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公开(公告)号：US20120196940A1
公开(公告)日：2012-08-02
申请号：US13362429
申请日：2012-01-31
申请人： Adrian Brown , Wayne M. Matthews , Daniel M. Margetson , Stephen Mark McAllister , Ronald K. Raby
发明人： Adrian Brown , Wayne M. Matthews , Daniel M. Margetson , Stephen Mark McAllister , Ronald K. Raby
IPC分类号： A61K47/32
CPC分类号： A61K9/1617 , A61K9/1623 , A61K9/1647 , A61K9/1652 , A61K9/4816 , A61K9/5026 , A61K9/5047 , A61K47/32
摘要： The present invention is directed to novel pharmaceutically acceptable polymeric compositions suitable for melt extrusion and injection molding of single or multi-component pharmaceutical dosage forms comprising a plurality of drug substance containing sub-units, being capsule compartments and/or solid sub-units comprising a solid matrix of a polymer which contains a drug substance, the sub-units being connected together in the assembled dosage form.
摘要翻译： 本发明涉及适于熔融挤出和注射成型单组分或多组分药物剂型的新型药学上可接受的聚合物组合物，其包含多个含药物物质的子单元，即胶囊隔室和/或固体亚单元，其包含 含有药物的聚合物的固体基质，所述子单元在组装的剂型中连接在一起。
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公开(公告)号：US08147871B2
公开(公告)日：2012-04-03
申请号：US11078077
申请日：2005-03-11
申请人： Adrian Brown , Wayne M. Matthews , Daniel M. Margetson , Stephen Mark McAllister , Ronald K. Raby
发明人： Adrian Brown , Wayne M. Matthews , Daniel M. Margetson , Stephen Mark McAllister , Ronald K. Raby
CPC分类号： A61K9/1617 , A61K9/1623 , A61K9/1647 , A61K9/1652 , A61K9/4816 , A61K9/5026 , A61K9/5047 , A61K47/32
摘要： The present invention is directed to novel pharmaceutically acceptable polymeric compositions suitable for melt extrusion and injection molding of single or multi-component pharmaceutical dosage forms comprising a plurality of drug substance containing sub-units, being capsule compartments and/or solid sub-units comprising a solid matrix of a polymer which contains a drug substance, the sub-units being connected together in the assembled dosage form.
摘要翻译： 本发明涉及适于熔融挤出和注射成型单组分或多组分药物剂型的新型药学上可接受的聚合物组合物，其包含多个含药物物质的子单元，即胶囊隔室和/或固体亚单元，其包含 含有药物的聚合物的固体基质，所述子单元在组装的剂型中连接在一起。
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公开(公告)号：US08361498B2
公开(公告)日：2013-01-29
申请号：US12952677
申请日：2010-11-23
IPC分类号： A61K9/48
CPC分类号： A61K9/4816 , A61K9/4808
摘要： The present invention is directed to pharmaceutically acceptable polymeric compositions suitable for injection molding of single or multi-component pharmaceutical dosage forms comprising a plurality of drug substance containing sub-units, being capsule compartments and/or solid sub-units comprising a solid matrix of a polymer which contains a drug substance, the sub-units being connected together in the assembled dosage form by a weld between parts of the assembled dosage form.
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公开(公告)号：US08673350B2
公开(公告)日：2014-03-18
申请号：US10565462
申请日：2004-07-21
CPC分类号： A61K9/4816 , A61K9/4808 , A61K9/4866
摘要： The present invention is directed to novel pharmaceutically acceptable polymeric compositions suitable for injection molding of single or multi-component pharmaceutical dosage forms comprising a plurality of drug substance containing sub-units, being capsule compartments and/or solid sub-units comprising a solid matrix of a polymer which contains a drug substance, the sub-units being connected together in the assembled dosage form by a weld between parts of the assembled dosage form.
摘要翻译： 本发明涉及适用于注射模塑单组分或多组分药物剂型的新型药学上可接受的聚合物组合物，其包含多个含药物物质的子单元，其为胶囊隔室和/或固体亚单位，其包含固体基质 含有药物的聚合物，所述子单元通过组装的剂型的各部分之间的焊接在组装的剂型中连接在一起。
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公开(公告)号：US07883721B2
公开(公告)日：2011-02-08
申请号：US10470438
申请日：2002-01-30
申请人： Stephen Mark McAllister , Ronald K. Raby, Jr. , Adrian Brown , Allan J. Clarke , Wayne Matthews , Daniel N. Margetson
发明人： Stephen Mark McAllister , Ronald K. Raby, Jr. , Adrian Brown , Allan J. Clarke , Wayne Matthews , Daniel N. Margetson
IPC分类号： A61K9/48
CPC分类号： A61K9/4808 , A61K9/4816
摘要： The present invention is directed to pharmaceutically acceptable polymeric compositions suitable for injection molding of single or multi-component pharmaceutical dosage forms comprising a plurality of drug substance containing sub-units, being capsule compartments and/or solid sub-units comprising a solid matrix of a polymer which contains a drug substance, the sub-units being connected together in the assembled dosage form by a weld between parts of the assembled dosage form.
摘要翻译： 本发明涉及适于注射模塑单组分或多组分药物剂型的药学上可接受的聚合物组合物，其包含多个含药物物质的子单元，包括胶囊隔室和/或包含固体基质的固体亚单元 含有药物的聚合物，所述子单元通过组装的剂型的部分之间的焊接在组装的剂型中连接在一起。
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公开(公告)号：US08367101B2
公开(公告)日：2013-02-05
申请号：US10060849
申请日：2002-01-30
申请人： Stephen Mark McAllister , Ronald K. Raby, Jr. , Adrian Brown , Allan J. Clarke , Daniel N. Margetson , Wayne Matthews
发明人： Stephen Mark McAllister , Ronald K. Raby, Jr. , Adrian Brown , Allan J. Clarke , Daniel N. Margetson , Wayne Matthews
CPC分类号： A61K9/4816 , A61K9/4808 , Y02A50/465
摘要： The present invention is directed to pharmaceutically acceptable polymeric compositions suitable for injection molding of single or multi-component pharmaceutical dosage forms comprising a plurality of drug substance containing sub-units, being capsule compartments and/or solid sub-units comprising a solid matrix of a polymer which contains a drug substance, the sub-units being connected together in the assembled dosage form by a weld between parts of the assembled dosage form.
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公开(公告)号：US20110300212A1
公开(公告)日：2011-12-08
申请号：US13189987
申请日：2011-07-25
申请人： Stephen Mark McAllister , Ronald K. Raby, JR. , Adrian Brown , Allan J. Clarke , Daniel N. Margetson , Wayne Matthews
发明人： Stephen Mark McAllister , Ronald K. Raby, JR. , Adrian Brown , Allan J. Clarke , Daniel N. Margetson , Wayne Matthews
IPC分类号： A61K9/52 , A61K47/34 , A61K47/04 , B32B37/12 , A61K9/00 , A61P43/00 , B29C45/00 , B32B37/00 , A61K47/32 , A61K9/48
CPC分类号： A61K9/4816 , A61K9/4808 , Y02A50/465
摘要： The present invention is directed to pharmaceutically acceptable polymeric compositions suitable for injection molding of single or multi-component pharmaceutical dosage forms comprising a plurality of drug substance containing sub-units, being capsule compartments and/or solid sub-units comprising a solid matrix of a polymer which contains a drug substance, the sub-units being connected together in the assembled dosage form by a weld between parts of the assembled dosage form.
摘要翻译： 本发明涉及适于注射模塑单组分或多组分药物剂型的药学上可接受的聚合物组合物，其包含多个含药物物质的子单元，包括胶囊隔室和/或包含固体基质的固体亚单元 含有药物的聚合物，所述子单元通过组装的剂型的部分之间的焊接在组装的剂型中连接在一起。
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公开(公告)号：US20110123608A1
公开(公告)日：2011-05-26
申请号：US12952677
申请日：2010-11-23
CPC分类号： A61K9/4816 , A61K9/4808
摘要： The present invention is directed to pharmaceutically acceptable polymeric compositions suitable for injection molding of single or multi-component pharmaceutical dosage forms comprising a plurality of drug substance containing sub-units, being capsule compartments and/or solid sub-units comprising a solid matrix of a polymer which contains a drug substance, the sub-units being connected together in the assembled dosage form by a weld between parts of the assembled dosage form.
摘要翻译： 本发明涉及适于注射模塑单组分或多组分药物剂型的药学上可接受的聚合物组合物，其包含多个含药物物质的子单元，包括胶囊隔室和/或包含固体基质的固体亚单元 含有药物的聚合物，所述子单元通过组装的剂型的部分之间的焊接在组装的剂型中连接在一起。
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公开(公告)号：US07842308B2
公开(公告)日：2010-11-30
申请号：US10470439
申请日：2002-01-30
IPC分类号： A61K9/48
CPC分类号： A61K9/4816 , A61K9/4808
摘要： The present invention is directed to pharmaceutically acceptable polymeric compositions suitable for injection molding of single or multi-component pharmaceutical dosage forms comprising a plurality of drug substance containing sub-units, being capsule compartments and/or solid sub-units comprising a solid matrix of a polymer which contains a drug substance, the sub-units being connected together in the assembled dosage form by a weld between parts of the assembled dosage form.
摘要翻译： 本发明涉及适于注射模塑单组分或多组分药物剂型的药学上可接受的聚合物组合物，其包含多个含药物物质的子单元，包括胶囊隔室和/或包含固体基质的固体亚单元 含有药物的聚合物，所述子单元通过组装的剂型的部分之间的焊接在组装的剂型中连接在一起。
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公开(公告)号：US20100074947A1
公开(公告)日：2010-03-25
申请号：US12483477
申请日：2009-06-12
申请人： Adrian Brown , Wayne M. Matthews , Daniel N. Margetson , Stephen Mark McAllister , Danielle Genevieve Rebecca Russell
发明人： Adrian Brown , Wayne M. Matthews , Daniel N. Margetson , Stephen Mark McAllister , Danielle Genevieve Rebecca Russell
IPC分类号： A61K9/48
CPC分类号： A61K9/4816
摘要： The present invention is directed to novel pharmaceutically acceptable polymeric compositions suitable for melt extrusion and injection moulding of single or multi-component pharmaceutical dosage forms comprising a plurality of drug substance containing sub-units, being capsule compartments and/or solid sub-units comprising a solid matrix of a polymer which contains a drug substance, the sub-units being connected together in the assembled dosage form.
摘要翻译： 本发明涉及适于熔融挤出和注射成型单组分或多组分药物剂型的新型药学上可接受的聚合物组合物，其包含多个含药物物质的子单元，即胶囊隔室和/或固体亚单元，其包含 含有药物的聚合物的固体基质，所述子单元在组装的剂型中连接在一起。
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