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公开(公告)号：US20240309044A1
公开(公告)日：2024-09-19
申请号：US18602268
申请日：2024-03-12
Applicant: AMGEN INC.
Inventor： Joseph Edward Basconi , Andrew John Maloney , Nicholas Anthony Vecchiarello , Arun Kannoth Nambiar , Glen Bolton
CPC classification number: C07K1/18 , B01D15/363 , B01D15/3809
Abstract: Disclosed herein are methods for purifying a recombinant protein from a composition comprising the recombinant protein and at least one impurity, the methods comprising performing anion exchange chromatography (e.g., in flow-through or weak partitioning chromatography mode) using an anion exchange material comprising a primary amine ligand, such as a polyamine ligand.
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