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公开(公告)号：US20210017275A1
公开(公告)日：2021-01-21
申请号：US16614302
申请日：2018-05-15
Applicant: Alector LLC
Inventor： Kate MONROE , Helen LAM , Patricia CULP , Arnon ROSENTHAL
Abstract: The present disclosure is generally directed to compositions that include antibodies, e.g., monoclonal, chimeric, humanized antibodies, antibody fragments, etc., that specifically bind on or more epitopes within a Siglec-5 protein, e.g., human Siglec-5 or a mammalian Siglec-5, and use of such compositions in preventing, reducing risk, or treating an individual in need thereof.
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公开(公告)号：US20190002560A1
公开(公告)日：2019-01-03
申请号：US15735947
申请日：2016-06-11
Applicant: ALECTOR LLC
Inventor： Kate MONROE , Helen LAM , Francesca AVOGADRI-CONNORS , Seung-Joo LEE , William MONTEITH , Herve RHINN , Arnon ROSENTHAL
IPC: C07K16/28 , A61K39/395 , A61P35/00 , C12N15/85
Abstract: The present disclosure is generally directed to compositions that include antibodies, e.g., monoclonal, chimeric, humanized antibodies, antibody fragments, etc., that specifically bind one or more epitopes within a CD33 protein, e.g., human CD33 or a mammalian CD33, and use of such compositions in preventing, reducing risk, or treating an individual in need thereof.
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公开(公告)号：US20220315656A1
公开(公告)日：2022-10-06
申请号：US17740100
申请日：2022-05-09
Applicant: Alector LLC
Inventor： Kate MONROE , Helen LAM , Patricia CULP , Arnon ROSENTHAL
Abstract: The present disclosure is generally directed to compositions that include antibodies, e.g., monoclonal, chimeric, humanized antibodies, antibody fragments, etc., that specifically bind on or more epitopes within a Siglec-5 protein, e.g., human Siglec-5 or a mammalian Siglec-5, and use of such compositions in preventing, reducing risk, or treating an individual in need thereof.
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公开(公告)号：US20190010230A1
公开(公告)日：2019-01-10
申请号：US16138761
申请日：2018-09-21
Applicant: Alector LLC
Inventor： Kate MONROE , Tina SCHWABE , Francesca AVOGADRI-CONNORS , Ilaria TASSI , Helen LAM , Arnon ROSENTHAL
Abstract: The invention is generally directed to methods and compositions that include antibodies, e.g., monoclonal, chimeric, humanized antibodies, antibody fragments, etc., that specifically bind a TREM2 protein, e.g., a mammalian TREM2 and/or human TREM2. The methods provided herein find use in preventing, reducing risk, or treating an individual having dementia, frontotemporal dementia, Alzheimer's disease, Nasu-Hakola disease, or multiple sclerosis.
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公开(公告)号：US20170240631A1
公开(公告)日：2017-08-24
申请号：US15502766
申请日：2015-08-08
Applicant: ALECTOR LLC
Inventor： Kate MONROE , Tina SCHWABE , Francesca AVOGADRI-CONNORS , IIaria TASSI , Helen LAM , Arnon ROSENTHAL
IPC: C07K16/28
CPC classification number: C07K16/2803 , A61K2039/505 , C07K16/28 , C07K16/283 , C07K2317/21 , C07K2317/31 , C07K2317/33 , C07K2317/34 , C07K2317/52 , C07K2317/55 , C07K2317/56 , C07K2317/75 , C07K2317/76 , C07K2317/92
Abstract: The invention is generally directed to methods and compositions that include antibodies, e.g., monoclonal, chimeric, humanized antibodies, antibody fragments, etc., that specifically bind a TREM2 protein, e.g., a mammalian TREM2 and/or human TREM2. The methods provided herein find use in preventing, reducing risk, or treating an individual having dementia, frontotemporal dementia, Alzheimer's disease, Nasu-Hakola disease, or multiple sclerosis.
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Patent Agency Ranking
公开(公告)号：US20220411503A1
公开(公告)日：2022-12-29
申请号：US17831336
申请日：2022-06-02
Applicant: Alector LLC
Inventor： Kate MONROE , Helen LAM , Arnon ROSENTHAL , Seung-Joo LEE , Francesca AVOGADRI-CONNORS , William MONTEITH
IPC: C07K16/28 , A61K39/395 , A61K45/06
Abstract: The present disclosure is generally directed to compositions that include antibodies, e.g., monoclonal, chimeric, humanized antibodies, antibody fragments, etc., that specifically bind on or more epitopes within a Siglec-7 protein, e.g., human Siglec-7 or a mammalian Siglec-7, and use of such compositions in preventing, reducing risk, or treating an individual in need thereof.
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公开(公告)号：US20220281976A1
公开(公告)日：2022-09-08
申请号：US17752606
申请日：2022-05-24
Applicant: Alector LLC
Inventor： Arnon ROSENTHAL , Kate MONROE , Francesca AVOGADRI-CONNORS
Abstract: The present disclosure is generally directed to compositions that include antibodies, e.g., monoclonal, chimeric, humanized antibodies, antibody fragments, etc., that specifically bind on or more epitopes within a CD33 protein, e.g., human CD33 or a mammalian CD33, and use of such compositions in preventing, reducing risk, or treating an individual in need thereof.
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公开(公告)号：US20190062427A1
公开(公告)日：2019-02-28
申请号：US15772010
申请日：2016-10-28
Applicant: ALECTOR LLC
Inventor： Arnon ROSENTHAL , Kate MONROE , Seung-Joo LEE
Abstract: The present disclosure is generally directed to compositions that include antibodies, e.g., monoclonal, chimeric, humanized antibodies, antibody fragments, etc., that specifically bind one or more epitopes within a Siglec-9 protein, e.g., human Siglec-9 or a mammalian Siglec-9, and use of such compositions in preventing, reducing risk, or treating an individual in need thereof.
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公开(公告)号：US20220251190A1
公开(公告)日：2022-08-11
申请号：US17459835
申请日：2021-08-27
Applicant: Alector LLC
Inventor： Kate MONROE , Helen LAM , Francesca AVOGADRI-CONNORS , Seung-Joo LEE , William MONTEITH , Herve RHINN , Arnon ROSENTHAL
IPC: C07K16/28 , A61P35/00 , A61K39/395 , C12N15/85
Abstract: The present disclosure is generally directed to compositions that include antibodies, e.g., monoclonal, chimeric, humanized antibodies, antibody fragments, etc., that specifically bind on or more epitopes within a CD33 protein, e.g., human CD33 or a mammalian CD33, and use of such compositions in preventing, reducing risk, or treating an individual in need thereof.
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公开(公告)号：US20200277374A1
公开(公告)日：2020-09-03
申请号：US16792040
申请日：2020-02-14
Applicant: Alector LLC
Inventor： Kate MONROE , Helen LAM , Arnon ROSENTHAL , Seung-Joo LEE , Francesca AVOGADRI-CONNORS , William MONTEITH
IPC: C07K16/28 , A61K39/395 , A61K45/06
Abstract: The present disclosure is generally directed to compositions that include antibodies, e.g., monoclonal, chimeric, humanized antibodies, antibody fragments, etc., that specifically bind on or more epitopes within a Siglec-7 protein, e.g., human Siglec-7 or a mammalian Siglec-7, and use of such compositions in preventing, reducing risk, or treating an individual in need thereof.
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