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    Automatic electrode integrity management systems and methods
    8.
    发明授权
    Automatic electrode integrity management systems and methods 有权
    自动电极完整性管理系统和方法

    公开(公告)号：US08442635B2

    公开(公告)日：2013-05-14

    申请号：US13031762

    申请日：2011-02-22

    申请人： Derek D. Bohn ,  M. Jason Brooke ,  Rajesh K. Gandhi ,  Alok S. Sathaye ,  Aaron R. McCabe

    发明人： Derek D. Bohn ,  M. Jason Brooke ,  Rajesh K. Gandhi ,  Alok S. Sathaye ,  Aaron R. McCabe

    IPC分类号： A61N1/08

    CPC分类号： A61N1/37282 ,  A61N1/368 ,  A61N1/3684 ,  A61N1/3706 ,  A61N2001/083

    摘要： This document discusses, among other things, systems and methods for automatic electrode integrity management. Interelectrode impedance is measured for various electrode combinations of an implantable cardiac function management device. The impedance data is processed, such as at an external remote server, to determine whether an electrode is failing or has failed, to select an alternate electrode configuration, to alert a physician or patient, to predict a time-to-failure such as by using population data, or to reprogram electrode configuration or other device parameters of the implantable cardiac function management device.

    摘要翻译： 本文件还讨论了自动电极完整性管理的系统和方法。 测量可植入心脏功能管理装置的各种电极组合的电极内阻抗。 处理阻抗数据，例如在外部远程服务器处，以确定电极是否发生故障或失败，选择备用电极配置，以警告医师或患者预测失效时间，例如通过 使用种群数据，或重新编程可植入心脏功能管理装置的电极配置或其他装置参数。

    Local and non-local sensing for cardiac pacing
    9.
    发明授权
    Local and non-local sensing for cardiac pacing 有权
    心脏起搏的局部和非局部感觉

    公开(公告)号：US08527048B2

    公开(公告)日：2013-09-03

    申请号：US11478286

    申请日：2006-06-29

    申请人： Alok S. Sathaye ,  Aaron R. McCabe ,  Yinghong Yu

    发明人： Alok S. Sathaye ,  Aaron R. McCabe ,  Yinghong Yu

    IPC分类号： A61N1/365

    CPC分类号： A61B5/0452 ,  A61N1/36585 ,  A61N1/368 ,  A61N1/3682 ,  A61N1/3684

    摘要： Systems and methods for determining pacing timing intervals based on the temporal relationship between the timing of local and non-local cardiac signal features are described. A device includes a plurality of implantable electrodes electrically coupled to the heart and configured to sense local and non-local cardiac signals. Sense circuitry coupled to first and second electrode pairs senses a local cardiac signal via a first electrode pair and a non-local cardiac signal via a second electrode pair. Detection circuitry is used to detect a feature of the local signal associated with activation of a heart chamber and to detect a feature of the non-local signal associated with activation of the heart chamber. A control processor times delivery of one or more pacing pulses based on a temporal relationship between timing of the local signal feature and timing of the non-local signal feature.

    摘要翻译： 描述了基于局部和非局部心脏信号特征的定时之间的时间关系来确定起搏定时间隔的系统和方法。 一种装置包括电耦合到心脏并被配置为感测局部和非局部心脏信号的多个可植入电极。 耦合到第一和第二电极对的感测电路经由第二电极对经由第一电极对和非局部心脏信号感测局部心脏信号。 检测电路用于检测与心室的激活相关联的局部信号的特征，并且检测与心室的激活相关的非局部信号的特征。 控制处理器基于本地信号特征的定时和非本地信号特征的定时之间的时间关系来递送一个或多个起搏脉冲的递送。

    Determination of cardiac pacing parameters based on non-localized sensing
    10.
    发明申请
    Determination of cardiac pacing parameters based on non-localized sensing 审中-公开
    基于非局部感知的心脏起搏参数的确定

    公开(公告)号：US20080004665A1

    公开(公告)日：2008-01-03

    申请号：US11478428

    申请日：2006-06-29

    申请人： Aaron R. McCabe ,  Alok S. Sathaye ,  Yinghong Yu

    发明人： Aaron R. McCabe ,  Alok S. Sathaye ,  Yinghong Yu

    IPC分类号： A61N1/00

    CPC分类号： A61N1/3627 ,  A61N1/3682

    摘要： An atrioventricular delay (AVD) for cardiac pacing therapy is determined based, at least in part, on one or more cardiac activation signals sensed using body-implantable electrodes providing non-local sensing. A conduction delay is estimated using a non-local cardiac activation signal and the AVD is determined based on the conduction delay. Estimating the conduction delay may involve measuring a P-wave width or measuring a QRS complex width of the non-local signal. If multiple signals are sensed, the conduction delay may be estimated from a selected signal or may be estimated by forming a representative signal such as through averaging or other methods. The AVD may be determined as a function of the estimated conduction delay.

    摘要翻译： 至少部分地基于使用提供非局部感测的体内植入电极感测到的一种或多种心脏激活信号来确定用于心脏起搏治疗的房室延迟（AVD）。 使用非局部心脏激活信号估计导通延迟，并且基于导通延迟来确定AVD。 估计传导延迟可能涉及测量P波宽度或测量非本地信号的QRS复数宽度。 如果感测到多个信号，则可以从所选择的信号估计导通延迟，或者可以通过形成诸如通过平均或其它方法的代表性信号来估计导通延迟。 AVD可以被确定为估计的传导延迟的函数。