公开(公告)号：US20160206584A1

公开(公告)日：2016-07-21

申请号：US15001392

申请日：2016-01-20

申请人： AbbVie, Inc.

发明人： Rajkumar CONJEEVARAM ,  Alexandru DEAC ,  Ye HUANG ,  Sean E. MACKEY ,  Randy A. MENGES ,  Jayne ZIMMERMAN

IPC分类号： A61K31/198 ,  A61K47/10 ,  A61K47/38 ,  A61K47/32 ,  A61K9/00 ,  A61K9/10

CPC分类号： A61K31/198 ,  A61K9/0019 ,  A61K9/0053 ,  A61K9/10 ,  A61K45/06 ,  A61K47/10 ,  A61K47/32 ,  A61K47/38 ,  A61K2300/00

摘要： The present disclosure relates to (a) an improved pharmaceutical composition comprising a levodopa active agent and a carbidopa active agent (b) methods of producing the pharmaceutical composition and (c) methods of treating Parkinson's disease and associated conditions comprising administering the pharmaceutical composition to a subject with Parkinson's disease.

摘要翻译： 本公开涉及（a）包含左旋多巴活性剂和卡比多巴活性剂的改进的药物组合物（b）制备药物组合物的方法和（c）治疗帕金森病和相关病症的方法，包括将药物组合物施用于 患有帕金森病。

公开(公告)号：US20230285667A1

公开(公告)日：2023-09-14

申请号：US18140944

申请日：2023-04-28

申请人： ABBVIE INC.

发明人： Ted HANAGAN ,  Wayne KLINGLER ,  Thomas Paul GRAZIER ,  Gurjinder DHAMI ,  Scott SMIEJA ,  Jeff SCHACHERL ,  Sean MACKEY ,  Megan FEILEN ,  Ji ZHOU ,  Rajkumar CONJEEVARAM ,  Martin GIBLER

IPC分类号： A61M5/168 ,  A61M5/162 ,  A61M5/142

CPC分类号： A61M5/16804 ,  A61M5/162 ,  A61M5/14228 ,  A61M5/14232 ,  A61J1/10

摘要： Drug delivery reservoir for delivery of a beneficial agent to a user includes a drug delivery reservoir housing having a fluid reservoir defined therein. The drug delivery reservoir housing has a drug delivery reservoir base region. The drug delivery reservoir includes a dip tube extending inside the fluid reservoir. The dip tube includes a tubular wall defining a flow lumen. The tubular wall has at least one aperture defined therein and spaced proximally from a distal end of the tubular wall in fluid communication with the fluid reservoir. The drug delivery reservoir includes an adaptor disposed external to the drug delivery reservoir housing and coupled to a proximal end of the dip tube.

公开(公告)号：US20210046029A1

公开(公告)日：2021-02-18

申请号：US16822892

申请日：2020-03-18

申请人： AbbVie Inc.

发明人： Rajkumar CONJEEVARAM ,  Alexandru DEAC ,  Ye HUANG ,  Sean E. MACKEY ,  Randy A. MENGES ,  Jayne ZIMMERMAN

IPC分类号： A61K31/198 ,  A61K9/00 ,  A61K9/10 ,  A61K47/38 ,  A61K47/32 ,  A61K47/10 ,  A61K45/06

摘要： The present disclosure relates to (a) an improved pharmaceutical composition comprising a levodopa active agent and a carbidopa active agent (b) methods of producing the pharmaceutical composition and (c) methods of treating Parkinson's disease and associated conditions comprising administering the pharmaceutical composition to a subject with Parkinson's disease.