公开(公告)号：US20190143047A1

公开(公告)日：2019-05-16

申请号：US16154759

申请日：2018-10-09

Applicant: AMGEN INC.

Inventor： Julian Jazayeri ,  Ronald Forster ,  Jolita Seckute ,  Olivia Alice Henderson ,  Kristen Brown ,  Gregory Gordon ,  Rasmus Øhlenschlæger ,  Peter Dan Kaare Soelberg

IPC: A61M5/315 ,  A61M5/20

Abstract: A plunger configured as described herein provides geometry optimizations to minimize friction magnitude and variability during use by maintaining low deformation under large extrusion forces. More specifically, plunger embodiments described herein minimize a contact area between the plunger and a syringe or chamber, while also maintaining high contract pressures to maintain container closure integrity. Moreover, the plunger embodiments are configured to have minimal or no increase in the contact area under high loads associated with the delivery of viscous products.

公开(公告)号：US11191904B2

公开(公告)日：2021-12-07

申请号：US16154759

申请日：2018-10-09

Applicant: AMGEN INC.

Inventor： Julian Jazayeri ,  Ronald Forster ,  Jolita Seckute ,  Olivia Alice Henderson ,  Kristen Brown ,  Gregory Gordon ,  Rasmus Øhlenschlæger ,  Peter Dan Kaare Soelberg

IPC: A61M5/31 ,  A61M5/315 ,  F16J1/00 ,  A61M5/142 ,  A61M5/20

Abstract: A plunger configured as described herein provides geometry optimizations to minimize friction magnitude and variability during use by maintaining low deformation under large extrusion forces. More specifically, plunger embodiments described herein minimize a contact area between the plunger and a syringe or chamber, while also maintaining high contract pressures to maintain container closure integrity. Moreover, the plunger embodiments are configured to have minimal or no increase in the contact area under high loads associated with the delivery of viscous products.