公开(公告)号：US20230416718A1

公开(公告)日：2023-12-28

申请号：US18037934

申请日：2021-11-19

申请人： AMANO ENZYME INC.

发明人： Tomohiro Matsuoka ,  Hiroyuki Yachi ,  Daiki Senda ,  Kensuke Yuki

IPC分类号： C12N9/80 ,  C12P21/00 ,  A23J3/34

CPC分类号： C12N9/80 ,  C12Y305/01044 ,  C12P21/00 ,  A23J3/34

摘要： Disclosed is a protein glutaminase having improved thermotolerance. A protein glutaminase comprising a polypeptide indicated in any among (1) to (3) has improved thermotolerance. (1) A polypeptide comprising a SEQ ID NO: 1 or 2 amino acid sequence; (2) a polypeptide wherein one or more amino acid residues are substituted, added, inserted or lost in the amino acid sequence indicated by SEQ ID NO: 1 or 2 and exhibiting the same thermotolerance as the amino acid sequence indicated by SEQ ID NO: 1 or 2: and (3) a polypeptide having at least 76% sequence identity with the amino acid sequence indicated by SEQ ID NO: 1 or 2 and having similar thermotolerance to a polypeptide comprising the amino acid sequence indicated by SEQ ID NO: 1 or 2.

公开(公告)号：US20240279624A1

公开(公告)日：2024-08-22

申请号：US18569377

申请日：2022-06-13

申请人： AMANO ENZYME INC.

发明人： Tetsuya Takahashi ,  Hirotaka Matsubara ,  Tomohiro Matsuoka ,  Kiyota Sakai

IPC分类号： C12N9/10 ,  A23L29/00 ,  C12N1/20

CPC分类号： C12N9/1044 ,  A23L29/06 ,  C12N1/20

摘要： It is an object of the present invention to provide an enzyme agent containing a transglutaminase having high reactivity at a low temperature and the use thereof. According to the present invention, provided is an enzyme agent containing, as an active ingredient, a transglutaminase consisting of an amino acid sequence having a sequence identity of 90% or more to the amino acid sequence of SEQ ID NO: 1.