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公开(公告)号：US10772851B2
公开(公告)日：2020-09-15
申请号：US15886469
申请日：2018-02-01
申请人： Aaron Kurt Neumann , Harry Craig Pappas , Matthew Graus , David G. Whitten , Kirk S. Schanze , Rina Sylejmani
发明人： Aaron Kurt Neumann , Harry Craig Pappas , Matthew Graus , David G. Whitten , Kirk S. Schanze , Rina Sylejmani
IPC分类号： A61K31/14 , A61K31/75 , A61K31/795 , A61P31/10
摘要： Various embodiments disclosed relate to treatment of fungal infections. The present invention provides a method of treating a fungal infection including contacting a fungus including a β-glucan that is at least partially masked from immune system detection with a therapeutically effective amount of a compound that at least partially unmasks the β-glucan to increase immunogenicity of the fungus.
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公开(公告)号：US20180221309A1
公开(公告)日：2018-08-09
申请号：US15886469
申请日：2018-02-01
IPC分类号： A61K31/14 , A61K31/75 , A61K31/795 , A61P31/10
CPC分类号： A61K31/14 , A61K31/75 , A61K31/795 , A61P31/10
摘要： Various embodiments disclosed relate to treatment of fungal infections. The present invention provides a method of treating a fungal infection including contacting a fungus including a β-glucan that is at least partially masked from immune system detection with a therapeutically effective amount of a compound that at least partially unmasks the β-glucan to increase immunogenicity of the fungus.
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公开(公告)号：US11592399B2
公开(公告)日：2023-02-28
申请号：US17272527
申请日：2019-08-29
申请人： STC.UNM , Aaron Kurt Neumann , Anatoliy O. Pinchuk
摘要： Highly sensitive assays for pathogen detection, identification and/or analysis including, but not limited to, sensing of metabolite patterns associated with high-risk drug resistance phenotypes.
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公开(公告)号：US20190292579A1
公开(公告)日：2019-09-26
申请号：US16333665
申请日：2017-09-18
摘要： Methods and apparatus for rapid, culture free pathogen detection. The methods utilize optical spectroscopy techniques to identify and/or characterize pathogens in a sample via the detection of unique properties and/or analytes that are specific to particular pathogens.
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公开(公告)号：US11275028B2
公开(公告)日：2022-03-15
申请号：US16333681
申请日：2017-09-18
申请人： Aaron Kurt Neumann , Anatoliy O Pinchuk , Ke Jiang
发明人： Aaron Kurt Neumann , Anatoliy O Pinchuk , Ke Jiang
IPC分类号： C12Q1/00 , G01N21/65 , C12Q1/04 , G01N33/569 , G01N33/543
摘要： Methods and apparatus for rapid, culture and/or label free pathogen detection. The methods utilize optical spectroscopy techniques to identify and/or characterize pathogens in a sample via the detection of unique properties and/or analytes that are specific to particular pathogens.
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公开(公告)号：US20190265166A1
公开(公告)日：2019-08-29
申请号：US16333681
申请日：2017-09-18
申请人： Aaron Kurt Neumann , Anatoliy O Pinchuk , Ke Jiang
发明人： Aaron Kurt Neumann , Anatoliy O Pinchuk , Ke Jiang
摘要： Methods and apparatus for rapid, culture and/or label free pathogen detection. The methods utilize optical spectroscopy techniques to identify and/or characterize pathogens in a sample via the detection of unique properties and/or analytes that are specific to particular pathogens.
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