公开(公告)号：US12171870B2

公开(公告)日：2024-12-24

申请号：US17392425

申请日：2021-08-03

Applicant: ALCON INC.

Inventor： Jing Cheng ,  Stephen Raymond Perreault ,  Daqing Wu ,  Steve Yun Zhang ,  Jang-Shing Chiou

IPC: A61K9/00 ,  A45C11/00 ,  A61K9/51 ,  A61K31/685 ,  A61L12/04 ,  B65B25/00

Abstract: The present invention relates to a method to load a water insoluble phospholipid as nanoparticles to load into a hydrogel contact lens in autoclaving process during the hydrogel contact lens manufacturing process without an extra manufacturing step and without swelling the hydrogel contact lens with an organic solvent. The phospholipid nanoparticles loaded in hydrogel contact lens subsequently releases to the eye upon wearing.

公开(公告)号：US12171871B2

公开(公告)日：2024-12-24

申请号：US17392448

申请日：2021-08-03

Applicant: ALCON INC.

Inventor： Junhao Ge ,  Steve Yun Zhang ,  Daqing Wu ,  Jing Cheng ,  Yuan Chang ,  Feng Jing ,  Jang-Shing Chiou ,  Stephen Raymond Perreault

IPC: A61K9/00 ,  A45C11/00 ,  A61K9/51 ,  A61K31/685 ,  A61L12/04 ,  B65B25/00

Abstract: The present invention relates to a method to load a water insoluble phospholipid as nanoparticles to load into a hydrogel contact lens in autoclaving process during the hydrogel contact lens manufacturing process without an extra manufacturing step and without swelling the hydrogel contact lens with an organic solvent. The phospholipid nanoparticles loaded in hydrogel contact lens subsequently releases to the eye upon wearing.