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公开(公告)号:US20180305465A1
公开(公告)日:2018-10-25
申请号:US15779325
申请日:2016-11-23
Applicant: AMGEN INC. , XENCOR, INC.
Inventor: Jennitte Leann Stevens , Mercedesz Balazs , Olivier Nolan-Stevaux , Gregory Moore , John Desjarlais , Matthew J. Bernett , Seung Y. Chu , Rumana Rashid , Umesh Muchhal
CPC classification number: C07K16/468 , A61K2039/505 , A61P35/00 , C07K16/2809 , C07K16/40 , C07K2317/31 , C07K2317/55 , C07K2317/622 , C07K2317/73 , C07K2317/92
Abstract: The present invention is directed to heterodimeric antibodies that bind CD3 and CD38.