公开(公告)号：US12179009B2

公开(公告)日：2024-12-31

申请号：US17734819

申请日：2022-05-02

Applicant: ABIOMED, Inc. ,  Massachusetts Institute of Technology ,  The Brigham and Women's Hospital, Inc.

Inventor： Ahmad El Katerji ,  Qing Tan ,  Christian Moyer ,  Alexander Ship ,  Sonya Sanat Bhavsar ,  Noam Josephy ,  Elazer R. Edelman ,  Brian Yale Chang ,  Steven Keller

IPC: A61M60/50 ,  A61B5/021 ,  A61B5/0215 ,  A61M60/148 ,  G16H40/63 ,  G16H50/50 ,  A61M60/135

Abstract: The systems and methods described herein determine metrics of cardiac performance via a mechanical circulatory support device and use the cardiac performance to calibrate, control and deliver mechanical circulatory support for the heart. The systems include a controller configured to operate the device, receive inputs indicative of device operating conditions and hemodynamic parameters, and determine vascular performance, including vascular resistance and compliance, and native cardiac output. The systems and methods operate by using the mechanical circulatory support device (e.g., a heart pump) to introduce controlled perturbations of the vascular system and, in response, determine heart parameters such as stroke volume, vascular resistance and compliance, left ventricular end diastolic pressure, and ultimately determine native cardiac output.

公开(公告)号：US20230157557A1

公开(公告)日：2023-05-25

申请号：US17979021

申请日：2022-11-02

Applicant: ABIOMED, Inc.

Inventor： Christian Moyer ,  Scott C. Corbett ,  Ahmad El Katerji ,  David Weber

IPC: A61B5/0215 ,  A61B5/029 ,  A61M60/857 ,  A61M60/546 ,  A61M60/585 ,  A61M60/538 ,  A61M60/531 ,  A61M60/422 ,  A61M60/216 ,  A61M60/13

CPC classification number: A61B5/0215 ,  A61B5/029 ,  A61M60/857 ,  A61M60/546 ,  A61M60/585 ,  A61M60/538 ,  A61M60/531 ,  A61M60/422 ,  A61M60/216 ,  A61M60/13 ,  A61M2205/3334 ,  A61M2205/3344 ,  A61M2210/127 ,  A61M2205/3365 ,  A61M2205/52 ,  A61M2205/502 ,  A61M2205/18 ,  A61M2210/125 ,  A61M2230/30

Abstract: The systems, devices, and methods presented herein use a blood pump to obtain measurements of cardiac function. The system can quantify the functioning of the native heart by measuring certain parameters/signals such as aortic pressure or motor current, then calculate and display one or more cardiac parameters and heart function parameters, such as left ventricular pressure, left ventricular end diastolic pressure, or cardiac power output. These parameters provide valuable information to a user regarding current cardiac function, as well as positioning and function of the blood pump. In some embodiments, the system can act as a diagnostic and therapeutic tool. Providing cardiac parameters in real-time, along with warnings about adverse effects and recommendations to support cardiac function, such as increasing or decreasing the volumetric flow rate of blood pumped by the device, administering pharmaceutical therapies, and/or repositioning the blood pump allow clinicians to better support and treat cardiovascular disease.

公开(公告)号：US20210038793A1

公开(公告)日：2021-02-11

申请号：US16936534

申请日：2020-07-23

Applicant: Abiomed, Inc.

Inventor： Christian Moyer ,  Scott C. Corbett ,  Ahmad El Katerji ,  David Weber

IPC: A61M1/10 ,  A61B5/029 ,  A61B5/0215

Abstract: The systems, devices, and methods presented herein use a blood pump to obtain measurements of cardiac function. The system can quantify the functioning of the native heart by measuring certain parameters/signals such as aortic pressure or motor current, then calculate and display one or more cardiac parameters and heart function parameters, such as left ventricular pressure, left ventricular end diastolic pressure, or cardiac power output. These parameters provide valuable information to a user regarding current cardiac function, as well as positioning and function of the blood pump. In some embodiments, the system can act as a diagnostic and therapeutic tool. Providing cardiac parameters in real-time, along with warnings about adverse effects and recommendations to support cardiac function, such as increasing or decreasing the volumetric flow rate of blood pumped by the device, administering pharmaceutical therapies, and/or repositioning the blood pump allow clinicians to better support and treat cardiovascular disease.

公开(公告)号：US20180353667A1

公开(公告)日：2018-12-13

申请号：US16003669

申请日：2018-06-08

Applicant: Abiomed, Inc.

Inventor： Christian Moyer ,  Scott C. Corbett ,  Ahmad El Katerji ,  David Weber

IPC: A61M1/10 ,  A61B5/0215 ,  A61B5/029

Abstract: The systems, devices, and methods presented herein use a blood pump to obtain measurements of cardiac function. The system can quantify the functioning of the native heart by measuring certain parameters/signals such as aortic pressure or motor current, then calculate and display one or more cardiac parameters and heart function parameters, such as left ventricular pressure, left ventricular end diastolic pressure, or cardiac power output. These parameters provide valuable information to a user regarding current cardiac function, as well as positioning and function of the blood pump. In some embodiments, the system can act as a diagnostic and therapeutic tool. Providing cardiac parameters in real-time, along with warnings about adverse effects and recommendations to support cardiac function, such as increasing or decreasing the volumetric flow rate of blood pumped by the device, administering pharmaceutical therapies, and/or repositioning the blood pump allow clinicians to better support and treat cardiovascular disease.

公开(公告)号：US11529062B2

公开(公告)日：2022-12-20

申请号：US16936534

申请日：2020-07-23

Applicant: Abiomed, Inc.

Inventor： Christian Moyer ,  Scott C. Corbett ,  Ahmad El Katerji ,  David Weber

IPC: A61B5/0215 ,  A61B5/029 ,  A61M60/857 ,  A61M60/546 ,  A61M60/585 ,  A61M60/538 ,  A61M60/531 ,  A61M60/422 ,  A61M60/216 ,  A61M60/13

Abstract: The systems, devices, and methods presented herein use a blood pump to obtain measurements of cardiac function. The system can quantify the functioning of the native heart by measuring certain parameters/signals such as aortic pressure or motor current, then calculate and display one or more cardiac parameters and heart function parameters, such as left ventricular pressure, left ventricular end diastolic pressure, or cardiac power output. These parameters provide valuable information to a user regarding current cardiac function, as well as positioning and function of the blood pump. In some embodiments, the system can act as a diagnostic and therapeutic tool. Providing cardiac parameters in real-time, along with warnings about adverse effects and recommendations to support cardiac function, such as increasing or decreasing the volumetric flow rate of blood pumped by the device, administering pharmaceutical therapies, and/or repositioning the blood pump allow clinicians to better support and treat cardiovascular disease.

公开(公告)号：US20220257921A1

公开(公告)日：2022-08-18

申请号：US17734819

申请日：2022-05-02

Applicant: ABIOMED, Inc. ,  Massachusetts Institute of Technology ,  The Brigham and Women's Hospital, Inc.

Inventor： Ahmad El Katerji ,  Qing Tan ,  Christian Moyer ,  Alexander Ship ,  Sonya Sanat Bhavsar ,  Noam Josephy ,  Elazer R. Edelman ,  Brian Yale Chang ,  Steven Keller

IPC: A61M60/50 ,  G16H50/50 ,  G16H40/63 ,  A61B5/021 ,  A61B5/0215 ,  A61M60/148

Abstract: The systems and methods described herein determine metrics of cardiac performance via a mechanical circulatory support device and use the cardiac performance to calibrate, control and deliver mechanical circulatory support for the heart. The systems include a controller configured to operate the device, receive inputs indicative of device operating conditions and hemodynamic parameters, and determine vascular performance, including vascular resistance and compliance, and native cardiac output. The systems and methods operate by using the mechanical circulatory support device (e.g., a heart pump) to introduce controlled perturbations of the vascular system and, in response, determine heart parameters such as stroke volume, vascular resistance and compliance, left ventricular end diastolic pressure, and ultimately determine native cardiac output.

公开(公告)号：US11357968B2

公开(公告)日：2022-06-14

申请号：US16446419

申请日：2019-06-19

Applicant: Abiomed, Inc. ,  Massachusetts Institute of Technology ,  The Brigham and Women's Hospital Inc.

Inventor： Ahmad El Katerji ,  Qing Tan ,  Christian Moyer ,  Alexander Ship ,  Sonya Sanat Bhavsar ,  Noam Josephy ,  Elazer R. Edelman ,  Brian Yale Chang ,  Steven Keller

IPC: A61M60/50 ,  G16H50/50 ,  G16H40/63 ,  A61B5/021 ,  A61B5/0215 ,  A61M60/148 ,  A61M60/135

Abstract: The systems and methods described herein determine metrics of cardiac performance via a mechanical circulatory support device and use the cardiac performance to calibrate, control and deliver mechanical circulatory support for the heart. The systems include a controller configured to operate the device, receive inputs indicative of device operating conditions and hemodynamic parameters, and determine vascular performance, including vascular resistance and compliance, and native cardiac output. The systems and methods operate by using the mechanical circulatory support device (e.g., a heart pump) to introduce controlled perturbations of the vascular system and, in response, determine heart parameters such as stroke volume, vascular resistance and compliance, left ventricular end diastolic pressure, and ultimately determine native cardiac output.

公开(公告)号：US20200086022A1

公开(公告)日：2020-03-19

申请号：US16446419

申请日：2019-06-19

Applicant: Abiomed, Inc. ,  Massachusetts Institute of Technology ,  The Brigham and Women's Hospital Inc.

Inventor： Ahmad El Katerji ,  Qing Tan ,  Christian Moyer ,  Alexander Ship ,  Sonya Sanat Bhavsar ,  Noam Josephy ,  Elazer R. Edelman ,  Brian Yale Chang ,  Steven Keller

IPC: A61M1/10 ,  A61M1/12

Abstract: The systems and methods described herein determine metrics of cardiac performance via a mechanical circulatory support device and use the cardiac performance to calibrate, control and deliver mechanical circulatory support for the heart. The systems include a controller configured to operate the device, receive inputs indicative of device operating conditions and hemodynamic parameters, and determine vascular performance, including vascular resistance and compliance, and native cardiac output. The systems and methods operate by using the mechanical circulatory support device (e.g., a heart pump) to introduce controlled perturbations of the vascular system and, in response, determine heart parameters such as stroke volume, vascular resistance and compliance, left ventricular end diastolic pressure, and ultimately determine native cardiac output.

公开(公告)号：US20240395414A1

公开(公告)日：2024-11-28

申请号：US18634354

申请日：2024-04-12

Applicant: Abiomed, Inc.

Inventor： Elise Jortberg ,  Christian Moyer

IPC: G16H50/30 ,  A61M60/17 ,  A61M60/585 ,  G16H10/60

Abstract: Methods and apparatus for determining a weaning status for a patient associated with a mechanical circulatory support device are provided. The method includes receiving a set of signals from the mechanical circulatory support device implanted in a heart of a patient, determining, using a computer processor, a set of features based, at least in part, on the set of signals, providing the set of features as input to a machine learning model trained to output a weaning status for the patient, and displaying, on a user interface associated with the mechanical circulatory support device, an indication of the weaning status for the patient output from the machine learning model.

公开(公告)号：US20240347189A1

公开(公告)日：2024-10-17

申请号：US18628505

申请日：2024-04-05

Applicant: Abiomed, Inc.

Inventor： Zhengyang Zhang ,  Govind Bhala ,  Christian Moyer

IPC: G16H40/63 ,  A61M60/13 ,  A61M60/17 ,  A61M60/216 ,  A61M60/414 ,  A61M60/531 ,  A61M60/546 ,  A61M60/554 ,  G16H20/40 ,  G16H50/30

CPC classification number: G16H40/63 ,  A61M60/13 ,  A61M60/17 ,  A61M60/216 ,  A61M60/414 ,  A61M60/531 ,  A61M60/546 ,  A61M60/554 ,  G16H20/40 ,  G16H50/30 ,  A61M2205/04 ,  A61M2205/103 ,  A61M2205/3303 ,  A61M2205/3327 ,  A61M2205/3331 ,  A61M2205/502 ,  A61M2230/30

Abstract: Methods and apparatus for estimating a measure of cardiac contractility based on a set of features determined from a set of signals associated with a mechanical circulatory support device are provided. The method includes determining, using computer processor, a set of features based, at least in part, on the set of signals, providing the set of features as input to a machine learning model trained to output a measure of cardiac contractility, and performing an action based, at least in part, on the measure of cardiac contractility output by the machine learning model.