公开(公告)号：US08791249B2

公开(公告)日：2014-07-29

申请号：US13888275

申请日：2013-05-06

Applicant: Amgen Inc.

Inventor： Gordon Ng ,  Wenyan Shen

IPC: C07H21/04 ,  C12N15/00 ,  C12P21/06

CPC classification number: C07K16/28 ,  A61K2039/505 ,  C07K16/2803 ,  C07K2317/24 ,  C07K2317/41 ,  C07K2317/71 ,  C07K2317/73 ,  C07K2317/76 ,  C07K2317/77 ,  C07K2317/92

Abstract: This invention relates to compositions and methods for treating c-Kit associated disorders such as fibrosis, and more particularly, to compositions containing humanized c-Kit antibodies.

Abstract translation: 本发明涉及用于治疗c-Kit相关疾病如纤维化的组合物和方法，更具体地涉及含有人源化c-Kit抗体的组合物。

公开(公告)号：US10526411B2

公开(公告)日：2020-01-07

申请号：US15665139

申请日：2017-07-31

Applicant: AMGEN INC.

Inventor： Chadwick Terence King ,  Gordon Ng ,  Shaw-Fen Sylvia Hu ,  Hung Nguyen ,  Jeannie Jung

IPC: C07K16/00 ,  C12P21/08 ,  C07K16/28 ,  A61K39/00

Abstract: The present invention provides compositions and methods relating to antigen binding proteins against CCR7, including antibodies, nucleic acids, vectors, methods of making the antigen binding proteins, and methods of using the antigen binding proteins.