61K31/714 ,  A61K31/455 ,  A61K31/405

Abstract: Dispersion type feed additive compositions for ruminants, containing (A) at least one selected from hydrogenated vegetable oil and hydrogenated animal oil each having a melting point of higher than 50° C. and lower than 90° C., (B) not less than 0.01 wt % and not more than 6 wt % of a surfactant, (C) not less than 16 wt % and not more than 72 wt % of a biologically active substance (excluding L-lysine and a salt thereof), and (D) not less than 1 wt % and not more than 40 wt % of L-lysine or a salt thereof, contain a biologically active substance at a high concentration, show high protection in the rumen, and are also superior in dissolution in the intestinal tract.

公开(公告)号：US20190246666A1

公开(公告)日：2019-08-15

申请号：US16394594

申请日：2019-04-25

Applicant: AJINOMOTO CO., INC.

Inventor： Susumu SHIBAHARA ,  Sachiko YONEMARU ,  Koji HAGA ,  Yuki MIYAZAWA ,  Takaaki SATO

IPC: A23K50/10 ,  A23K40/30 ,  A23K20/158 ,  A23K20/174 ,  A23K20/142

CPC classification number: A23K50/10 ,  A23K10/20 ,  A23K10/30 ,  A23K20/142 ,  A23K20/158 ,  A23K20/174 ,  A23K40/30

Abstract: Feed additive compositions for ruminants containing (A) at least one member selected from the group consisting of hydrogenated vegetable oil and hydrogenated animal oil each having a melting point of higher than 50° C. and lower than 90° C.; (B) not less than 0.05 wt % and not more than 6 wt % of lecithin; (C) not less than 30 wt % and less than 65 wt % of a biologically active substance; (D) not less than 0.01 wt % and less than 0.8 wt % of a natural vegetable oil; and not less than 0.1 wt % and less than 6 wt % of water exhibit high protection in the rumen and are also superior in dissolution in the lower gastrointestinal tract.

公开(公告)号：US20140065260A1

公开(公告)日：2014-03-06

申请号：US14075099

申请日：2013-11-08

Applicant: AJINOMOTO CO., INC.

Inventor： Hidetsugu NAKAZAWA ,  Hiroyuki SATO ,  Yuki MIYAZAWA ,  Susumu SHIBAHARA ,  Sachiko OKA ,  Yumi GOTO

IPC: A23K1/16

Abstract: A feed additive composition includes a protective agent, lecithin, an acidic or neutral amino acid, and water. A method of producing a feed additive composition includes preparing a molten mixture of a protective agent, lecithin, and an acidic or neutral amino acid, and immersing the molten mixture in water or an aqueous liquid to obtain a solidified mixture. Feed additives may be obtained by such method. The protective agent may include a hydrogenated vegetable oil or hydrogenated animal oil having a melting point of higher than 50° C. and lower than 90° C.

Abstract translation: 饲料添加剂组合物包括保护剂，卵磷脂，酸性或中性氨基酸和水。 制备饲料添加剂组合物的方法包括制备保护剂，卵磷脂和酸性或中性氨基酸的熔融混合物，并将熔融混合物浸入水或含水液体中以获得固化的混合物。 饲料添加剂可以通过这种方法获得。 保护剂可以包括熔点高于50℃且低于90℃的氢化植物油或氢化动物油。