公开(公告)号：US20030105427A1

公开(公告)日：2003-06-05

申请号：US10010212

申请日：2001-12-04

Applicant: Advanced Cardiovascular Systems, Inc.

Inventor： Jeong S. Lee ,  Kenneth L. Wantink

IPC: A61M029/00

CPC classification number: A61M25/1036 ,  A61M2025/0034 ,  A61M2025/0037

Abstract: A catheter having a polymeric reinforcing member at a junction between shaft sections such as a rapid exchange catheter junction. The polymeric reinforcing member is around or within the tubular member defining the inflation lumen or the tubular member defining the guidewire lumen at the rapid exchange junction to prevent or inhibit damage to the tubular members defining the inflation lumen and/or guidewire lumen during assembly or use of a balloon catheter. In one embodiment, the polymeric reinforcing member is formed of a first polymeric material having a glass transition temperature greater than a glass transition temperature of a second polymeric material forming the distal portion of the proximal tubular member or the proximal portion of the inner tubular member. The first polymeric material forming the polymeric reinforcing member is preferably a high temperature, high modulus material, such as polyimide, and most preferably a thermoset polyimide.

Abstract translation: 导管，其具有在诸如快速交换导管接头的轴部分之间的接合处的聚合物加强构件。 聚合物加强构件在管状构件的周围或内部，限定膨胀腔或管状构件，其在快速交换结处限定导丝管腔，以防止或抑制在组装或使用期间限定充气腔和/或导丝腔的管状构件的损伤 的气球导管。 在一个实施例中，聚合物加强构件由玻璃化转变温度大于形成近端管状部件的远端部分或内部管状部件的近端部分的第二聚合物材料的玻璃化转变温度的第一聚合物材料形成。 形成聚合物增强部件的第一聚合物材料优选是高温高模量材料，例如聚酰亚胺，最优选热固性聚酰亚胺。

公开(公告)号：US20020038103A1

公开(公告)日：2002-03-28

申请号：US10005025

申请日：2001-12-04

Applicant: Advanced Cardiovascular Systems, Inc.

Inventor： Edward A. Estrada ,  Mina W. B. Chow ,  Kenneth L. Wantink ,  Barbara E. Stamberg ,  Chi Le Long

IPC: A61M029/00 ,  A61M031/00 ,  A61M037/00

CPC classification number: A61M25/104 ,  A61M25/007 ,  A61M25/0075 ,  A61M25/09 ,  A61M2025/0063 ,  A61M2025/0183 ,  A61M2025/1079 ,  A61M2025/1093

Abstract: A balloon catheter system generally having an elongated catheter shaft with enhanced flexibility to facilitate more distal advancement within a patient's body lumen. The catheter shaft has a relatively stiff proximal shaft section, a relatively flexible distal shaft section and an intermediate shaft section which provides a smooth, flexible transition between the proximal and distal shaft sections. The intermediate shaft section has an improved construction with a tubular reinforcing member secured by its proximal end to the distal extremity of the proximal shaft section and a distal end secured within the proximal end of the distal shaft section. The tubular reinforcing member preferably has an inner tubular support member which has a proximal end secured to the distal end of the proximal shaft section. Preferably, the proximal shaft section has an outer jacket which extends over the tubular reinforcing member of the intermediate shaft section. Dual lumen and concentric distal shaft sections are describes. Additionally, over-the-wire constructions are described in which the inner and outer tubular members forming part of the distal shaft section extend the length of the catheter.

Abstract translation: 一种气囊导管系统，其通常具有细长的导管轴，该导管轴具有增强的柔性，以便于在患者的体腔内更远的前进。 导管轴具有相对刚性的近端轴部分，相对柔性的远侧轴部分和中间轴部分，其在近端和远端轴部分之间提供平滑的柔性过渡。 中间轴部分具有改进的构造，其中管状加强构件通过其近端固定到近侧轴部分的远端，并且远端固定在远侧轴部分的近端内。 管状加强构件优选地具有内管状支撑构件，其具有固定到近端轴部分的远端的近端。 优选地，近侧轴部分具有在中间轴部分的管状加强件上延伸的外护套。 描述双腔和同心远端轴段。 另外，描述了在线结构，其中形成远侧轴部分的一部分的内部和外部管状构件延伸导管的长度。

公开(公告)号：US20030083616A1

公开(公告)日：2003-05-01

申请号：US10002933

申请日：2001-11-01

Applicant: Advanced Cardiovascular Systems, Inc.

Inventor： Jeong S. Lee ,  Kenneth L. Wantink

IPC: A61M029/00

CPC classification number: A61L2/087 ,  A61L2202/24 ,  A61M25/10

Abstract: A method of sterilizing a medical device component, such as a catheter balloon, in which an electron beam (i.e., e-beam) is applied to the component in an evacuated or inert gas-filled container. The method of the invention allows for electron beam sterilization without significant degradation of the component polymeric material. In one embodiment, the device component is configured to be pressurized or expanded during use. The method of the invention provides a component with a rupture pressure that is not significantly decreased due to electron beam sterilization. Another aspect of the invention is a medical device component, e-beam sterilized according to a method of the invention. A variety of medical device components can be sterilized by the method of the invention, and particularly intracorporeal devices for therapeutic or diagnostic purposes, such as balloon catheters, catheter shafts and balloons, stent covers, and vascular grafts.

Abstract translation: 对在真空或惰性气体填充的容器中的组件施加电子束（即电子束）的医疗装置部件（例如导管球囊）进行灭菌的方法。 本发明的方法允许电子束灭菌而不会显着降低组分聚合物材料。 在一个实施例中，装置部件构造成在使用期间被加压或膨胀。 本发明的方法提供了由于电子束灭菌而没有显着降低的断裂压力的部件。 本发明的另一方面是根据本发明的方法消毒的电子束的医疗装置部件。 可以通过本发明的方法，特别是用于治疗或诊断目的的体内器件，例如球囊导管，导管轴和球囊，支架盖和血管移植物来消毒各种医疗装置部件。

公开(公告)号：US20030032920A1

公开(公告)日：2003-02-13

申请号：US09924380

申请日：2001-08-07

Applicant: Advanced Cardiovascular Systems, Inc.

Inventor： Kenneth L. Wantink

IPC: A61M029/00

CPC classification number: A61M25/001 ,  A61M25/0069 ,  A61M25/10 ,  A61M2025/1093

Abstract: A balloon catheter having an improved maneuverability. The catheter includes an elongated catheter shaft with proximal and distal ends, proximal and distal shaft sections, a balloon on the distal catheter shaft section having proximal and distal shaft sections, a guidewire receiving lumen extending along at least a portion of the catheter shaft to the catheter shaft distal end, and a tip member on a distal end of the catheter. A proximal end of the tip member is spaced distally apart from the distal end of the catheter shaft and is in fluid communication therewith. The distal balloon shaft is sealingly secured to the catheter shaft and the tip member.

Abstract translation: 具有改善的机动性的气囊导管。 导管包括细长的导管轴，其具有近端和远端，近端和远端轴段，远端导管轴部分上具有近端和远端轴段的气囊，沿着导管轴的至少一部分延伸至 导管轴远端，以及在导管的远端上的尖端构件。 尖端构件的近端与导管轴的远端远离地间隔开并与其形成流体连通。 远端球囊轴密封地固定到导管轴和尖端部件上。