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公开(公告)号:US07732558B2
公开(公告)日:2010-06-08
申请号:US11316822
申请日:2005-12-27
申请人: Abraham Josephk , Hui-Ju Cho , Yu-Hau Shih , Chao-Hung Kao , Huang-Chien Liang
发明人: Abraham Josephk , Hui-Ju Cho , Yu-Hau Shih , Chao-Hung Kao , Huang-Chien Liang
CPC分类号: A61K49/124
摘要: A dendritic compound of the following structure: PDn-Z-L is disclosed. In the structure above, P is X—(CH2CH2—O)r—, r is an integer ranging from 1000 to 4000, X is OH, NH2, or OR, R is C1 to C10alkyl, Dn is a residue of branched C3 to C30 polyol compounds, n is the quantity of layers of the residue of branched compounds and is an integer equal to or greater than 1, L is a metal cation, Z is the residue of a C3 to C30 compound with multi functional groups. The functional groups illustrated above can be carboxylic groups, amino groups, amide groups, or chelating groups. The carboxylic groups, ester groups, amino groups, or amide groups bind to Dn, and the chelating groups bind to the metal cations.
摘要翻译: 公开了以下结构的树枝状化合物:PDn-Z-L。 在上述结构中,P为X-(CH 2 CH 2 -O)r - ,r为1000〜4000的整数,X为OH,NH 2或OR,R为C1〜C10烷基,Dn为支链C3〜 C30多元醇化合物,n为支链化合物残基的层数,为1以上的整数,L为金属阳离子,Z为具有多官能团的C3〜C30化合物的残基。 上述官能团可以是羧基,氨基,酰胺基或螯合基。 羧基,酯基,氨基或酰胺基与Dn结合,螯合基与金属阳离子结合。
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公开(公告)号:US20060165601A1
公开(公告)日:2006-07-27
申请号:US11316822
申请日:2005-12-27
申请人: Abraham Josephk , Hui-Ju Cho , Yu-Hau Shih , Chao-Hung Kao , Huang-Chien Liang
发明人: Abraham Josephk , Hui-Ju Cho , Yu-Hau Shih , Chao-Hung Kao , Huang-Chien Liang
CPC分类号: A61K49/124
摘要: A dendritic compound of the following structure: PDn-Z-L is disclosed. In the structure above, P is X—(CH2CH2—O)r—, r is an integer ranging from 1000 to 4000, X is OH, NH2, or OR, R is C1 to C10alkyl, Dn is a residue of branched C3 to C30 polyol compounds, n is the quantity of layers of the residue of branched compounds and is an integer equal to or greater than 1, L is a metal cation, Z is the residue of a C3 to C30 compound with multi functional groups. The functional groups illustrated above can be carboxylic groups, amino groups, amide groups, or chelating groups. The carboxylic groups, ester groups, amino groups, or amide groups bind to Dn, and the chelating groups bind to the metal cations.
摘要翻译: 公开了以下结构的树枝状化合物:PD sub> n-Z-L。 在上述结构中,P是X - (CH 2 CH 2 CH 2 -O)n - ,r是1000至4000的整数 ,X是OH,NH 2或OR,R是C 1至C 10烷基,C 1 -C 6烷基, 是分支C 3〜C 30多元醇化合物的残基,n是支链化合物的残基的层数,并且是等于或大于1的整数, L是金属阳离子,Z是具有多官能团的C 3 O 3至C 30+化合物的残基。 上述官能团可以是羧基,氨基,酰胺基或螯合基。 羧基,酯基,氨基或酰胺基结合于D n N,螯合基团与金属阳离子结合。
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公开(公告)号:US07109024B2
公开(公告)日:2006-09-19
申请号:US10408519
申请日:2003-04-07
申请人: Kan-Hung Lee , Yu-Hau Shih , Chuan-Mei Tsai , Yih-Weng Wang , Hsiung Hsiao , Chi-Horng Bair , Shin-Hwan Wang
发明人: Kan-Hung Lee , Yu-Hau Shih , Chuan-Mei Tsai , Yih-Weng Wang , Hsiung Hsiao , Chi-Horng Bair , Shin-Hwan Wang
IPC分类号: C12M1/34
CPC分类号: B82Y30/00 , B01J19/0046 , B01J2219/005 , B01J2219/0052 , B01J2219/00527 , B01J2219/00545 , B01J2219/00576 , B01J2219/00585 , B01J2219/00596 , B01J2219/00605 , B01J2219/0061 , B01J2219/00612 , B01J2219/00621 , B01J2219/00659 , B01J2219/00677 , B01J2219/00711 , B01J2219/00722 , B01J2219/00725 , B01J2219/00729 , C40B40/06 , C40B40/10
摘要: This invention features a biomolecule-bound substrate that includes a support made of an organic polymer and having an unmodified surface; and a plurality of unmodified biomolecules immobilized on the unmodified surface. The organic polymer is acrylic resin, polypropylene, polystyrene, polyethylene, polyvinyl chloride, polysulfone, polycarbonate, cellulose acetate, rubber, latex, polyethylene terephthalate, acrylonitrile butadiene styrene, acrylonitrile styrene, or a combination thereof. The substrate is formed by placing the unmodified biomolecules on the unmodified surface followed by ultraviolet irradiation.
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