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公开(公告)号：US20220099675A1
公开(公告)日：2022-03-31
申请号：US17489273
申请日：2021-09-29
Inventor： Xiahui CHEN , Shoukai KANG , Md Ashif IKBAL , Zhi ZHAO , Liangcai GU , Chao WANG
IPC: G01N33/569 , G01N33/543 , G01N21/78
Abstract: Provided herein are methods of detecting Ebola virus in a sample. The methods include contacting the sample with a plurality of gold nanoparticles (AuNPs) that are conjugated with at least two sets of antibodies, or antigen binding portions thereof, that binds to at least first or second epitopes of glycoproteins, such as secreted glycoproteins (sGPs) from the Ebola virus under conditions sufficient for the antibodies, or the antigen binding portions thereof, to bind to the first or second epitopes of the glycoproteins from the Ebola virus in the sample to produce bound glycoproteins. The methods also include detecting the glycoproteins from the Ebola virus when aggregations of the bound glycoproteins form with one another. Related reaction mixtures, devices, kits, and systems are also provided.
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公开(公告)号：US20220275972A1
公开(公告)日：2022-09-01
申请号：US17628627
申请日：2020-07-08
Abstract: Reflectors for concentrated solar power as well as systems and methods for additively manufacturing the reflectors is provided. The disclosed method can directly print metal films from an aqueous precursor solution onto a substrate with little to no post-fabrication treatment to achieve highly reflective surfaces with low surface roughness. The method provides precise control to form a metal film having an RMS surface roughness of about 2 to about 5 nm and a relative reflectivity of about 90% to about 96% at 550 nm on a substrate having an area of at least 1 square meter.
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公开(公告)号：US20230375547A1
公开(公告)日：2023-11-23
申请号：US18247161
申请日：2021-09-29
Inventor： Xiahui CHEN , Shoukai KANG , MD Ashif IKBAL , Zhi ZHAO , Liangcai GU , Chao WANG
IPC: G01N33/569 , G01N33/543
CPC classification number: G01N33/56983 , G01N33/54346 , G01N33/54386 , G01N2333/08 , G01N2469/10
Abstract: Provided herein are methods of detecting Ebola virus in a sample. The methods include contacting the sample with a plurality of gold nanoparticles (AuNPs) that are conjugated with antibodies, or antigen binding portions thereof, that bind to an epitope of a secreted glycoprotein (sGP) from the Ebola virus under conditions sufficient for the antibodies, or the antigen binding portions thereof, to bind to the epitope of the sGP from the Ebola virus in the sample to produce bound sGP. The methods also include detecting the sGP from the Ebola virus when aggregations of the bound sGP form with one another. Related reaction mixtures, devices, kits, and systems are also provided.
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