公开(公告)号：US20070093875A1

公开(公告)日：2007-04-26

申请号：US11256907

申请日：2005-10-24

申请人： Abhi Chavan ,  Anthony Caparso ,  Avram Scheiner

发明人： Abhi Chavan ,  Anthony Caparso ,  Avram Scheiner

IPC分类号： A61N1/00

CPC分类号： A61N1/36117 ,  A61N1/3605 ,  A61N1/36071 ,  A61N1/36135 ,  A61N1/37205 ,  A61N1/37217 ,  A61N1/37288 ,  A61N1/3787

摘要： One aspect of the present subject matter relates to an implantable medical device. An embodiment of the device comprises a rechargeable power supply adapted to be recharged through an ultrasound signal, a neural stimulator connected to the rechargeable power supply, and a controller connected to the rechargeable power supply. The neural stimulator is adapted to generate a neural stimulation signal for delivery to a neural stimulation target through an electrode. The controller is further connected to the neural stimulator to control the neural stimulator according to a neural stimulation protocol. Other aspects are provided herein.

摘要翻译： 本主题的一个方面涉及可植入医疗装置。 该装置的实施例包括适于通过超声信号再充电的可再充电电源，连接到可再充电电源的神经刺激器和连接到可再充电电源的控制器。 神经刺激器适于产生用于通过电极递送到神经刺激靶的神经刺激信号。 控制器进一步连接到神经刺激器，以根据神经刺激方案来控制神经刺激器。 本文提供了其他方面。

公开(公告)号：US20120158090A1

公开(公告)日：2012-06-21

申请号：US13402196

申请日：2012-02-22

申请人： Abhi Chavan ,  Anthony Caparso ,  Avram Scheiner

发明人： Abhi Chavan ,  Anthony Caparso ,  Avram Scheiner

IPC分类号： A61N1/378

CPC分类号： A61N1/36117 ,  A61N1/3605 ,  A61N1/36071 ,  A61N1/36135 ,  A61N1/37205 ,  A61N1/37217 ,  A61N1/37288 ,  A61N1/3787

摘要： One aspect of the present subject matter relates to an implantable medical device. An embodiment of the device comprises a rechargeable power supply adapted to be recharged through an ultrasound signal, a neural stimulator connected to the rechargeable power supply, and a controller connected to the rechargeable power supply. The neural stimulator is adapted to generate a neural stimulation signal for delivery to a neural stimulation target through an electrode. The controller is further connected to the neural stimulator to control the neural stimulator according to a neural stimulation protocol. Other aspects are provided herein.

摘要翻译： 本主题的一个方面涉及可植入医疗装置。 该装置的实施例包括适于通过超声信号再充电的可再充电电源，连接到可再充电电源的神经刺激器和连接到可再充电电源的控制器。 神经刺激器适于产生用于通过电极递送到神经刺激靶的神经刺激信号。 控制器进一步连接到神经刺激器，以根据神经刺激方案来控制神经刺激器。 本文提供了其他方面。

公开(公告)号：US20100049275A1

公开(公告)日：2010-02-25

申请号：US12613094

申请日：2009-11-05

申请人： Abhi Chavan ,  Anthony Caparso ,  Avram Scheiner

发明人： Abhi Chavan ,  Anthony Caparso ,  Avram Scheiner

IPC分类号： A61N1/34 ,  A61N1/36 ,  A61N1/378

CPC分类号： A61N1/36117 ,  A61N1/3605 ,  A61N1/36071 ,  A61N1/36135 ,  A61N1/37205 ,  A61N1/37217 ,  A61N1/37288 ,  A61N1/3787

摘要： One aspect of the present subject matter relates to an implantable medical device. An embodiment of the device comprises a rechargeable power supply adapted to be recharged through an ultrasound signal, a neural stimulator connected to the rechargeable power supply, and a controller connected to the rechargeable power supply. The neural stimulator is adapted to generate a neural stimulation signal for delivery to a neural stimulation target through an electrode. The controller is further connected to the neural stimulator to control the neural stimulator according to a neural stimulation protocol. Other aspects are provided herein.

摘要翻译： 本主题的一个方面涉及可植入医疗装置。 该装置的实施例包括适于通过超声信号再充电的可再充电电源，连接到可再充电电源的神经刺激器和连接到可再充电电源的控制器。 神经刺激器适于产生用于通过电极递送到神经刺激靶的神经刺激信号。 控制器进一步连接到神经刺激器，以根据神经刺激方案来控制神经刺激器。 本文提供了其他方面。

公开(公告)号：US07616990B2

公开(公告)日：2009-11-10

申请号：US11256907

申请日：2005-10-24

申请人： Abhi Chavan ,  Anthony Caparso ,  Avram Scheiner

发明人： Abhi Chavan ,  Anthony Caparso ,  Avram Scheiner

IPC分类号： A61N1/00

CPC分类号： A61N1/36117 ,  A61N1/3605 ,  A61N1/36071 ,  A61N1/36135 ,  A61N1/37205 ,  A61N1/37217 ,  A61N1/37288 ,  A61N1/3787

摘要： One aspect of the present subject matter relates to an implantable medical device. An embodiment of the device comprises a rechargeable power supply adapted to be recharged through an ultrasound signal, a neural stimulator connected to the rechargeable power supply, and a controller connected to the rechargeable power supply. The neural stimulator is adapted to generate a neural stimulation signal for delivery to a neural stimulation target through an electrode. The controller is further connected to the neural stimulator to control the neural stimulator according to a neural stimulation protocol. Other aspects are provided herein.

摘要翻译： 本主题的一个方面涉及可植入医疗装置。 该装置的实施例包括适于通过超声信号再充电的可再充电电源，连接到可再充电电源的神经刺激器和连接到可再充电电源的控制器。 神经刺激器适于产生用于通过电极递送到神经刺激靶的神经刺激信号。 控制器进一步连接到神经刺激器，以根据神经刺激方案来控制神经刺激器。 本文提供了其他方面。

公开(公告)号：US20060282145A1

公开(公告)日：2006-12-14

申请号：US11151103

申请日：2005-06-13

申请人： Anthony Caparso ,  Avram Scheiner

发明人： Anthony Caparso ,  Avram Scheiner

IPC分类号： A61N1/05

CPC分类号： A61N1/0551 ,  A61N1/0556 ,  A61N1/0558

摘要： A vascularly stabilized peripheral nerve cuff assembly is provided. One aspect of this disclosure relates to an electrode assembly used in the delivery of neural stimulation therapy. The electrode assembly includes a body adapted to at least partially encompass a blood vessel and a nerve proximate to the blood vessel. The electrode assembly also includes at least one electrode along at least a portion of the body. The at least one electrode is adapted to be electrically connected to a neural stimulator. According to an embodiment, the electrode assembly includes a spacer within the body, the spacer having a first and second end, the first end secured to an inside surface of the body and the second end adapted to pass between the vessel and the nerve and to be secured to the inside surface of the body. Other aspects and embodiments are provided herein.

公开(公告)号：US07617003B2

公开(公告)日：2009-11-10

申请号：US11130022

申请日：2005-05-16

申请人： Anthony Caparso ,  Julia Moffitt ,  Avram Scheiner

发明人： Anthony Caparso ,  Julia Moffitt ,  Avram Scheiner

IPC分类号： A61N1/05

CPC分类号： A61N1/0551 ,  A61N1/057 ,  A61N1/372

摘要： A system for selective activation of a nerve trunk using a transvascular reshaping lead is provided. One aspect of this disclosure relates to a system for spreading nerve bundles in a nerve trunk. The system includes a lead adapted to be chronically implanted in a blood vessel proximate a nerve trunk, and having an expandable portion adapted to be expanded to reshape the blood vessel to an elongated shape and to reshape the nerve trunk into an elongated shape to spread nerve bundles of the nerve trunk. The system also includes a plurality of electrodes and an implantable device coupled to the lead, where an electrical signal is delivered from the implanted medical device to one of the plurality of electrodes to transvascularly deliver neural stimulation from the electrode to at least one of the nerve bundles of the nerve trunk. Other aspects and embodiments are provided herein.

摘要翻译： 提供了使用经血管重塑引线选择性激活神经干的系统。 本公开的一个方面涉及一种用于在神经干中扩展神经束的系统。 该系统包括适于长期植入靠近神经干的血管中的引线，并且具有适于扩张的扩张部分以将血管重塑为细长形状并将神经干重新形成细长形状以展开神经 束神经干。 该系统还包括耦合到引线的多个电极和可植入装置，其中电信号从植入的医疗装置输送到多个电极中的一个电极，以将神经刺激从电极转运到至少一个神经 束神经干。 本文提供了其它方面和实施例。

公开(公告)号：US07584004B2

公开(公告)日：2009-09-01

申请号：US11151103

申请日：2005-06-13

申请人： Anthony Caparso ,  Avram Scheiner

发明人： Anthony Caparso ,  Avram Scheiner

IPC分类号： A61N1/05 ,  A61N1/18

CPC分类号： A61N1/0551 ,  A61N1/0556 ,  A61N1/0558

摘要： A vascularly stabilized peripheral nerve cuff assembly is provided. One aspect of this disclosure relates to an electrode assembly used in the delivery of neural stimulation therapy. The electrode assembly includes a body adapted to at least partially encompass a blood vessel and a nerve proximate to the blood vessel. The electrode assembly also includes at least one electrode along at least a portion of the body. The at least one electrode is adapted to be electrically connected to a neural stimulator. According to an embodiment, the electrode assembly includes a spacer within the body, the spacer having a first and second end, the first end secured to an inside surface of the body and the second end adapted to pass between the vessel and the nerve and to be secured to the inside surface of the body. Other aspects and embodiments are provided herein.

摘要翻译： 提供血管稳定的外周神经袖带组件。 本公开的一个方面涉及用于递送神经刺激疗法的电极组件。 电极组件包括适于至少部分地包围血管和靠近血管的神经的主体。 电极组件还包括沿着身体的至少一部分的至少一个电极。 至少一个电极适于电连接到神经刺激器。 根据一个实施例，电极组件包括在主体内的间隔件，间隔件具有第一和第二端，第一端固定到主体的内表面，第二端适于在容器和神经之间通过， 固定在身体的内表面。 本文提供了其它方面和实施例。

公开(公告)号：US20060259107A1

公开(公告)日：2006-11-16

申请号：US11130022

申请日：2005-05-16

申请人： Anthony Caparso ,  Julia Moffitt ,  Avram Scheiner

发明人： Anthony Caparso ,  Julia Moffitt ,  Avram Scheiner

IPC分类号： A61N1/05

CPC分类号： A61N1/0551 ,  A61N1/057 ,  A61N1/372

摘要： A system for selective activation of a nerve trunk using a transvascular reshaping lead is provided. One aspect of this disclosure relates to a system for spreading nerve bundles in a nerve trunk. The system includes a lead adapted to be chronically implanted in a blood vessel proximate a nerve trunk, and having an expandable portion adapted to be expanded to reshape the blood vessel to an elongated shape and to reshape the nerve trunk into an elongated shape to spread nerve bundles of the nerve trunk. The system also includes a plurality of electrodes and an implantable device coupled to the lead, where an electrical signal is delivered from the implanted medical device to one of the plurality of electrodes to transvascularly deliver neural stimulation from the electrode to at least one of the nerve bundles of the nerve trunk. Other aspects and embodiments are provided herein.

公开(公告)号：US20100016927A1

公开(公告)日：2010-01-21

申请号：US12564416

申请日：2009-09-22

申请人： Anthony Caparso ,  Julia Moffitt ,  Avram Scheiner

发明人： Anthony Caparso ,  Julia Moffitt ,  Avram Scheiner

IPC分类号： A61N1/05 ,  A61N1/36

CPC分类号： A61N1/0551 ,  A61N1/057 ,  A61N1/372

摘要： A system for selective activation of a nerve trunk using a transvascular reshaping lead is provided. One aspect of this disclosure relates to a system for spreading nerve bundles in a nerve trunk. The system includes a lead adapted to be chronically implanted in a blood vessel proximate a nerve trunk, and having an expandable portion adapted to be expanded to reshape the blood vessel to an elongated shape and to reshape the nerve trunk into an elongated shape to spread nerve bundles of the nerve trunk. The system also includes a plurality of electrodes and an implantable device coupled to the lead, where an electrical signal is delivered from the implanted medical device to one of the plurality of electrodes to transvascularly deliver neural stimulation from the electrode to at least one of the nerve bundles of the nerve trunk. Other aspects and embodiments are provided herein.

摘要翻译： 提供了使用经血管重塑引线选择性激活神经干的系统。 本公开的一个方面涉及一种用于在神经干中扩展神经束的系统。 该系统包括适于长期植入靠近神经干的血管中的引线，并且具有适于扩张的扩张部分以将血管重塑为细长形状并将神经干重新形成细长形状以展开神经 束神经干。 该系统还包括耦合到引线的多个电极和可植入装置，其中电信号从植入的医疗装置输送到多个电极中的一个电极，以将神经刺激从电极转运到至少一个神经 束神经干。 本文提供了其它方面和实施例。

公开(公告)号：US09572982B2

公开(公告)日：2017-02-21

申请号：US12433766

申请日：2009-04-30

申请人： John E. Burnes ,  Kenneth C. Gardeski ,  Ruth N. Klepfer ,  Patrick E. Macaulay ,  Mary M. Morris ,  Avram Scheiner

发明人： John E. Burnes ,  Kenneth C. Gardeski ,  Ruth N. Klepfer ,  Patrick E. Macaulay ,  Mary M. Morris ,  Avram Scheiner

IPC分类号： A61B19/00 ,  A61N1/36 ,  A61N1/05 ,  A61M25/09

CPC分类号： A61N1/36053 ,  A61M25/09 ,  A61N1/05 ,  A61N1/0551 ,  A61N1/0558 ,  A61N1/057 ,  A61N1/36085 ,  A61N1/36114 ,  A61N1/36125 ,  A61N1/36128

摘要： This disclosure is directed to extra, intra, and transvascular medical lead placement techniques for arranging medical leads and electrical stimulation and/or sensing electrodes proximate nerve tissue within a patient.

摘要翻译： 本公开涉及用于在患者体内靠近神经组织布置医疗引线和电刺激和/或感测电极的额外的，内部的和经血管内的医疗引线放置技术。