专利检索 ap:("ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY") AND inv:"Huilai Tian" 第 1 页

1.

发明授权
Antibody based reagents that specifically recognize toxic oligomeric forms of tau 有权

公开(公告)号：US12084490B2

公开(公告)日：2024-09-10

申请号：US17327462

申请日：2021-05-21

申请人： ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY

发明人： Michael Sierks , Huilai Tian

IPC分类号： C07K16/18 , A61K39/00 , C07K16/00 , C12N15/10 , G01N33/68

CPC分类号： C07K16/18 , C07K16/005 , C12N15/1037 , G01N33/6896 , A61K2039/505 , C07K2317/21 , C07K2317/30 , C07K2317/62 , C07K2317/622 , C07K2317/76 , G01N2333/47 , G01N2333/4703 , G01N2800/28 , G01N2800/2814 , G01N2800/2821 , G01N2800/7047

摘要： The invention relates to antibodies, antibody fragments and binding agents that specifically recognize oligomeric tau but do not bind to monomeric tau, fibrillar tau or non-disease associated forms of tau.

2.

发明授权
Antibody based reagents that specifically recognize toxic oligomeric forms of tau 有权

公开(公告)号：US11046755B2

公开(公告)日：2021-06-29

申请号：US16672034

申请日：2019-11-01

申请人： ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY

发明人： Michael Sierks , Huilai Tian

IPC分类号： C07K16/18 , C07K16/00 , G01N33/68 , C12N15/10 , A61K39/00

摘要： The invention relates to antibodies, antibody fragments and binding agents that specifically recognize oligomeric tau but do not bind to monomeric tau, fibrillar tau or non-disease associated forms of tau.

3.

发明授权
Antibody based reagents that specifically recognize toxic oligomeric forms of tau 有权

公开(公告)号：US09915668B2

公开(公告)日：2018-03-13

申请号：US15479110

申请日：2017-04-04

申请人： ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY

发明人： Michael Sierks , Huilai Tian

IPC分类号： G01N33/68 , C07K16/18

CPC分类号： C07K16/18 , A61K2039/505 , C07K16/005 , C07K2317/21 , C07K2317/30 , C07K2317/62 , C07K2317/622 , C07K2317/76 , C12N15/1037 , G01N33/6896 , G01N2333/47 , G01N2333/4703 , G01N2800/28 , G01N2800/2814 , G01N2800/2821 , G01N2800/7047

摘要： The invention relates to antibodies, antibody fragments and binding agents that specifically recognize oligomeric tau but do not bind to monomeric tau, fibrillar tau or non-disease associated forms of tau.

4.

发明授权
Antibody based reagents that specifically recognize toxic oligomeric forms of tau 有权

公开(公告)号：US09650436B2

公开(公告)日：2017-05-16

申请号：US14434742

申请日：2013-10-15

申请人： ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY

发明人： Michael Sierks , Huilai Tian

IPC分类号： C07K16/18 , G01N33/68 , C07K16/00 , C12N15/10 , A61K39/00

CPC分类号： C07K16/18 , A61K2039/505 , C07K16/005 , C07K2317/21 , C07K2317/30 , C07K2317/62 , C07K2317/622 , C07K2317/76 , C12N15/1037 , G01N33/6896 , G01N2333/47 , G01N2333/4703 , G01N2800/28 , G01N2800/2814 , G01N2800/2821 , G01N2800/7047

摘要： The invention relates to antibodies, antibody fragments and binding agents that specifically recognize oligomeric tau but do not bind to monomelic tau, fibrillar tau or non-disease associated forms of tau.