公开(公告)号：US11459595B2

公开(公告)日：2022-10-04

申请号：US17554836

申请日：2021-12-17

Applicant: AMGEN INC.

Inventor： Jian Wu ,  Sean Davern ,  Simina Crina Petrovan ,  Michael Charles Brandenstein ,  Katherine Rose Lindahl ,  Shawn Erik Lillie

IPC: C12P21/00 ,  C12N5/00 ,  C07K16/00 ,  C12N1/38

Abstract: The present invention relates to methods of modulating the mannose content of recombinant proteins.

公开(公告)号：US11952605B2

公开(公告)日：2024-04-09

申请号：US18172670

申请日：2023-02-22

Applicant: AMGEN INC.

Inventor： Jian Wu ,  Sean Davern ,  Simina Crina Petrovan ,  Michael Charles Brandenstein ,  Katherine Rose Lindahl ,  Shawn Erik Lillie

IPC: C12P21/00 ,  C07K16/00 ,  C12N1/38 ,  C12N5/00

CPC classification number: C12P21/005 ,  C07K16/00 ,  C12N1/38 ,  C12N5/0037 ,  C07K2317/14 ,  C07K2317/41 ,  C12N2500/32 ,  C12N2500/34 ,  C12N2510/02

Abstract: The present invention relates to methods of modulating the mannose content of recombinant proteins.

公开(公告)号：US11319568B2

公开(公告)日：2022-05-03

申请号：US16654933

申请日：2019-10-16

Applicant: AMGEN INC.

Inventor： Jian Wu ,  Sean Davern ,  Simina Crina Petrovan ,  Michael Charles Brandenstein ,  Katherine Rose Lindahl ,  Shawn Erik Lillie

IPC: C12P21/00 ,  C12N5/00 ,  C12N1/38 ,  C07K16/00

Abstract: The present invention relates to methods of modulating the mannose content of recombinant proteins.

公开(公告)号：US09822388B2

公开(公告)日：2017-11-21

申请号：US14776404

申请日：2014-03-10

Applicant: AMGEN INC.

Inventor： Jian Wu ,  Sean Davern ,  Simina Crina Petrovan ,  Michael Charles Brandenstein ,  Katherine Rose Lindahl ,  Shawn Erik Lillie

IPC: C12P21/00 ,  C12N1/38 ,  C07K16/00 ,  C12N5/00

CPC classification number: C12P21/005 ,  C07K16/00 ,  C07K2317/14 ,  C07K2317/41 ,  C12N1/38 ,  C12N5/0037 ,  C12N2500/32 ,  C12N2500/34 ,  C12N2510/02

Abstract: The present invention relates to methods of modulating the mannose content of recombinant proteins.