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公开(公告)号:US20240174746A1
公开(公告)日:2024-05-30
申请号:US18551162
申请日:2022-03-17
Applicant: ALECTOR LLC
Inventor: Eric BROWN , Angie Grace YEE , Tina SCHWABE , Herve RHINN , Arnon ROSENTHAL
CPC classification number: C07K16/28 , A61K2039/505 , C07K2317/33 , C07K2317/56 , C07K2317/76
Abstract: The present disclosure is generally directed to compositions that include antibodies, e.g., monoclonal antibodies, antibody fragments, etc., that specifically bind a TMEM106B polypeptide, e.g., a mammalian TMEM106B or human TMEM106B, and use of such compositions in preventing, reducing risk, or treating an individual in need thereof.
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公开(公告)号:US20190002560A1
公开(公告)日:2019-01-03
申请号:US15735947
申请日:2016-06-11
Applicant: ALECTOR LLC
Inventor: Kate MONROE , Helen LAM , Francesca AVOGADRI-CONNORS , Seung-Joo LEE , William MONTEITH , Herve RHINN , Arnon ROSENTHAL
IPC: C07K16/28 , A61K39/395 , A61P35/00 , C12N15/85
Abstract: The present disclosure is generally directed to compositions that include antibodies, e.g., monoclonal, chimeric, humanized antibodies, antibody fragments, etc., that specifically bind one or more epitopes within a CD33 protein, e.g., human CD33 or a mammalian CD33, and use of such compositions in preventing, reducing risk, or treating an individual in need thereof.
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公开(公告)号:US20240166738A1
公开(公告)日:2024-05-23
申请号:US18551963
申请日:2022-03-23
Applicant: ALECTOR LLC
Inventor: Herve RHINN , Eric BROWN
Abstract: The present disclosure is generally directed to uses of antibodies that bind to a TMEM106B protein in treating, preventing, or reducing the risk of coronavirus (e.g., SARS-COV-2) infection.
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公开(公告)号:US20240076362A1
公开(公告)日:2024-03-07
申请号:US18310207
申请日:2023-05-01
Applicant: Alector LLC
Inventor: Jeonghoon SUN , Wei-Hsien HO , Muhammad A. ALHAWAGRI , Philip Ling KONG , Herve RHINN , Hua LONG , Karpagam SRINIVASAN , Ananya MITRA , Daniel P. BERMINGHAM , Klaus-Dieter HEGER , Santiago Viveros SALAZAR , Francesca CIGNARELLA , Ilaria TASSI , Tina SCHWABE , Angie Grace YEE , Arnon ROSENTHAL
IPC: C07K16/18
CPC classification number: C07K16/18 , A61K2039/505
Abstract: The present disclosure is generally directed to compositions that include antibodies, e.g., monoclonal antibodies, humanized antibodies and antibody fragments, that specifically bind a MS4A4A polypeptide, e.g., a mammalian MS4A4A or human MS4A4A, and use of such compositions in preventing, reducing risk, or treating an individual in need thereof.
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公开(公告)号:US20220380455A1
公开(公告)日:2022-12-01
申请号:US17722624
申请日:2022-04-18
Applicant: Alector LLC
Inventor: Philip KONG , Herve RHINN , Tina SCHWABE , Angie YEE , Arnon ROSENTHAL
Abstract: The present disclosure is generally directed to compositions that include antibodies, e.g., monoclonal, antibodies, anti-body fragments, etc., that specifically bind a MS4A6A polypeptide, e g., a mammalian MS4A6A or human MS4A6A, and use of such compositions in preventing, reducing risk, or treating an individual in need thereof.
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公开(公告)号:US20240329054A1
公开(公告)日:2024-10-03
申请号:US18656427
申请日:2024-05-06
Applicant: Alector LLC
Inventor: Robert PAUL , Michael F. WARD , Felix Leejia YEH , Yijie LIAO , Herve RHINN , Arnon ROSENTHAL
IPC: G01N33/68
CPC classification number: G01N33/6854 , G01N33/6896 , G01N2333/70503 , G01N2800/2821 , G01N2800/52
Abstract: The present disclosure relates generally to biomarkers of activity and/or therapeutic efficacy of anti-CD33 antibodies for the treatment of a disease or injury in an individual, as well as methods related thereto.
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公开(公告)号:US20230126400A1
公开(公告)日:2023-04-27
申请号:US17821006
申请日:2022-08-19
Applicant: Alector LLC
Inventor: Philip KONG , Herve RHINN , Tina SCHWABE , Angie YEE , Ilaria TASSI , Muhammad Abbas ALHAWAGRI , Arnon ROSENTHAL
IPC: C07K16/28
Abstract: The present disclosure is generally directed to compositions that include antibodies, e.g., monoclonal, antibodies, antibody fragments, etc.. that specifically bind a MS4A4A polypeptide, e.g., a mammalian MS4A4A or human MS4A4A, and use of such compositions in preventing, reducing risk, or treating an individual in need thereof.
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公开(公告)号:US20220251190A1
公开(公告)日:2022-08-11
申请号:US17459835
申请日:2021-08-27
Applicant: Alector LLC
Inventor: Kate MONROE , Helen LAM , Francesca AVOGADRI-CONNORS , Seung-Joo LEE , William MONTEITH , Herve RHINN , Arnon ROSENTHAL
IPC: C07K16/28 , A61P35/00 , A61K39/395 , C12N15/85
Abstract: The present disclosure is generally directed to compositions that include antibodies, e.g., monoclonal, chimeric, humanized antibodies, antibody fragments, etc., that specifically bind on or more epitopes within a CD33 protein, e.g., human CD33 or a mammalian CD33, and use of such compositions in preventing, reducing risk, or treating an individual in need thereof.
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公开(公告)号:US20200339680A1
公开(公告)日:2020-10-29
申请号:US16959081
申请日:2018-12-21
Applicant: ALECTOR LLC
Inventor: Arnon ROSENTHAL , Eric BROWN , Tina SCHWABE , Angie YEE , Herve RHINN
IPC: C07K16/28
Abstract: The present disclosure is generally directed to compositions that include antibodies, e.g., monoclonal antibodies, antibody fragments, etc., that specifically bind a TMEM106B polypeptide, e.g., a mammalian TMEM106B or human TMEM106B, and use of such compositions in preventing, reducing risk, or treating an individual in need thereof.
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公开(公告)号:US20230303681A1
公开(公告)日:2023-09-28
申请号:US17820686
申请日:2022-08-18
Applicant: ALECTOR LLC
Inventor: Arnon ROSENTHAL , Eric BROWN , Tina SCHWABE , Angie YEE , Herve RHINN
IPC: C07K16/28
CPC classification number: C07K16/28 , C07K2317/34 , C07K2317/56
Abstract: The present disclosure is generally directed to compositions that include antibodies, e.g., monoclonal antibodies, antibody fragments, etc., that specifically bind a TMEM106B polypeptide, e.g., a mammalian TMEM106B or human TMEM106B, and use of such compositions in preventing, reducing risk, or treating an individual in need thereof.
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