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公开(公告)号：US12171870B2
公开(公告)日：2024-12-24
申请号：US17392425
申请日：2021-08-03
Applicant: ALCON INC.
Inventor： Jing Cheng , Stephen Raymond Perreault , Daqing Wu , Steve Yun Zhang , Jang-Shing Chiou
Abstract: The present invention relates to a method to load a water insoluble phospholipid as nanoparticles to load into a hydrogel contact lens in autoclaving process during the hydrogel contact lens manufacturing process without an extra manufacturing step and without swelling the hydrogel contact lens with an organic solvent. The phospholipid nanoparticles loaded in hydrogel contact lens subsequently releases to the eye upon wearing.
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公开(公告)号：US20210302625A1
公开(公告)日：2021-09-30
申请号：US17205169
申请日：2021-03-18
Applicant: Alcon Inc.
Inventor： Jing Cheng , Wei Liang , Steve Yun Zhang
Abstract: The invention is generally related to an insert for being embedded in a silicone hydrogel contact lens. The insert is made of a crosslinked materials which are rigid in dry state at room temperature (from about 22° C. to about 26° C.), have a high oxygen permeability and a high refractive index in fully hydrated state, and can become softer at a temperature great than 32° C. Such materials are useful for making inserts in embedded contact lenses for correcting corneal astigmatism, presbyopia, and color blindness lenses and for imparting photochromic characteristics to the lenses. The invention is also related to a method for making embedded silicone hydrogel contact lenses comprising an insert of the invention therein and to embedded silicone hydrogel contact lenses comprising an insert of the invention therein.
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公开(公告)号：US20230382065A1
公开(公告)日：2023-11-30
申请号：US18322651
申请日：2023-05-24
Applicant: Alcon Inc.
Inventor： Jing Cheng , Michelle Plavnik , Ya-Wen Chang , Feng Jing , Steve Yun Zhang
IPC: B29D11/00
CPC classification number: B29D11/00134 , B29D11/00442 , B29D11/0048
Abstract: A method for producing embedded hydrogel contact lenses comprises at least the following steps: obtaining an insert made of a crosslinked polymeric material comprising repeating units of a free-radical photoinitiator; placing the insert in a female lens mold half; dosing an amount of a lens-forming composition to immerse the insert in the female lens mold half; closing tightly a male lens mold half onto the top of the female lens mold half halves to form a molding assembly; actinically curing both the lens-forming composition in the molding assembly to form an embedded hydrogel lens precursor which comprises a bulk hydrogel material formed the lens-forming composition and the insert that is embedded therein and covalently linked to the bulk hydrogel material.
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公开(公告)号：US11618823B2
公开(公告)日：2023-04-04
申请号：US17205186
申请日：2021-03-18
Applicant: Alcon Inc.
Inventor： Jing Cheng , Steve Yun Zhang
IPC: C08L83/06 , C08F220/12 , C08G77/442 , C08G77/20 , G02B1/04
Abstract: The invention is generally related to an insert for being embedded in a silicone hydrogel contact lens. The insert is made of a crosslinked materials which are rigid in dry state at room temperature (from about 22° C. to about 26° C.), have a high oxygen permeability and a high refractive index in fully hydrated state. Such materials are useful for making inserts in embedded contact lenses for correcting corneal astigmatism, presbyopia, and color blindness lenses and for imparting photochromic characteristics to the lenses. The invention is also related to a method for making embedded silicone hydrogel contact lenses comprising an insert of the invention therein and to embedded silicone hydrogel contact lenses comprising an insert of the invention therein.
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公开(公告)号：US12171871B2
公开(公告)日：2024-12-24
申请号：US17392448
申请日：2021-08-03
Applicant: ALCON INC.
Inventor： Junhao Ge , Steve Yun Zhang , Daqing Wu , Jing Cheng , Yuan Chang , Feng Jing , Jang-Shing Chiou , Stephen Raymond Perreault
Abstract: The present invention relates to a method to load a water insoluble phospholipid as nanoparticles to load into a hydrogel contact lens in autoclaving process during the hydrogel contact lens manufacturing process without an extra manufacturing step and without swelling the hydrogel contact lens with an organic solvent. The phospholipid nanoparticles loaded in hydrogel contact lens subsequently releases to the eye upon wearing.
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Patent Agency Ranking
公开(公告)号：US20230339149A1
公开(公告)日：2023-10-26
申请号：US18306637
申请日：2023-04-25
Applicant: Alcon Inc.
Inventor： Jing Cheng , Feng Jing , Steve Yun Zhang
CPC classification number: B29C39/026 , B29C39/006 , B29C39/021 , B29C39/26 , B29C39/36 , G02B1/043 , B29K2101/10
Abstract: A method for producing embedded hydrogel contact lenses comprises at least the following steps: obtaining an insert made of a crosslinked polymeric material comprising iniferter moieties covalently attached thereto; placing the insert in a female lens mold half; dosing an amount of a lens-forming composition to immerse the insert in the female lens mold half; closing tightly a male lens mold half onto the top of the female lens mold half halves to form a molding assembly; curing the lens-forming composition in the molding assembly to form an embedded hydrogel lens precursor which comprises a bulk hydrogel material formed the lens-forming composition and the insert that is embedded therein and covalently linked to the bulk hydrogel material.
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公开(公告)号：US20220326412A1
公开(公告)日：2022-10-13
申请号：US17710224
申请日：2022-03-31
Applicant: Alcon Inc.
Inventor： Yuan Chang , Junhao Ge , Ying Pi , Cornelius Daniel Niculas , Yang Zheng , Steve Yun Zhang , Michelle Plavnik , Ethan Leveillee , Jing Cheng , Augustine Twum Kumi
IPC: G02B1/04 , C08G77/442 , B29D11/00 , G02C7/04
Abstract: The invention is directed to an embedded hydrogel contact lens, which comprises an insert sandwiched between two layers of hydrogel materials and can be produced according to a cast molding method including the procedures involving two females halves (FC1 and FC2) and two male halves (BC1 and BC2) and three consequential molding steps involving three molding assemblies: the 1st one formed between FC1 and BC1 for molding an insert; the 2nd one formed between FC1 and BC2 for molding a lens precursor having the molded insert embedded in a layer of a hydrogel material in a way that the front surface of the molded insert merges with the convex surface of the lens precursor; and the 3rd one formed between FC2 and BC2 for molding an embedded hydrogel contact of the invention.
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公开(公告)号：US20210347929A1
公开(公告)日：2021-11-11
申请号：US17313459
申请日：2021-05-06
Applicant: Alcon Inc.
Inventor： Jing Cheng , Yang Zheng , Steve Yun Zhang , Lindsay Olson
IPC: C08F283/12 , C08J3/075
Abstract: The invention provides a contact lens manufacturing method comprising a process for removing unprocessed molded silicone hydrogel contact lenses from mold halves in a relatively efficient and consistent manner. The method of the invention involves using a silicone fluid (or so-called silicone oil) as non-reactive diluent in SiHy lens formulation for making SiHy contact lenses. Resultant SiHy contact lenses cast-molded from such a SiHy lens formulation can have a significantly reduced adhesion force with the molding surfaces of a lens mold and consequently a higher efficiency and consistency in removing unprocessed molded SiHy contact lenses from mold halves can be achieved. This method of the invention can be easily implemented in a production environment for enhancing the production yield.
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公开(公告)号：US20210292557A1
公开(公告)日：2021-09-23
申请号：US17205186
申请日：2021-03-18
Applicant: Alcon Inc.
Inventor： Jing Cheng , Steve Yun Zhang
Abstract: The invention is generally related to an insert for being embedded in a silicone hydrogel contact lens. The insert is made of a crosslinked materials which are rigid in dry state at room temperature (from about 22° C. to about 26° C.), have a high oxygen permeability and a high refractive index in fully hydrated state. Such materials are useful for making inserts in embedded contact lenses for correcting corneal astigmatism, presbyopia, and color blindness lenses and for imparting photochromic characteristics to the lenses. The invention is also related to a method for making embedded silicone hydrogel contact lenses comprising an insert of the invention therein and to embedded silicone hydrogel contact lenses comprising an insert of the invention therein.
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公开(公告)号：US12194699B2
公开(公告)日：2025-01-14
申请号：US17710199
申请日：2022-03-31
Applicant: Alcon Inc.
Inventor： Zahra Bassampour , Chandana Kolluru , Steve Yun Zhang , Junhao Ge , Yang Zheng , Cornelius Daniel Niculas , David Andrew Icenogle , Jing Cheng , Yuan Chang , Augustine Twum Kumi , Michelle Plavnik
Abstract: The invention relates to a method for producing embedded hydrogel contact lenses involving a set of 3-mold halves consisting essentially of: one female lens mold half having a molding surface defining the anterior surface of a contact lens; one male lens mold half having a molding surface defining the posterior surface of the contact lens; and an insert mold half having a molding surface defining one of the front and back surfaces of an insert. One of the lens mold halves is used twice: first with the insert mold half for molding an insert during first curing process and then with the other lens mold half for molding an embedded hydrogel contact lens with the molded insert embedded partially or fully therein during second curing process. The invention also relates to embedded hydrogel contact lenses produced from a method of the invention.
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